| 1309165 | Cldn14 | claudin 14 | ENCODES a protein that exhibits structural molecule activity (inferred); INVOLVED IN response to ethanol (inferred); PARTICIPATES IN hepatitis C pathway; ASSOCIATED WITH Acidoses; autosomal recessive nonsyndromic deafness 29 (ortholog); Deafness (ortholog); FOUND IN bicellular tight junction (orthol og); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acetamide | 11 | 46701940 | 46799049 | Rat | 105 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1319353 | CLDN14 | claudin 14 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of cont inuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010] | 21 | 36460621 | 36576569 | Human | 109 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1319354 | Cldn14 | claudin 14 | This gene encodes a member of the claudin family of tight junction proteins. The encoded protein is an integral membrane protein that may function in maintaining apical membrane polarization in tight junctions located between outer hair cells and supporting cells. Loss of function of this gene is as sociated with hearing problems. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] | 16 | 93715919 | 93809733 | Mouse | 110 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8876498 | Cldn14 | claudin 14 | ASSOCIATED WITH Acidoses (ortholog); autosomal recessive nonsyndromic deafness 29 (ortholog); Deafness (ortholog); FOUND IN bicellular tight junction (ortholog); plasma membrane (ortholog) | NW_004955407 | 35641560 | 35728105 | Chinchilla | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11852122 | CLDN14 | claudin 14 | ENCODES a protein that exhibits structural molecule activity (inferred); ASSOCIATED WITH Acidoses (ortholog); autosomal recessive nonsyndromic deafness 29 (ortholog); Deafness (ortholog); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred) | 21 | 22830770 | 22946594 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12251923 | CLDN14 | claudin 14 | ENCODES a protein that exhibits structural molecule activity (inferred); ASSOCIATED WITH Acidoses (ortholog); autosomal recessive nonsyndromic deafness 29 (ortholog); Deafness (ortholog); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred) | 31 | 31677410 | 31725794 | Dog | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12679728 | Cldn14 | claudin 14 | ENCODES a protein that exhibits structural molecule activity (inferred); ASSOCIATED WITH Acidoses (ortholog); autosomal recessive nonsyndromic deafness 29 (ortholog); Deafness (ortholog); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred) | NW_004936500 | 6207856 | 6227582 | Squirrel | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18752657 | CLDN14 | claudin 14 | ENCODES a protein that exhibits structural molecule activity (inferred); ASSOCIATED WITH Acidoses (ortholog); autosomal recessive nonsyndromic deafness 29 (ortholog); Deafness (ortholog); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625864165 | Cldn14 | claudin 14 | ASSOCIATED WITH Acidoses (ortholog); autosomal recessive nonsyndromic deafness 29 (ortholog); Deafness (ortholog); FOUND IN bicellular tight junction (ortholog); plasma membrane (ortholog) | | | | Black Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13940257 | CLDN14 | claudin 14 | ENCODES a protein that exhibits structural molecule activity (inferred); ASSOCIATED WITH Acidoses (ortholog); autosomal recessive nonsyndromic deafness 29 (ortholog); Deafness (ortholog); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred) | | | | Pig | 19 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18926257 | Cldn14 | claudin 14 | ENCODES a protein that exhibits structural molecule activity (inferred); ASSOCIATED WITH Acidoses (ortholog); autosomal recessive nonsyndromic deafness 29 (ortholog); Deafness (ortholog); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155247013 | cldn14 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155245882 | cldn14.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155247012 | cldn14.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38637361 | CLDN14-AS1 | CLDN14 antisense RNA 1 | | 21 | 36430325 | 36498526 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 155791660 | LNCTSI | lncRNA TGF-beta/SMAD3 pathway interacting | | | | | Human | | old_gene_symbol | gene, ncrna |
