The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This
protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in chromatin remodeling; regulation of cell cycle; and regulation of nucleobase-containing compound metabolic process. Located in nucleoplasm. Is expressed in genitourinary system; sensory organ; tooth; and trun