| 1306571 | Arsg | arylsulfatase G | ENCODES a protein that exhibits arylsulfatase activity (ortholog); N-sulfoglucosamine-3-sulfatase activity (ortholog); INVOLVED IN gene expression (ortholog); glial cell differentiation (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); fundus dystrophy (ortholog); mucopolysaccharidosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog); lysosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 10 | 94912094 | 95063021 | Rat | 127 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1331908 | Arsg | arylsulfatase G | Enables N-sulfoglucosamine-3-sulfatase activity and arylsulfatase activity. Acts upstream of or within several processes, including lysosome organization; neuron apoptotic process; and retina development in camera-type eye. Located in lysosome. Is expressed in central nervous system and retina. Used to study mucopolysaccharidosis. Human ortholog(s) of this gene implicated in Usher syndrome. Orthologous to human ARSG (arylsulfatase G). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 109364159 | 109464156 | Mouse | 155 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1602225 | ARSG | arylsulfatase G | The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] | 17 | 68259170 | 68452019 | Human | 170 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8757184 | Arsg | arylsulfatase G | ENCODES a protein that exhibits arylsulfatase activity (ortholog); N-sulfoglucosamine-3-sulfatase activity (ortholog); INVOLVED IN gene expression (ortholog); glial cell differentiation (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); fundus dystrophy (ortholog); mucopolysaccharidosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog); lysosome (ortholog) | NW_004955478 | 4326669 | 4475559 | Chinchilla | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11921518 | ARSG | arylsulfatase G | ENCODES a protein that exhibits arylsulfatase activity (ortholog); INVOLVED IN gene expression (ortholog); glial cell differentiation (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); fundus dystrophy (ortholog); mucopolysaccharidosis (orthol og); FOUND IN endoplasmic reticulum (inferred); extracellular space (inferred); lysosome (inferred) | 17 | 62195977 | 62379362 | Bonobo | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12390961 | ARSG | arylsulfatase G | ENCODES a protein that exhibits arylsulfatase activity (ortholog); INVOLVED IN gene expression (ortholog); glial cell differentiation (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH neuronal ceroid lipofuscinosis; autism spectrum disorder (ortholog); fundus dystrophy (ortholog ); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog); lysosome (ortholog) | 9 | 15048563 | 15115095 | Dog | 33 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12623622 | Arsg | arylsulfatase G | ENCODES a protein that exhibits arylsulfatase activity (ortholog); INVOLVED IN gene expression (ortholog); glial cell differentiation (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); fundus dystrophy (ortholog); mucopolysaccharidosis (orthol og); FOUND IN endoplasmic reticulum (inferred); extracellular space (inferred); lysosome (inferred) | NW_004936541 | 7664241 | 7782762 | Squirrel | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18592155 | ARSG | arylsulfatase G | ENCODES a protein that exhibits arylsulfatase activity (ortholog); INVOLVED IN gene expression (ortholog); glial cell differentiation (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); fundus dystrophy (ortholog); mucopolysaccharidosis (orthol og); FOUND IN endoplasmic reticulum (inferred); extracellular space (inferred); lysosome (inferred) | | | | Green Monkey | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 286220646 | arsg | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13882461 | ARSG | arylsulfatase G | ENCODES a protein that exhibits arylsulfatase activity (ortholog); INVOLVED IN gene expression (ortholog); glial cell differentiation (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); fundus dystrophy (ortholog); mucopolysaccharidosis (orthol og); FOUND IN endoplasmic reticulum (inferred); extracellular space (inferred); lysosome (inferred); INTERACTS WITH deoxynivalenol; resveratrol | | | | Pig | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626081568 | Arsg | arylsulfatase G | ENCODES a protein that exhibits arylsulfatase activity (ortholog); N-sulfoglucosamine-3-sulfatase activity (ortholog); INVOLVED IN gene expression (ortholog); glial cell differentiation (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); fundus dystrophy (ortholog); mucopolysaccharidosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog); lysosome (ortholog) | | | | Black Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18909450 | Arsg | arylsulfatase G | ENCODES a protein that exhibits arylsulfatase activity (ortholog); INVOLVED IN gene expression (ortholog); glial cell differentiation (ortholog); homeostasis of number of cells (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); fundus dystrophy (ortholog); mucopolysaccharidosis (orthol og); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog) | | | | Naked Mole-Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 405860588 | arsg.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626177302 | arsg.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856536 | arsg.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862634 | arsg.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405860321 | arsg.L | | | | | | African Clawed Frog | | symbol | gene, null |