| 1306804 | Creg1 | cellular repressor of E1A-stimulated genes 1 | ENCODES a protein that exhibits insulin-like growth factor receptor binding (ortholog); INVOLVED IN autophagy (ortholog); endocytosis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH COVID-19 (ortholog); diastolic heart failure (ortholog); Prostatic Neoplasms (ortholog); FOUND I N endosome (ortholog); extracellular space (ortholog); lysosome (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 13 | 80552779 | 80565272 | Rat | 172 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1348156 | CREG1 | cellular repressor of E1A stimulated genes 1 | The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008] | 1 | 167541013 | 167553762 | Human | 177 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1558375 | Creg1 | cellular repressor of E1A-stimulated genes 1 | Predicted to enable insulin-like growth factor receptor binding activity. Acts upstream of or within several processes, including endocytosis; lysosomal lumen acidification; and regulation of DNA-templated transcription. Located in endosome and lysosome. Part of transcription regulator complex. Is e xpressed in central nervous system; liver; and ureter. Orthologous to human CREG1 (cellular repressor of E1A stimulated genes 1). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 165591327 | 165602878 | Mouse | 198 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8706926 | Creg1 | cellular repressor of E1A stimulated genes 1 | ENCODES a protein that exhibits insulin-like growth factor receptor binding (ortholog); INVOLVED IN autophagy (ortholog); endocytosis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH COVID-19 (ortholog); diastolic heart failure (ortholog); Prostatic Neoplasms (ortholog); FOUND I N endosome (ortholog); extracellular space (ortholog); lysosome (ortholog) | NW_004955462 | 9440019 | 9451875 | Chinchilla | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11988662 | CREG1 | cellular repressor of E1A stimulated genes 1 | ENCODES a protein that exhibits insulin-like growth factor receptor binding (inferred); INVOLVED IN autophagy (ortholog); endocytosis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH COVID-19 (ortholog); diastolic heart failure (ortholog); Prostatic Neoplasms (ortholog); FOUND I N cytoplasm (inferred); endomembrane system (inferred); endosome (inferred) | 1 | 142974260 | 142987071 | Bonobo | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12427147 | CREG1 | cellular repressor of E1A stimulated genes 1 | ENCODES a protein that exhibits insulin-like growth factor receptor binding (inferred); INVOLVED IN autophagy (ortholog); endocytosis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH COVID-19 (ortholog); diastolic heart failure (ortholog); Prostatic Neoplasms (ortholog); FOUND I N cytoplasm (inferred); endomembrane system (inferred); endosome (inferred) | 7 | 30873556 | 30884257 | Dog | 22 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12652199 | Creg1 | cellular repressor of E1A stimulated genes 1 | ENCODES a protein that exhibits insulin-like growth factor receptor binding (ortholog); INVOLVED IN autophagy (ortholog); endocytosis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH COVID-19 (ortholog); diastolic heart failure (ortholog); Prostatic Neoplasms (ortholog); FOUND I N endosome (ortholog); lysosome (ortholog); transcription regulator complex (ortholog) | NW_004936481 | 18523022 | 18531227 | Squirrel | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625952954 | Creg1 | cellular repressor of E1A stimulated genes 1 | ENCODES a protein that exhibits insulin-like growth factor receptor binding (ortholog); INVOLVED IN autophagy (ortholog); endocytosis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH COVID-19 (ortholog); diastolic heart failure (ortholog); Prostatic Neoplasms (ortholog); FOUND I N endosome (ortholog); extracellular space (ortholog); lysosome (ortholog) | | | | Black Rat | 19 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14128312 | CREG1 | cellular repressor of E1A stimulated genes 1 | ENCODES a protein that exhibits identical protein binding (inferred); insulin-like growth factor receptor binding (inferred); MHC class II receptor activity (inferred); INVOLVED IN autophagy (ortholog); endocytosis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH COVID-19 (ortho log); diastolic heart failure (ortholog); Prostatic Neoplasms (ortholog); FOUND IN alpha-beta T cell receptor complex (inferred); cytoplasm (inferred); endomembrane system (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 46 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18936607 | Creg1 | cellular repressor of E1A stimulated genes 1 | ENCODES a protein that exhibits insulin-like growth factor receptor binding (ortholog); INVOLVED IN autophagy (ortholog); endocytosis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH COVID-19 (ortholog); diastolic heart failure (ortholog); Prostatic Neoplasms (ortholog); FOUND I N endosome (ortholog); lysosome (ortholog); transcription regulator complex (ortholog) | | | | Naked Mole-Rat | 23 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18444730 | CREG1 | cellular repressor of E1A stimulated genes 1 | ENCODES a protein that exhibits insulin-like growth factor receptor binding (inferred); INVOLVED IN autophagy (ortholog); endocytosis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH COVID-19 (ortholog); diastolic heart failure (ortholog); Prostatic Neoplasms (ortholog); FOUND I N cytoplasm (inferred); endomembrane system (inferred); endosome (inferred) | | | | Green Monkey | 22 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155234928 | creg1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155234927 | creg1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 13290320 | LOC111091317 | protein CREG1-like | | 20 | 37178908 | 37180466 | Dog | | name | gene, pseudo, MODEL [RefSeq] |