| 1309868 | Ei24 | EI24, autophagy associated transmembrane protein | ENCODES a protein that exhibits importin-alpha family protein binding (ortholog); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Prostatic Neopl asms (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 1,3-dinitrobenzene | 8 | 44683138 | 44699502 | Rat | 131 | symbol , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1320441 | EI24 | EI24 autophagy associated transmembrane protein | This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochon drial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014] | 11 | 125569477 | 125584684 | Human | 131 | symbol , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320442 | Ei24 | etoposide induced 2.4 mRNA | Predicted to enable importin-alpha family protein binding activity. Acts upstream of or within several processes, including cellular response to UV-C; intrinsic apoptotic signaling pathway in response to DNA damage; and negative regulation of protein import into nucleus. Predicted to be located in G olgi apparatus and cytosol. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human EI24 (EI24 autophagy associated transmembrane protein). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 36690449 | 36708630 | Mouse | 176 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8837074 | Ei24 | EI24 autophagy associated transmembrane protein | ENCODES a protein that exhibits importin-alpha family protein binding (ortholog); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (orth olog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog) | NW_004955412 | 26574814 | 26586154 | Chinchilla | 14 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11675289 | EI24 | EI24 autophagy associated transmembrane protein | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (infe rred); endoplasmic reticulum (inferred); membrane (inferred) | 11 | 120389136 | 120404347 | Bonobo | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12430242 | EI24 | EI24 autophagy associated transmembrane protein | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (infe rred); membrane (inferred) | 5 | 8949886 | 8963967 | Dog | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12700975 | Ei24 | EI24 autophagy associated transmembrane protein | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (infe rred); endoplasmic reticulum (inferred); membrane (inferred) | NW_004936743 | 1957948 | 1970885 | Squirrel | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 625842856 | Ei24 | EI24 autophagy associated transmembrane protein | ENCODES a protein that exhibits importin-alpha family protein binding (ortholog); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (orth olog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog) | | | | Black Rat | 14 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18500667 | EI24 | EI24 autophagy associated transmembrane protein | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (infe rred); endoplasmic reticulum (inferred); membrane (inferred) | | | | Green Monkey | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 13976235 | EI24 | EI24 autophagy associated transmembrane protein | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (infe rred); membrane (inferred) | | | | Pig | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18936758 | Ei24 | EI24 autophagy associated transmembrane protein | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (infe rred); endoplasmic reticulum (inferred); membrane (inferred) | | | | Naked Mole-Rat | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 284579082 | ei24 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 287774226 | ei24.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 286218507 | ei24.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 2323573 | EI24-ps1 | EI24, autophagy associated transmembrane protein, pseudogene 1 | | 1 | 72927771 | 72929829 | Rat | | symbol , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |
| 18914393 | Adam17 | ADAM metallopeptidase domain 17 | ENCODES a protein that exhibits cytokine binding (ortholog); endopeptidase activity (ortholog); integrin binding (ortholog); INVOLVED IN amyloid precursor protein catabolic process (ortholog); B cell differentiation (ortholog); cell adhesion (ortholog); PARTICIPATES IN epidermal growth factor/neureg ulin signaling pathway; interleukin-6 signaling pathway; Notch signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); atopic dermatitis (ortholog); Blister (ortholog); FOUND IN actin cytoskeleton (ortholog); apical part of cell (ortholog); apical plasma membrane (ortholog) | | | | Naked Mole-Rat | 149 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 7175183 | EI24P1 | EI24 pseudogene 1 | | 3 | 176067836 | 176068900 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7175199 | EI24P2 | EI24 pseudogene 2 | | 1 | 158454116 | 158455468 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7175253 | EI24P3 | EI24 pseudogene 3 | | 3 | 44524452 | 44525869 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7175201 | EI24P4 | EI24 pseudogene 4 | | 7 | 145004927 | 145006344 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7175197 | EI24P5 | EI24 pseudogene 5 | | 8 | 53194346 | 53195375 | Human | | symbol , GTEx , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 155783007 | EI24P6 | EI24 pseudogene 6 | | 3 | 176069107 | 176069252 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16565959 | EI24P6 | EI24 pseudogene 6 | | | | | Human | | symbol , COSMIC , name , Human Proteome Map | gene, processed_pseudogene |