| 621715 | Foxd3 | forkhead box D3 | ENCODES a protein that exhibits DNA binding; double-stranded DNA binding; DNA-binding transcription factor activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); embryonic placenta development (ortholog); in utero embryonic development (ortholog); ASSOCIATED WIT H glaucoma (ortholog); intellectual disability (ortholog); vitiligo (ortholog); FOUND IN chromatin (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; 1,2-dichloroethane (ortholog) | 5 | 119450532 | 119452898 | Rat | 101 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 736441 | Foxd3 | forkhead box D3 | Enables DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Involved in in utero embryonic development and negative regulation of transcription by RNA polymerase II. Acts upstream of or within cellular response to leukemia inhibitory factor; embryonic placenta development; and trophectodermal cell differentiation. Predicted to be located in chromatin. Predicted to be part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system; and sensory organ. Human ortholog(s) of this gene implicated in vitiligo. Orthologous to human FOXD3 (forkhead box D3). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 99544536 | 99546908 | Mouse | 136 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1347778 | FOXD3 | forkhead box D3 | This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. Mutations in this gene cause autoimmune susceptibility 1. [provided by RefSeq, Nov 2008] | 1 | 63322567 | 63325128 | Human | 94 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 12204919 | FOXD3 | forkhead box D3 | ENCODES a protein that exhibits DNA binding (ortholog); double-stranded DNA binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); embryonic placenta development (ortholog); in utero embryonic development (o rtholog); ASSOCIATED WITH glaucoma (ortholog); intellectual disability (ortholog); vitiligo (ortholog); FOUND IN chromatin (inferred); nucleus (inferred) | 5 | 46818856 | 46821915 | Dog | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12735304 | Foxd3 | forkhead box D3 | ENCODES a protein that exhibits DNA binding (ortholog); double-stranded DNA binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); embryonic placenta development (ortholog); in utero embryonic development (o rtholog); ASSOCIATED WITH glaucoma (ortholog); intellectual disability (ortholog); vitiligo (ortholog); FOUND IN chromatin (inferred); nucleus (inferred) | NW_004936692 | 951394 | 953612 | Squirrel | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 32732548 | FOXD3 | forkhead box D3 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); embryonic placenta development (o rtholog); in utero embryonic development (ortholog); ASSOCIATED WITH glaucoma (ortholog); intellectual disability (ortholog); vitiligo (ortholog); FOUND IN chromatin (ortholog) | 1 | 62577800 | 62580360 | Bonobo | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231068 | foxd3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18766873 | FOXD3 | forkhead box D3 | ENCODES a protein that exhibits DNA binding (ortholog); double-stranded DNA binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); embryonic placenta development (ortholog); in utero embryonic development (o rtholog); ASSOCIATED WITH glaucoma (ortholog); intellectual disability (ortholog); vitiligo (ortholog); FOUND IN chromatin (inferred); nucleus (inferred) | | | | Green Monkey | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14225941 | FOXD3 | forkhead box D3 | ENCODES a protein that exhibits DNA binding (ortholog); double-stranded DNA binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); embryonic placenta development (ortholog); in utero embryonic development (o rtholog); ASSOCIATED WITH glaucoma (ortholog); intellectual disability (ortholog); vitiligo (ortholog); FOUND IN chromatin (inferred); nucleus (inferred) | | | | Pig | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625868062 | Foxd3 | forkhead box D3 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); embryonic placenta development (o rtholog); in utero embryonic development (ortholog); ASSOCIATED WITH glaucoma (ortholog); intellectual disability (ortholog); vitiligo (ortholog); FOUND IN chromatin (ortholog) | | | | Black Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237315 | foxd3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155231316 | foxd3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 8661374 | FOXD3-AS1 | FOXD3 antisense RNA 1 | INTERACTS WITH perfluorooctanoic acid; phytoestrogen; propofol | 1 | 63320884 | 63324441 | Human | 3 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |
| 1607458 | Foxd3os | Forkhead box D3 opposite strand | ASSOCIATED WITH no abnormal phenotype detected | | | | Mouse | 1 | symbol , PhenoGen | gene, protein-coding |
