| 1321517 | GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq, Jul 2008] | 12 | 51351252 | 51391673 | Human | 122 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1321518 | Galnt6 | polypeptide N-acetylgalactosaminyltransferase 6 | Enables polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation via threonine. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in Golgi apparatus. Is expressed in exocrine system; paravertebral ganglion; an d skeleton. Orthologous to human GALNT6 (polypeptide N-acetylgalactosaminyltransferase 6). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 100587796 | 100627257 | Mouse | 121 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 2319726 | Galnt6 | polypeptide N-acetylgalactosaminyltransferase 6 | ENCODES a protein that exhibits polypeptide N-acetylgalactosaminyltransferase activity (ortholog); INVOLVED IN protein O-linked glycosylation via N-acetyl-galactosamine (ortholog); PARTICIPATES IN O-linked glycan biosynthetic pathway; FOUND IN Golgi apparatus (ortholog); perinuclear region of cytopl asm (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 7 | 133668612 | 133715909 | Rat | 120 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 8819963 | Galnt6 | polypeptide N-acetylgalactosaminyltransferase 6 | ENCODES a protein that exhibits polypeptide N-acetylgalactosaminyltransferase activity (ortholog); INVOLVED IN protein O-linked glycosylation via N-acetyl-galactosamine (ortholog); FOUND IN Golgi apparatus (ortholog); perinuclear region of cytoplasm (ortholog) | NW_004955547 | 1828767 | 1859327 | Chinchilla | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11994799 | GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | ENCODES a protein that exhibits carbohydrate binding (inferred); glycosyltransferase activity (inferred); metal ion binding (inferred); INVOLVED IN protein O-linked glycosylation (inferred); protein O-linked glycosylation via N-acetyl-galactosamine (inferred); FOUND IN Golgi apparatus (inferred); Go lgi membrane (inferred); perinuclear region of cytoplasm (inferred) | 12 | 37361418 | 37401927 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12243256 | GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | ENCODES a protein that exhibits carbohydrate binding (inferred); glycosyltransferase activity (inferred); metal ion binding (inferred); INVOLVED IN protein O-linked glycosylation via N-acetyl-galactosamine (inferred); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred); perinuclear region of cytoplasm (inferred) | 27 | 3507314 | 3539263 | Dog | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12537196 | Galnt6 | polypeptide N-acetylgalactosaminyltransferase 6 | ENCODES a protein that exhibits carbohydrate binding (inferred); glycosyltransferase activity (inferred); metal ion binding (inferred); INVOLVED IN protein O-linked glycosylation (inferred); protein O-linked glycosylation via N-acetyl-galactosamine (inferred); FOUND IN Golgi apparatus (inferred); Go lgi membrane (inferred); perinuclear region of cytoplasm (inferred) | NW_004936512 | 8932129 | 8960494 | Squirrel | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18934513 | Galnt6 | polypeptide N-acetylgalactosaminyltransferase 6 | ENCODES a protein that exhibits carbohydrate binding (inferred); glycosyltransferase activity (inferred); metal ion binding (inferred); INVOLVED IN protein O-linked glycosylation (inferred); protein O-linked glycosylation via N-acetyl-galactosamine (inferred); FOUND IN Golgi apparatus (inferred); Go lgi membrane (inferred); perinuclear region of cytoplasm (inferred) | | | | Naked Mole-Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18409222 | GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | ENCODES a protein that exhibits carbohydrate binding (inferred); glycosyltransferase activity (inferred); metal ion binding (inferred); INVOLVED IN protein O-linked glycosylation (inferred); protein O-linked glycosylation via N-acetyl-galactosamine (inferred); FOUND IN Golgi apparatus (inferred); Go lgi membrane (inferred); perinuclear region of cytoplasm (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625965167 | Galnt6 | polypeptide N-acetylgalactosaminyltransferase 6 | ENCODES a protein that exhibits polypeptide N-acetylgalactosaminyltransferase activity (ortholog); INVOLVED IN protein O-linked glycosylation via N-acetyl-galactosamine (ortholog); FOUND IN Golgi apparatus (ortholog); perinuclear region of cytoplasm (ortholog) | | | | Black Rat | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13923958 | GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | ENCODES a protein that exhibits carbohydrate binding (inferred); glycosyltransferase activity (inferred); metal ion binding (inferred); INVOLVED IN protein O-linked glycosylation via N-acetyl-galactosamine (inferred); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred); perinuclear region of cytoplasm (inferred); INTERACTS WITH deoxynivalenol; zearalenone | | | | Pig | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155255492 | galnt6.1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155246110 | galnt6.2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 287860527 | galnt6.3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155255493 | galnt6.1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155256777 | galnt6.1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155241325 | galnt6.2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155256707 | galnt6.2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 287814240 | galnt6.3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1613172 | Galnt6os | polypeptide N-acetylgalactosaminyltransferase 6, opposite strand | INTERACTS WITH titanium dioxide | 15 | 100593613 | 100599387 | Mouse | 4 | symbol , PhenoGen | gene, ncrna, MODEL [RefSeq] |