| 621393 | Atp6v0e1 | ATPase H+ transporting V0 subunit e1 | ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (ortholog); INVOLVED IN response to amino acid; proton transmembrane transport (ortholog); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN endomembrane system (inferred); membrane (inferred); proton-transporting V-type ATPase, V0 domain (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 10 | 16984084 | 17007156 | Rat | 104 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1350958 | ATP6V0E1 | ATPase H+ transporting V0 subunit e1 | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated en docytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is possibly part of the V0 subunit. Since two nontranscribed pseudogenes have been found in dog, it is possible that the localization to chromosome 2 for this gene by radiation hybrid mapping is representing a pseudogene. Genomic mapping puts the chromosomal location on 5q35.3. [provided by RefSeq, Jul 2008] | 5 | 172983771 | 173035445 | Human | 105 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8752072 | Atp6v0e1 | ATPase H+ transporting V0 subunit e1 | ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (ortholog); INVOLVED IN proton transmembrane transport (ortholog); response to amino acid (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog) | NW_004955408 | 25667703 | 25703550 | Chinchilla | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11786911 | ATP6V0E1 | ATPase H+ transporting V0 subunit e1 | ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN response to amino acid (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN membrane (inferred); proton-transporting V-type ATPase, V0 domain (inferred) | 5 | 168336845 | 168388230 | Bonobo | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12061647 | ATP6V0E1 | ATPase H+ transporting V0 subunit e1 | ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN response to amino acid (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN membrane (inferred); proton-transporting V-type ATPase, V0 domain (inferred) | 4 | 39378007 | 39409968 | Dog | 15 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12673263 | Atp6v0e1 | ATPase H+ transporting V0 subunit e1 | ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN response to amino acid (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN membrane (inferred); proton-transporting V-type ATPase, V0 domain (inferred) | NW_004936609 | 2510178 | 2533934 | Squirrel | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18915540 | Atp6v0e1 | ATPase H+ transporting V0 subunit e1 | ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN response to amino acid (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN membrane (inferred); proton-transporting V-type ATPase, V0 domain (inferred) | | | | Naked Mole-Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234237 | atp6v0e1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625859216 | Atp6v0e1 | ATPase H+ transporting V0 subunit e1 | ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (ortholog); INVOLVED IN proton transmembrane transport (ortholog); response to amino acid (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog) | | | | Black Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14241880 | ATP6V0E1 | ATPase H+ transporting V0 subunit e1 | ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN response to amino acid (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN membrane (inferred); proton-transporting V-type ATPase, V0 domain (inferred) | | | | Pig | 15 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18528961 | ATP6V0E1 | ATPase H+ transporting V0 subunit e1 | ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN response to amino acid (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN membrane (inferred); proton-transporting V-type ATPase, V0 domain (inferred) | | | | Green Monkey | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239918 | atp6v0e1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155234238 | atp6v0e1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1553358 | Atp6v0e | ATPase, H+ transporting, lysosomal V0 subunit E | Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Part of proton-transporting V-type ATPase complex. Is expressed in several structures, including alimentary system; cranium; heart; nervous system; and sensory o rgan. Orthologous to human ATP6V0E1 (ATPase H+ transporting V0 subunit e1). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 26895370 | 26918621 | Mouse | 97 | description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 6480947 | ATP6V0E1P1 | ATPase H+ transporting V0 subunit e1 pseudogene 1 | | 5 | 132948493 | 132948715 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 6480944 | ATP6V0E1P2 | ATPase H+ transporting V0 subunit e1 pseudogene 2 | | 3 | 41859154 | 41859641 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5132555 | ATP6V0E1P3 | ATPase H+ transporting V0 subunit e1 pseudogene 3 | | 2 | 33601983 | 33602785 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 6480943 | ATP6V0E1P4 | ATPase H+ transporting V0 subunit e1 pseudogene 4 | | 1 | 47550196 | 47550750 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |