| 1565003 | Retreg1 | reticulophagy regulator 1 | ENCODES a protein that exhibits endoplasmic reticulum-autophagosome adaptor activity (ortholog); INVOLVED IN autophagy (ortholog); collagen catabolic process (ortholog); endoplasmic reticulum organization (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); genetic disease (ortholog); hereditary sensory and autonomic neuropathy type 2 (ortholog); FOUND IN cis-Golgi network (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 2 | 78045435 | 78205316 | Rat | 189 | old_gene_name , ensembl_full_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1601869 | RETREG1 | reticulophagy regulator 1 | The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a r ole in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] | 5 | 16473053 | 16616997 | Human | 244 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1614369 | Retreg1 | reticulophagy regulator 1 | Enables endoplasmic reticulum-autophagosome adaptor activity. Involved in negative regulation of neuron apoptotic process. Acts upstream of or within several processes, including collagen catabolic process; macroautophagy; and white fat cell differentiation. Located in cis-Golgi network and endoplas mic reticulum. Is expressed in several structures, including alimentary system; central nervous system; ganglia; metanephros; and reproductive system. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 2B. Orthologous to human RETREG1 (reticulophagy regulator 1). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 25840795 | 25973782 | Mouse | 186 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8944585 | Retreg1 | reticulophagy regulator 1 | ENCODES a protein that exhibits endoplasmic reticulum-autophagosome adaptor activity (ortholog); INVOLVED IN autophagy (ortholog); collagen catabolic process (ortholog); endoplasmic reticulum organization (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); genetic disease (ortholog); hereditary sensory and autonomic neuropathy type 2 (ortholog); FOUND IN cis-Golgi network (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog) | NW_004955426 | 5574207 | 5688236 | Chinchilla | 31 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 11925621 | RETREG1 | reticulophagy regulator 1 | ENCODES a protein that exhibits endoplasmic reticulum-autophagosome adaptor activity (inferred); INVOLVED IN autophagy (ortholog); collagen catabolic process (ortholog); endoplasmic reticulum organization (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); genetic disease (ortholog); hereditary sensory and autonomic neuropathy type 2 (ortholog); FOUND IN cis-Golgi network (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred) | 5 | 16774596 | 16920948 | Bonobo | 34 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12057336 | RETREG1 | reticulophagy regulator 1 | ENCODES a protein that exhibits endoplasmic reticulum-autophagosome adaptor activity (ortholog); INVOLVED IN autophagy (ortholog); collagen catabolic process (ortholog); endoplasmic reticulum organization (ortholog); ASSOCIATED WITH Vesicoureteral Reflux 5; Charcot-Marie-Tooth disease (ortholog); ge netic disease (ortholog); FOUND IN cis-Golgi network (ortholog) | 4 | 86817391 | 86921119 | Dog | 50 | old_gene_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12514543 | Retreg1 | reticulophagy regulator 1 | ENCODES a protein that exhibits endoplasmic reticulum-autophagosome adaptor activity (inferred); INVOLVED IN autophagy (ortholog); collagen catabolic process (ortholog); endoplasmic reticulum organization (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); genetic disease (ortholog); hereditary sensory and autonomic neuropathy type 2 (ortholog); FOUND IN cis-Golgi network (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred) | NW_004936480 | 19114753 | 19253346 | Squirrel | 36 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18625104 | RETREG1 | reticulophagy regulator 1 | ENCODES a protein that exhibits endoplasmic reticulum-autophagosome adaptor activity (inferred); INVOLVED IN autophagy (ortholog); collagen catabolic process (ortholog); endoplasmic reticulum organization (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); genetic disease (ortholog); hereditary sensory and autonomic neuropathy type 2 (ortholog); FOUND IN cis-Golgi network (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred) | | | | Green Monkey | 36 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921595 | Retreg1 | reticulophagy regulator 1 | ENCODES a protein that exhibits endoplasmic reticulum-autophagosome adaptor activity (ortholog); INVOLVED IN autophagy (ortholog); collagen catabolic process (ortholog); endoplasmic reticulum organization (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); genetic disease (ortholog); hereditary sensory and autonomic neuropathy type 2 (ortholog); FOUND IN cis-Golgi network (ortholog) | | | | Naked Mole-Rat | 31 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14154180 | RETREG1 | reticulophagy regulator 1 | ENCODES a protein that exhibits endoplasmic reticulum-autophagosome adaptor activity (inferred); INVOLVED IN autophagy (ortholog); collagen catabolic process (ortholog); endoplasmic reticulum organization (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); genetic disease (ortholog); hereditary sensory and autonomic neuropathy type 2 (ortholog); FOUND IN cis-Golgi network (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred) | | | | Pig | 36 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 8715832 | LOC102028511 | protein FAM134B pseudogene | | NW_004955464 | 7935764 | 7936955 | Chinchilla | | name | gene, pseudo, MODEL [RefSeq] |
| 18918699 | LOC101703849 | reticulophagy receptor FAM134B pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18899964 | LOC101714177 | reticulophagy receptor FAM134B pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18922212 | LOC101724930 | reticulophagy receptor FAM134B pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 16557979 | RETREG1-AS1 | RETREG1 antisense RNA 1 | | 5 | 16615926 | 16629969 | Human | | old_gene_name | gene, ncrna, VALIDATED [RefSeq] |