| 1309678 | Colec11 | collectin sub-family member 11 | ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent carbohydrate binding (ortholog); D-mannose binding (ortholog); INVOLVED IN antimicrobial humoral response (ortholog); complement activation (ortholog); complement activation, lectin pathway (ortholog); PARTICIPATES IN phagocytosis pathway; ASSOCIATED WITH 3MC syndrome (ortholog); 3MC syndrome 1 (ortholog); 3MC syndrome 2 (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; indometacin | 6 | 50952357 | 50984845 | Rat | 94 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1320152 | COLEC11 | collectin subfamily member 11 | This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating t heir recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] | 2 | 3595112 | 3644644 | Human | 211 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320153 | Colec11 | collectin sub-family member 11 | This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating t heir recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in the human gene are a cause of 3MC syndrome-2. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015] | 12 | 28644171 | 28673458 | Mouse | 107 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8751217 | Colec11 | collectin subfamily member 11 | ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent carbohydrate binding (ortholog); D-mannose binding (ortholog); INVOLVED IN antimicrobial humoral response (ortholog); complement activation (ortholog); complement activation, lectin pathway (ortholog); ASSOCIATED WITH 3MC syndrome (ortholog); 3MC syndrome 1 (ortholog); 3MC syndrome 2 (ortholog); FOUND IN extracellular space (ortholog) | NW_004955487 | 3778901 | 3789852 | Chinchilla | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11834101 | COLEC11 | collectin subfamily member 11 | ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent carbohydrate binding (inferred); carbohydrate binding (inferred); INVOLVED IN antimicrobial humoral response (inferred); complement activation (inferred); complement activation, lectin pathway (inferred); ASSOCIATED WI TH 3MC syndrome (ortholog); 3MC syndrome 1 (ortholog); 3MC syndrome 2 (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 2A | 3610679 | 3659739 | Bonobo | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12321274 | COLEC11 | collectin subfamily member 11 | ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent carbohydrate binding (inferred); carbohydrate binding (inferred); INVOLVED IN antimicrobial humoral response (inferred); complement activation (inferred); complement activation, lectin pathway (inferred); ASSOCIATED WI TH 3MC syndrome (ortholog); 3MC syndrome 1 (ortholog); 3MC syndrome 2 (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 17 | 2147679 | 2180096 | Dog | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12688315 | Colec11 | collectin subfamily member 11 | ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent carbohydrate binding (inferred); carbohydrate binding (inferred); INVOLVED IN antimicrobial humoral response (inferred); complement activation (inferred); complement activation, lectin pathway (inferred); ASSOCIATED WI TH 3MC syndrome (ortholog); 3MC syndrome 1 (ortholog); 3MC syndrome 2 (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | NW_004936532 | 1757288 | 1776053 | Squirrel | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18679540 | COLEC11 | collectin subfamily member 11 | ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent carbohydrate binding (inferred); carbohydrate binding (inferred); INVOLVED IN antimicrobial humoral response (inferred); complement activation (inferred); complement activation, lectin pathway (inferred); ASSOCIATED WI TH 3MC syndrome (ortholog); 3MC syndrome 1 (ortholog); 3MC syndrome 2 (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Green Monkey | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18901137 | Colec11 | collectin subfamily member 11 | ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent carbohydrate binding (ortholog); DNA binding (ortholog); INVOLVED IN antimicrobial humoral response (ortholog); complement activation (ortholog); complement activation, lectin pathway (ortholog); ASSOCIATED WITH 3MC sy ndrome (ortholog); 3MC syndrome 1 (ortholog); 3MC syndrome 2 (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Naked Mole-Rat | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232017 | colec11 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14216680 | COLEC11 | collectin subfamily member 11 | ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent carbohydrate binding (inferred); carbohydrate binding (inferred); INVOLVED IN antimicrobial humoral response (inferred); complement activation (inferred); complement activation, lectin pathway (inferred); ASSOCIATED WI TH 3MC syndrome (ortholog); 3MC syndrome 1 (ortholog); 3MC syndrome 2 (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Pig | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626124745 | Colec11 | collectin subfamily member 11 | ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent carbohydrate binding (ortholog); D-mannose binding (ortholog); INVOLVED IN antimicrobial humoral response (ortholog); complement activation (ortholog); complement activation, lectin pathway (ortholog); ASSOCIATED WITH 3MC syndrome (ortholog); 3MC syndrome 1 (ortholog); 3MC syndrome 2 (ortholog); FOUND IN extracellular space (ortholog) | | | | Black Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232016 | colec11.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934350 | colec11.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934534 | colec11.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 596933949 | colec11.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155239130 | colec11.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 596935057 | colec11.S | | | | | | African Clawed Frog | | symbol | gene, null |
