| 1354337 | BRWD3 | bromodomain and WD repeat domain containing 3 | The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene are associated with a spectrum of cognitive disabilities and X-linked macrocephaly. This gene is als o associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, Jul 2017] | X | 80669503 | 80809877 | Human | 124 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1559445 | Brwd3 | bromodomain and WD repeat domain containing 3 | ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | X | 77843766 | 77937240 | Rat | 81 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1623671 | Brwd3 | bromodomain and WD repeat domain containing 3 | Predicted to be involved in cytoskeleton organization; regulation of cell shape; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 93. Orthologous to human BRWD3 font-weight:700;'>BRWD3 (bromodomain and WD repeat domain containing 3). [provided by Alliance of Genome Resources, Jul 2025] | X | 107779451 | 107877965 | Mouse | 91 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9011920 | Brwd3 | bromodomain and WD repeat domain containing 3 | ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog) | NW_004955529 | 834459 | 992259 | Chinchilla | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11708229 | BRWD3 | bromodomain and WD repeat domain containing 3 | INVOLVED IN cytoskeleton organization (inferred); regulation of cell shape (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred) | X | 69718532 | 69857507 | Bonobo | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12092238 | BRWD3 | bromodomain and WD repeat domain containing 3 | ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog) | X | 62004536 | 62180260 | Dog | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12546670 | Brwd3 | bromodomain and WD repeat domain containing 3 | INVOLVED IN cytoskeleton organization (inferred); regulation of cell shape (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred) | NW_004936547 | 2236164 | 2354652 | Squirrel | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14370323 | BRWD3 | | | | | | Fly | | symbol | gene, null |
| 18931915 | Brwd3 | bromodomain and WD repeat domain containing 3 | INVOLVED IN cytoskeleton organization (inferred); regulation of cell shape (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625889073 | Brwd3 | bromodomain and WD repeat domain containing 3 | ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog) | | | | Black Rat | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18509386 | BRWD3 | bromodomain and WD repeat domain containing 3 | INVOLVED IN cytoskeleton organization (inferred); regulation of cell shape (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14185423 | BRWD3 | bromodomain and WD repeat domain containing 3 | ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog) | | | | Pig | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231578 | brwd3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155231577 | brwd3.L | | | | | | African Clawed Frog | | symbol | gene, null |