| 621744 | Ddx20 | DEAD-box helicase 20 | ENCODES a protein that exhibits protein domain specific binding; DNA-binding transcription factor binding (ortholog); histone deacetylase binding (ortholog); INVOLVED IN negative regulation of cell population proliferation; negative regulation of DNA-templated transcription; negative regulation of t ranscription by RNA polymerase II (ortholog); PARTICIPATES IN RNA transport pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN cytosol (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 2 | 195847105 | 195859989 | Rat | 136 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1320818 | DDX20 | DEAD-box helicase 20 | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splic eosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008] | 1 | 111755901 | 111768000 | Human | 144 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320819 | Ddx20 | DEAD box helicase 20 | Enables histone deacetylase binding activity and protein-macromolecule adaptor activity. Involved in positive regulation of apoptotic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II; oogenesis; and regulation of steroid biosynthetic process. Part of RNA polymerase II transcription repressor complex. Is expressed in several structures, including brain; branchial arch; genitourinary system; hemolymphoid system; and liver. Orthologous to human DDX20 (DEAD-box helicase 20). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 105585586 | 105595104 | Mouse | 150 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8710866 | Ddx20 | DEAD-box helicase 20 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); histone deacetylase binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (or tholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN cytosol (ortholog); nuclear body (ortholog); nucleoplasm (ortholog) | NW_004955435 | 15209640 | 15219698 | Chinchilla | 33 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12021185 | DDX20 | DEAD-box helicase 20 | ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WIT H amyotrophic lateral sclerosis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); Gemini of Cajal bodies (inferred) | 1 | 114402492 | 114432217 | Bonobo | 50 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12108787 | DDX20 | DEAD-box helicase 20 | ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WIT H amyotrophic lateral sclerosis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); Gemini of Cajal bodies (inferred) | 17 | 63676146 | 63687503 | Dog | 54 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12466141 | Ddx20 | DEAD-box helicase 20 | ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WIT H amyotrophic lateral sclerosis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); Gemini of Cajal bodies (inferred) | NW_004936690 | 400563 | 413488 | Squirrel | 50 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18914350 | Ddx20 | DEAD-box helicase 20 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); histone deacetylase binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (or tholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); RNA polymerase II transcription repressor complex (ortholog) | | | | Naked Mole-Rat | 50 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18416928 | DDX20 | DEAD-box helicase 20 | ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WIT H amyotrophic lateral sclerosis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); Gemini of Cajal bodies (inferred) | | | | Green Monkey | 50 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13857230 | DDX20 | DEAD-box helicase 20 | ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WIT H amyotrophic lateral sclerosis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); Gemini of Cajal bodies (inferred); INTERACTS WITH ammonia; cadmium atom; deoxynivalenol | | | | Pig | 58 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 625898908 | Ddx20 | DEAD-box helicase 20 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); histone deacetylase binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (or tholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN cytosol (ortholog); nuclear body (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 33 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155257714 | ddx20 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155259878 | ddx20.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 7175934 | DDX20P1 | DEAD-box helicase 20 pseudogene 1 | | 10 | 147830 | 148796 | Human | | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1322484 | GEMIN6 | gem nuclear organelle associated protein 6 | GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1; MIM 602595), GEMIN3 (DDX20 weight:700;'>DDX20; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).[supplied by OMIM, Jul 2002] | 2 | 38778210 | 38785002 | Human | 125 | description | gene, protein-coding, VALIDATED [RefSeq] |