| 619741 | Cdh10 | cadherin 10 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN synaptic membrane adhesion (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN GABA-ergic synapse; glutamatergic synapse; postsynaptic specialization membrane; INTERACTS WI TH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 2 | 70355521 | 70577880 | Rat | 104 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 736212 | Cdh10 | cadherin 10 | This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. This gene is expressed in the blood-brain barrier an d retinal endothelia suggesting a role in the development and maintenance of brain barrier. Alternative splicing results in multiple transcript variants. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 15. [provided by RefSeq, Oct 2015] | 15 | 18818763 | 19014883 | Mouse | 114 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 1350088 | CDH10 | cadherin 10 | This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral memb rane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. Mutations in this gene may be associated with lung squamous cell carcinoma and colorectal cancer in human patients. [provided by RefSeq, Nov 2015] | 5 | 24487100 | 24644978 | Human | 105 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8849085 | Cdh10 | cadherin 10 | INVOLVED IN synaptic membrane adhesion (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); postsynaptic specialization membrane (ortholog) | NW_004955426 | 11803669 | 11974051 | Chinchilla | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11860662 | CDH10 | cadherin 10 | ENCODES a protein that exhibits beta-catenin binding (inferred); cadherin binding (inferred); calcium ion binding (inferred); INVOLVED IN adherens junction organization (inferred); calcium-dependent cell-cell adhesion (inferred); cell adhesion (inferred); ASSOCIATED WITH autism spectrum disorder (or tholog); autistic disorder (ortholog); FOUND IN GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); postsynaptic specialization membrane (ortholog) | 5 | 85746559 | 85905904 | Bonobo | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12235025 | CDH10 | cadherin 10 | ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cell adhesion (inferred); cell-cell adhesion (inferred); homophilic cell-cell adhesion (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN GAB A-ergic synapse (ortholog); postsynaptic specialization membrane (ortholog); presynaptic active zone membrane (ortholog) | 4 | 80927251 | 81101053 | Dog | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626123917 | Cdh10 | cadherin 10 | INVOLVED IN synaptic membrane adhesion (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); postsynaptic specialization membrane (ortholog) | | | | Black Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13852645 | CDH10 | cadherin 10 | ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cell adhesion (inferred); cell-cell adhesion (inferred); homophilic cell-cell adhesion (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN GAB A-ergic synapse (ortholog); postsynaptic specialization membrane (ortholog); presynaptic active zone membrane (ortholog) | | | | Pig | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155260104 | cdh10 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18899773 | Cdh10 | cadherin 10 | ENCODES a protein that exhibits beta-catenin binding (inferred); cadherin binding (inferred); calcium ion binding (inferred); INVOLVED IN adherens junction organization (inferred); calcium-dependent cell-cell adhesion (inferred); cell adhesion (inferred); ASSOCIATED WITH autism spectrum disorder (or tholog); autistic disorder (ortholog); FOUND IN GABA-ergic synapse (ortholog); postsynaptic specialization membrane (ortholog); presynaptic active zone membrane (ortholog) | | | | Naked Mole-Rat | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18430079 | CDH10 | cadherin 10 | ENCODES a protein that exhibits beta-catenin binding (inferred); cadherin binding (inferred); calcium ion binding (inferred); INVOLVED IN adherens junction organization (inferred); calcium-dependent cell-cell adhesion (inferred); cell adhesion (inferred); ASSOCIATED WITH autism spectrum disorder (or tholog); autistic disorder (ortholog); FOUND IN GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); postsynaptic specialization membrane (ortholog) | | | | Green Monkey | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626182028 | cdh10.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859446 | cdh10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405865112 | cdh10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858063 | cdh10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863098 | cdh10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626468089 | cdh10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 12554737 | LOC101962167 | cadherin-10 | ENCODES a protein that exhibits beta-catenin binding (inferred); cadherin binding (inferred); calcium ion binding (inferred); INVOLVED IN adherens junction organization (inferred); calcium-dependent cell-cell adhesion (inferred); cell adhesion (inferred); ASSOCIATED WITH autism spectrum disorder (or tholog); autistic disorder (ortholog); FOUND IN GABA-ergic synapse (ortholog); postsynaptic specialization membrane (ortholog); presynaptic active zone membrane (ortholog) | NW_004936811 | 386933 | 547222 | Squirrel | 29 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |