| 1345094 | GALNT4 | polypeptide N-acetylgalactosaminyltransferase 4 | This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. Fusion transcripts, which combine part of this gene with the 5' exons of the neighboring POC1B (POC1 centriolar protein homolog B) gene, also exist. [provided by RefSeq, Dec 2010] | 12 | 89519412 | 89524796 | Human | 73 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1557722 | Galnt4 | polypeptide N-acetylgalactosaminyltransferase 4 | Predicted to enable manganese ion binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation via serine and protein O-linked glycosylation via threonine. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in Golgi apparatus. Is expressed in several structures, including exocrine system; extraembryonic component; gut; and skeleton. Orthologous to several human genes including GALNT4 (polypeptide N-acetylgalactosaminyltransferase 4). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 98943997 | 98949109 | Mouse | 78 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564589 | Galnt4 | polypeptide N-acetylgalactosaminyltransferase 4 | ENCODES a protein that exhibits manganese ion binding (ortholog); polypeptide N-acetylgalactosaminyltransferase activity (ortholog); INVOLVED IN protein O-linked glycosylation via N-acetyl-galactosamine (ortholog); PARTICIPATES IN O-linked glycan biosynthetic pathway; FOUND IN Golgi apparatus (ortho log); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil | 7 | 35811904 | 35814445 | Rat | 59 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8916479 | Galnt4 | polypeptide N-acetylgalactosaminyltransferase 4 | ENCODES a protein that exhibits manganese ion binding (ortholog); polypeptide N-acetylgalactosaminyltransferase activity (ortholog); INVOLVED IN protein O-linked glycosylation via N-acetyl-galactosamine (ortholog); FOUND IN Golgi apparatus (ortholog); perinuclear region of cytoplasm (ortholog) | NW_004956666 | 67 | 3521 | Chinchilla | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13881557 | GALNT4 | polypeptide N-acetylgalactosaminyltransferase 4 | ENCODES a protein that exhibits carbohydrate binding (inferred); glycosyltransferase activity (inferred); manganese ion binding (inferred); INVOLVED IN protein O-linked glycosylation via N-acetyl-galactosamine (inferred); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred); perinuclear re gion of cytoplasm (inferred) | | | | Pig | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922906 | Galnt4 | polypeptide N-acetylgalactosaminyltransferase 4 | ENCODES a protein that exhibits manganese ion binding (ortholog); INVOLVED IN protein O-linked glycosylation (inferred); protein O-linked glycosylation via N-acetyl-galactosamine (inferred); FOUND IN perinuclear region of cytoplasm (ortholog) | | | | Naked Mole-Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155233336 | galnt4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155233337 | galnt4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 5507979 | POC1B-GALNT4 | POC1B-GALNT4 readthrough | This locus represents naturally occurring transcripts that splice the 5' exons of the POC1B (POC1 centriolar protein homolog B) gene on chromosome 12 to the GALNT4 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4) gene, which i s located within a POC1B intron. Alternative splicing results in two transcript variants, one of which encodes a fusion isoform that shares sequence identity with the products of each individual gene. [provided by RefSeq, Dec 2010] | 12 | 89519412 | 89526262 | Human | 29 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11967301 | POC1B | POC1 centriolar protein B | INVOLVED IN acrosome assembly (ortholog); cell morphogenesis (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); cone-rod dystrophy 20 (ortholog); fundus dystrophy (ortholog); FOUND IN centriole (inferred); centrosome (inferred); ciliary basal body ( inferred) | 12 | 86946987 | 87053789 | Bonobo | 35 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12332208 | POC1B | POC1 centriolar protein B | ENCODES a protein that exhibits carbohydrate binding (inferred); glycosyltransferase activity (inferred); metal ion binding (inferred); INVOLVED IN acrosome assembly (ortholog); cell morphogenesis (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); c one-rod dystrophy 20 (ortholog); fundus dystrophy (ortholog); FOUND IN centriole (inferred); centrosome (inferred); ciliary basal body (inferred); INTERACTS WITH bisphenol A | 15 | 30388351 | 30481294 | Dog | 43 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
