| 1307808 | Efna4 | ephrin A4 | ENCODES a protein that exhibits ephrin receptor binding (ortholog); INVOLVED IN ephrin receptor signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); side of membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalan ol | 2 | 177046463 | 177050713 | Rat | 82 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1317216 | EFNA4 | ephrin A4 | This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structur es and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin that has been implicated in proliferation and metastasis of several types of cancers. [provided by RefSeq, May 2022] | 1 | 155063740 | 155069553 | Human | 87 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1317217 | Efna4 | ephrin A4 | Predicted to enable ephrin receptor binding activity. Predicted to be involved in axon guidance and ephrin receptor signaling pathway. Predicted to be located in side of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nerv ous system; genitourinary system; limb; and thymus. Orthologous to human EFNA4 (ephrin A4). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 89240700 | 89245335 | Mouse | 89 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8747246 | Efna4 | ephrin A4 | ENCODES a protein that exhibits ephrin receptor binding (ortholog) | NW_004955545 | 1557107 | 1561234 | Chinchilla | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11746506 | EFNA4 | ephrin A4 | ENCODES a protein that exhibits ephrin receptor binding (inferred); INVOLVED IN axon guidance (inferred); ephrin receptor signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); side of membrane (inferred) | 1 | 130410991 | 130417593 | Bonobo | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12179954 | EFNA4 | ephrin A4 | ENCODES a protein that exhibits ephrin receptor binding (inferred); immunoglobulin receptor binding (inferred); integrin binding (inferred); INVOLVED IN cellular response to phorbol 13-acetate 12-myristate (inferred); ephrin receptor signaling pathway (inferred); immune response to tumor cell (infer red); FOUND IN cell surface (inferred); endomembrane system (inferred); extracellular exosome (inferred) | 7 | 42427539 | 42431788 | Dog | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12617010 | Efna4 | ephrin A4 | ENCODES a protein that exhibits ephrin receptor binding (inferred); INVOLVED IN axon guidance (inferred); ephrin receptor signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); side of membrane (inferred) | NW_004936580 | 4598748 | 4604293 | Squirrel | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18422081 | EFNA4 | ephrin A4 | ENCODES a protein that exhibits ephrin receptor binding (inferred); INVOLVED IN axon guidance (inferred); ephrin receptor signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); side of membrane (inferred) | | | | Green Monkey | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625910318 | Efna4 | ephrin A4 | ENCODES a protein that exhibits ephrin receptor binding (ortholog) | | | | Black Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285891574 | efna4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18935398 | Efna4 | ephrin A4 | ENCODES a protein that exhibits ephrin receptor binding (inferred); INVOLVED IN axon guidance (inferred); ephrin receptor signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); side of membrane (inferred) | | | | Naked Mole-Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13999440 | EFNA4 | ephrin A4 | ENCODES a protein that exhibits ephrin receptor binding (inferred); INVOLVED IN ephrin receptor signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); side of membrane (inferred) | | | | Pig | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285891935 | efna4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864253 | efna4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626469015 | efna4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857199 | efna4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857140 | efna4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859568 | efna4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 152995338 | EFNA4-EFNA3 | EFNA4-EFNA3 readthrough | This locus represents naturally occurring readthrough transcription between the neighboring EFNA4 (ephrin A4) and EFNA3 (ephrin A3) genes on chromosome 1. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Jun 2022] | 1 | 155063740 | 155087538 | Human | 7 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 152995319 | ADAM15-EFNA4 | ADAM15-EFNA4 readthrough | This locus represents naturally occurring readthrough transcription between the neighboring ADAM15 (ADAM metallopeptidase domain 15) and EFNA4 (ephrin A4) genes on chromosome 1. The readthrough transcript is a candidate for nonsense-mediated mRNA decay (NMD), an d is unlikely to produce a protein product. [provided by RefSeq, Jun 2022] | 1 | 155051316 | 155069553 | Human | | symbol , GTEx , COSMIC , name , description , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16559182 | AL691442.1 | novel ephrin-A4 (EFNA4) and ephrin-A3 (EFNA3) protein | | | | | Human | | name | gene, protein-coding |
