| 1308710 | Crim1 | cysteine rich transmembrane BMP regulator 1 | ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of osteoblast differentiation (ortholog); FOUND IN extracellular region (inferred); membrane (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 17 beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 22447983 | 22622459 | Rat | 150 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1318641 | CRIM1 | cysteine rich transmembrane BMP regulator 1 | This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010] | 2 | 36355778 | 36551135 | Human | 156 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1318642 | Crim1 | cysteine rich transmembrane BMP regulator 1 | Predicted to enable PDZ domain binding activity. Predicted to act upstream of or within negative regulation of BMP signaling pathway. Predicted to be located in extracellular region and membrane. Is expressed in several structures, including central nervous system; genitourinary system; heart; integ umental system; and sensory organ. Orthologous to human CRIM1 (cysteine rich transmembrane BMP regulator 1). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 78507602 | 78684021 | Mouse | 255 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8976072 | Crim1 | cysteine rich transmembrane BMP regulator 1 | ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of osteoblast differentiation (ortholog) | NW_004955441 | 4275411 | 4420537 | Chinchilla | 3 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11817189 | CRIM1 | cysteine rich transmembrane BMP regulator 1 | ENCODES a protein that exhibits enzyme inhibitor activity (inferred); PDZ domain binding (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of osteoblast differentiation (ortholog); FOUND IN ex tracellular region (inferred); plasma membrane (inferred) | 2A | 36384964 | 36580214 | Bonobo | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12178077 | CRIM1 | cysteine rich transmembrane BMP regulator 1 | ENCODES a protein that exhibits enzyme inhibitor activity (inferred); PDZ domain binding (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of osteoblast differentiation (ortholog); FOUND IN ex tracellular region (inferred); membrane (inferred) | 17 | 28857702 | 29042399 | Dog | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12615425 | Crim1 | cysteine rich transmembrane BMP regulator 1 | ENCODES a protein that exhibits enzyme inhibitor activity (inferred); PDZ domain binding (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of osteoblast differentiation (ortholog); FOUND IN ex tracellular region (inferred); membrane (inferred); plasma membrane (inferred) | NW_004936663 | 1623655 | 1803442 | Squirrel | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18615056 | CRIM1 | cysteine rich transmembrane BMP regulator 1 | ENCODES a protein that exhibits enzyme inhibitor activity (inferred); PDZ domain binding (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of osteoblast differentiation (ortholog); FOUND IN ex tracellular region (inferred); membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237569 | crim1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13989774 | CRIM1 | cysteine rich transmembrane BMP regulator 1 | ENCODES a protein that exhibits enzyme inhibitor activity (inferred); PDZ domain binding (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of osteoblast differentiation (ortholog); FOUND IN ex tracellular region (inferred); membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18914260 | Crim1 | cysteine rich transmembrane BMP regulator 1 | ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of osteoblast differentiation (ortholog); FOUND IN extracellular region (inferred); membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625956637 | Crim1 | cysteine rich transmembrane BMP regulator 1 | ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of osteoblast differentiation (ortholog) | | | | Black Rat | 3 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237568 | crim1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864564 | crim1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626179726 | crim1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857976 | crim1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864035 | crim1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857304 | crim1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626181001 | crim1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 13793245 | CRIM1-DT | CRIM1 divergent transcript | INTERACTS WITH 17beta-estradiol; lipopolysaccharide; S-(1,2-dichlorovinyl)-L-cysteine | 2 | 36354749 | 36355570 | Human | 4 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |