This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosami
ne, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes a protein that functions in N-linked glycoprotein glycosylation and shows strict donor substrate specificity for UDP-galactose. [provided by RefSeq, Jul 2008]
ENCODES a protein that exhibits N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (ortholog); INVOLVED IN glucosylceramide metabolic process (ortholog); oligosaccharide biosynthetic process (ortholog); PARTICIPATES IN lacto-series glycosphingolipid metabolic pathway; FOUND IN G
Enables N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity. Acts upstream of or within oligosaccharide biosynthetic process. Predicted to be active in Golgi membrane. Is expressed in several structures, including alimentary system; brain; male reproductive gland or organ; respir
ENCODES a protein that exhibits N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (ortholog); INVOLVED IN glucosylceramide metabolic process (ortholog); oligosaccharide biosynthetic process (ortholog)
ENCODES a protein that exhibits glycosyltransferase activity (inferred); hexosyltransferase activity (inferred); N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (inferred); INVOLVED IN oligosaccharide biosynthetic process (ortholog); FOUND IN Golgi membrane (inferred); membra
ENCODES a protein that exhibits glycosyltransferase activity (inferred); hexosyltransferase activity (inferred); N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (inferred); INVOLVED IN oligosaccharide biosynthetic process (ortholog); FOUND IN Golgi membrane (inferred); membra
ENCODES a protein that exhibits glycosyltransferase activity (inferred); hexosyltransferase activity (inferred); N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (inferred); INVOLVED IN oligosaccharide biosynthetic process (ortholog); FOUND IN Golgi membrane (inferred); membra
ENCODES a protein that exhibits glycosyltransferase activity (inferred); hexosyltransferase activity (inferred); N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (inferred); INVOLVED IN oligosaccharide biosynthetic process (ortholog); FOUND IN Golgi membrane (inferred); membra
ENCODES a protein that exhibits glycosyltransferase activity (inferred); hexosyltransferase activity (inferred); N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (inferred); INVOLVED IN oligosaccharide biosynthetic process (ortholog); FOUND IN Golgi membrane (inferred); membra
ENCODES a protein that exhibits glycosyltransferase activity (inferred); hexosyltransferase activity (inferred); N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (inferred); INVOLVED IN glucosylceramide metabolic process (ortholog); oligosaccharide biosynthetic process (orthol
ENCODES a protein that exhibits N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (ortholog); INVOLVED IN glucosylceramide metabolic process (ortholog); oligosaccharide biosynthetic process (ortholog)