| 1308073 | Edf1 | endothelial differentiation-related factor 1 | ENCODES a protein that exhibits TFIID-class transcription factor complex binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN cell differentiation (inferred); DNA-templated transcription (inferred); positive regulation of DNA-templated transcription (inferred); ASSOCIATED W ITH developmental and epileptic encephalopathy 14 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 3 | 28764906 | 28779499 | Rat | 91 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1317635 | EDF1 | endothelial differentiation related factor 1 | This gene encodes a protein that may regulate endothelial cell differentiation, lipid metabolism, and hormone-induced cardiomyocyte hypertrophy. The encoded protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding pr otein (TBP) and gene-specific activators. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] | 9 | 136862119 | 136866308 | Human | 103 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1317636 | Edf1 | endothelial differentiation-related factor 1 | Predicted to enable TFIID-class transcription factor complex binding activity and transcription coactivator activity. Predicted to be involved in cell differentiation and positive regulation of DNA-templated transcription. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Orthologous to human EDF1 (endothelial differentiation related factor 1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 25447838 | 25452096 | Mouse | 103 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8956908 | Edf1 | endothelial differentiation related factor 1 | ENCODES a protein that exhibits TFIID-class transcription factor complex binding (ortholog); transcription coactivator activity (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleolus (ortholog) | NW_004955513 | 4942268 | 4945645 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11733580 | EDF1 | endothelial differentiation related factor 1 | ENCODES a protein that exhibits DNA binding (inferred); TFIID-class transcription factor complex binding (inferred); transcription coactivator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH devel opmental and epileptic encephalopathy 14 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred) | 9 | 107919200 | 107923415 | Bonobo | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12308592 | EDF1 | endothelial differentiation related factor 1 | ENCODES a protein that exhibits TFIID-class transcription factor complex binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN DNA-templated transcription (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); FOUND IN cytoplasm (ortholog); cyt osol (ortholog); nucleolus (ortholog) | 9 | 48722918 | 48726358 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12676374 | Edf1 | endothelial differentiation related factor 1 | ENCODES a protein that exhibits DNA binding (inferred); TFIID-class transcription factor complex binding (inferred); transcription coactivator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH devel opmental and epileptic encephalopathy 14 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred) | NW_004936669 | 1051137 | 1055168 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626028224 | Edf1 | endothelial differentiation related factor 1 | ENCODES a protein that exhibits TFIID-class transcription factor complex binding (ortholog); transcription coactivator activity (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleolus (ortholog) | | | | Black Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14211375 | EDF1 | endothelial differentiation related factor 1 | ENCODES a protein that exhibits DNA binding (inferred); TFIID-class transcription factor complex binding (inferred); transcription coactivator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH devel opmental and epileptic encephalopathy 14 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred) | | | | Pig | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18904446 | Edf1 | endothelial differentiation related factor 1 | ENCODES a protein that exhibits TFIID-class transcription factor complex binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN DNA-templated transcription (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); FOUND IN cytoplasm (ortholog); cyt osol (ortholog); nucleolus (ortholog) | | | | Naked Mole-Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18597431 | EDF1 | endothelial differentiation related factor 1 | ENCODES a protein that exhibits DNA binding (inferred); TFIID-class transcription factor complex binding (inferred); transcription coactivator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH devel opmental and epileptic encephalopathy 14 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred) | | | | Green Monkey | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250950 | edf1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155250951 | edf1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155259411 | edf1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 40957482 | Edf1-ps1 | endothelial differentiation-related factor 1, pseudogene 1 | | 8 | 34673949 | 34674377 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 2319464 | Edf1-ps2 | endothelial differentiation-related factor 1, pseudogene 2 | | 4 | 149890643 | 149932233 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1594273 | Edf1-ps3 | endothelial differentiation-related factor 1, pseudogene 3 | | 18 | 70304756 | 70305483 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1589009 | Edf1-ps4 | endothelial differentiation-related factor 1, pseudogene 4 | | 16 | 55221334 | 55221767 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |