| 12338063 | CDK11 | cyclin dependent kinase 11 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase activity (ortholog); RNA polymerase II CTD heptapeptide repeat S2 kinase activity (ortholog); RNA polymerase II CTD heptapeptide repeat S5 kinase activity (ortholog); INVOLVED IN blastocyst development (ortholog); mitot ic sister chromatid cohesion, centromeric (ortholog); negative regulation of apoptotic signaling pathway (ortholog); ASSOCIATED WITH Brachymorphism-Onychodysplasia-Dysphalangism Syndrome (ortholog); epilepsy (ortholog); FOUND IN chromosome (ortholog); chromosome, centromeric region (ortholog); cyclin L-CDK11 complex (ortholog) | 5 | 56698267 | 56714075 | Dog | 41 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 628604 | Cdk11b | cyclin-dependent kinase 11B | ENCODES a protein that exhibits ATP binding (ortholog); cyclin-dependent protein serine/threonine kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN blastocyst development (ortholog); mitotic sister chromatid cohesion, centromeric (ortholog); negative regula tion of apoptotic signaling pathway (ortholog); ASSOCIATED WITH Brachymorphism-Onychodysplasia-Dysphalangism Syndrome (ortholog); epilepsy (ortholog); FOUND IN chromosome (ortholog); chromosome, centromeric region (ortholog); cyclin L-CDK11 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 5 | 171495042 | 171521143 | Rat | 124 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 732629 | Cdk11b | cyclin dependent kinase 11B | Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Acts upstream of or within blastocyst development; negative regulation of apoptotic signaling pathway; and regulation of mitotic nuclear division. Located in nucleus. Is expressed in several structures, including alimentary system; brain; early embryo; integumental system; and submandibular gland primordium. Orthologous to several human genes including CDK11B (cyclin dependent kinase 11B). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 155709303 | 155734392 | Mouse | 118 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1604656 | CDK11B | cyclin dependent kinase 11B | This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently de leted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] | 1 | 1635225 | 1659004 | Human | 127 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |