| 1307819 | Cela3b | chymotrypsin like elastase 3B | ENCODES a protein that exhibits endopeptidase activity (inferred); hydrolase activity (inferred); peptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH exocrine pancreatic insufficiency (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; bisphenol A | 5 | 154912170 | 154920333 | Rat | 48 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1317234 | CELA3B | chymotrypsin like elastase 3B | Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the h uman elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq, May 2009] | 1 | 21977022 | 21998642 | Human | 51 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1317235 | Cela3b | chymotrypsin-like elastase family, member 3B | Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Located in collagen-containing extracellular matrix. Is expressed in pancreas and pancreas tip epithelium. Orthologous to several human genes including CELA3B (chymo trypsin like elastase 3B). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 137148319 | 137157831 | Mouse | 49 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8976113 | Cela3b | chymotrypsin like elastase 3B | ASSOCIATED WITH exocrine pancreatic insufficiency (ortholog) | NW_004955452 | 2190177 | 2194453 | Chinchilla | 1 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155244882 | cela3b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18524661 | CELA3B | chymotrypsin like elastase 3B | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH exocrine pancreatic insufficiency (ortholog); FOUND IN extracellular space (inferred) | | | | Green Monkey | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18929073 | Cela3b | chymotrypsin like elastase 3B | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine hydrolase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH exocrine pancreatic insufficiency (ortholog); FOUND IN extracellular space (inferred) | | | | Naked Mole-Rat | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237798 | cela3b.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 12495396 | LOC101958816 | chymotrypsin-like elastase family member 3B | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine hydrolase activity (inferred); INVOLVED IN proteolysis (inferred); FOUND IN extracellular space (inferred) | NW_004936474 | 7528292 | 7534170 | Squirrel | 10 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12350646 | LOC478196 | proproteinase E | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH exocrine pancreatic insufficiency (ortholog) | 2 | 77223095 | 77228755 | Dog | 10 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 2295775 | Cela3a | chymotrypsin-like elastase family, member 3A | Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Orthologous to several human genes including CELA3B (chymotrypsin like elastase 3B). [provided by Alliance of Genome R esources, Jul 2025] | 4 | 137128865 | 137137102 | Mouse | 14 | description | gene, protein-coding, VALIDATED [RefSeq] |