| 1309047 | Dmrt2 | doublesex and mab-3 related transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN embryonic skeletal system development (or tholog); positive regulation of myotome development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH gonadal dysgenesis (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 232743935 | 232750431 | Rat | 77 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1319169 | DMRT2 | doublesex and mab-3 related transcription factor 2 | The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated w ith gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010] | 9 | 1050357 | 1057552 | Human | 77 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1319170 | Dmrt2 | doublesex and mab-3 related transcription factor 2 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within embryonic skeletal system development; positive regulation of myotome development; and regulation of somitogenesis. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; branchial arch; embryo mesenchyme; genitourinary system; and long bone. Orthologous to human DMRT2 (doublesex and mab-3 related transcription factor 2). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 25649758 | 25656355 | Mouse | 98 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9026452 | Dmrt2 | doublesex and mab-3 related transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN embryonic skeletal system development (or tholog); positive regulation of myotome development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH gonadal dysgenesis (ortholog) | NW_004955434 | 5528625 | 5535783 | Chinchilla | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12020831 | DMRT2 | doublesex and mab-3 related transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); identical protein binding (inferred); INVOLVED IN embryonic skeletal system development (ortholog); p ositive regulation of myotome development (ortholog); regulation of somitogenesis (ortholog); ASSOCIATED WITH gonadal dysgenesis (ortholog); FOUND IN nucleus (inferred) | 9 | 860271 | 867704 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12360875 | DMRT2 | doublesex and mab-3 related transcription factor 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); identical protein binding (inferred); INVOLVED IN embryonic skeletal system development (ortholog); positive regulation of myotome development (ortholog); regu lation of somitogenesis (ortholog); ASSOCIATED WITH gonadal dysgenesis (ortholog); FOUND IN nucleus (inferred) | 1 | 89873380 | 89880944 | Dog | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12631943 | Dmrt2 | doublesex and mab-3 related transcription factor 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN embryonic skeletal system development (ortholog); positive regula tion of myotome development (ortholog); regulation of somitogenesis (ortholog); ASSOCIATED WITH gonadal dysgenesis (ortholog); FOUND IN nucleus (inferred) | NW_004936503 | 3857165 | 3864130 | Squirrel | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626011733 | Dmrt2 | doublesex and mab-3 related transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN embryonic skeletal system development (or tholog); positive regulation of myotome development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH gonadal dysgenesis (ortholog) | | | | Black Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13857053 | DMRT2 | doublesex and mab-3 related transcription factor 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); identical protein binding (inferred); INVOLVED IN embryonic skeletal system development (ortholog); positive regulation of myotome development (ortholog); regu lation of somitogenesis (ortholog); ASSOCIATED WITH gonadal dysgenesis (ortholog); FOUND IN nucleus (inferred) | | | | Pig | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18900351 | Dmrt2 | doublesex and mab-3 related transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN embryonic skeletal system development (or tholog); positive regulation of myotome development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH gonadal dysgenesis (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 40894225 | DMRT2 | doublesex and mab-3 related transcription factor 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN embryonic skeletal system development (ortholog); positive regula tion of myotome development (ortholog); regulation of somitogenesis (ortholog); ASSOCIATED WITH gonadal dysgenesis (ortholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 286713567 | dmrt2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 39131392 | DMRT2 | doublesex and mab-3 related transcription factor 2 | | | | | Chinchilla | | symbol | gene, protein-coding |
| 286301970 | dmrt2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 287687001 | dmrt2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 8547594 | LINC-ADAIN | long intergenic non-coding adipose anti-inflammatory | INTERACTS WITH lipopolysaccharide; S-(1,2-dichlorovinyl)-L-cysteine | 9 | 1048143 | 1048641 | Human | 3 | old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |