| 1308512 | Bdp1 | BDP1 general transcription factor IIIB subunit | INVOLVED IN positive regulation of transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 112 (ortholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN nucleoplasm (ortholog); INTERA CTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acetamide | 2 | 33112518 | 33204270 | Rat | 79 | symbol , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1318324 | BDP1 | BDP1 general transcription factor IIIB subunit | The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three ty pes of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. [provided by RefSeq, Jul 2008] | 5 | 71455651 | 71578288 | Human | 91 | symbol , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1556946 | Bdp1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | Predicted to enable TFIIIC-class transcription factor complex binding activity. Predicted to be involved in RNA polymerase III preinitiation complex assembly. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be par t of transcription factor TFIIIB complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 112. Orthologous to human BDP1 (BDP1 general transcription factor IIIB subunit). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 100154502 | 100244524 | Mouse | 90 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8941266 | Bdp1 | BDP1 general transcription factor IIIB subunit | INVOLVED IN positive regulation of transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 112 (ortholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN nucleoplasm (ortholog); transc ription factor TFIIIB complex (ortholog) | NW_004955575 | 330683 | 430269 | Chinchilla | 10 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11933047 | BDP1 | BDP1 general transcription factor IIIB subunit | ENCODES a protein that exhibits TFIIIC-class transcription factor complex binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase III (inferred); RNA polymerase III preinitiation complex assembly (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASS OCIATED WITH autosomal recessive nonsyndromic deafness 112 (ortholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN nucleoplasm (inferred); transcription factor TFIIIB complex (inferred) | 5 | 43733861 | 43856941 | Bonobo | 12 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12317019 | BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | INVOLVED IN positive regulation of transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 112 (ortholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN nucleoplasm (ortholog) | 2 | 54654406 | 54743443 | Dog | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12737594 | Bdp1 | BDP1 general transcription factor IIIB subunit | INVOLVED IN positive regulation of transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 112 (ortholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN nucleoplasm (ortholog); transc ription factor TFIIIB complex (ortholog) | NW_004936549 | 4842004 | 4943399 | Squirrel | 10 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 625842136 | Bdp1 | BDP1 general transcription factor IIIB subunit | INVOLVED IN positive regulation of transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 112 (ortholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN nucleoplasm (ortholog); transc ription factor TFIIIB complex (ortholog) | | | | Black Rat | 10 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18932254 | Bdp1 | BDP1 general transcription factor IIIB subunit | ENCODES a protein that exhibits TFIIIC-class transcription factor complex binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 112 (or tholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Naked Mole-Rat | 12 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 286134143 | bdp1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14372197 | Bdp1 | | | | | | Fly | | symbol | gene, null |
| 14157359 | BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | INVOLVED IN positive regulation of transcription by RNA polymerase III (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 112 (ortholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN nucleoplasm (inferred) | | | | Pig | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14372199 | BDP1 | | | | | | Yeast | | symbol | gene, null |
| 18515170 | BDP1 | BDP1 general transcription factor IIIB subunit | ENCODES a protein that exhibits TFIIIC-class transcription factor complex binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase III (inferred); RNA polymerase III preinitiation complex assembly (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASS OCIATED WITH autosomal recessive nonsyndromic deafness 112 (ortholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN nucleoplasm (inferred); transcription factor TFIIIB complex (inferred) | | | | Green Monkey | 12 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 287162282 | bdp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284874217 | bdp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1323122 | PTPN18 | protein tyrosine phosphatase non-receptor type 18 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST moti f, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] | 2 | 130356056 | 130375405 | Human | 108 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 2289748 | BDP1P | B double prime 1 pseudogene | | 18 | 77432057 | 77437248 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
