ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN regulation of alternative mRNA splicing, via spliceosome (ortholog); synaptic transmission, serotonergic (ortholog); vocalization behavior (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH (S
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be invol
ved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
Predicted to enable mRNA binding activity. Acts upstream of or within serotonergic synaptic transmission and vocalization behavior. Located in cytoplasm. Is expressed in several structures, including central nervous system; neural ectoderm; sensory organ; stomach; and testis. Orthologous to human CE