| 1305053 | Arhgap18 | Rho GTPase activating protein 18 | ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN regulation of actin cytoskeleton organization (ortholog); regulation of actin filament polymerization (ortholog); regulation of cell motility (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasm (or tholog); cytoplasmic microtubule (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine | 1 | 20222948 | 20456827 | Rat | 168 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1312852 | ARHGAP18 | Rho GTPase activating protein 18 | Enables GTPase activator activity. Involved in several processes, including regulation of actin filament polymerization; regulation of small GTPase mediated signal transduction; and small GTPase-mediated signal transduction. Located in cytosol; nuclear speck; and plasma membrane. Part of cytoplasmic microtubule and ruffle. Implicated in schizophrenia. [provided by Alliance of Genome Resources, Jul 2025] | 6 | 129576132 | 129710177 | Human | 160 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1312853 | Arhgap18 | Rho GTPase activating protein 18 | Enables GTPase activator activity. Predicted to be involved in several processes, including regulation of actin filament polymerization; regulation of small GTPase mediated signal transduction; and small GTPase-mediated signal transduction. Predicted to be located in several cellular components, inc luding cytoplasmic microtubule; nuclear speck; and ruffle. Predicted to be active in cytoplasm. Is expressed in lower leg bone. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human ARHGAP18 (Rho GTPase activating protein 18). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 26648363 | 26794644 | Mouse | 190 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8922882 | Arhgap18 | Rho GTPase activating protein 18 | ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN regulation of actin cytoskeleton organization (ortholog); regulation of actin filament polymerization (ortholog); regulation of cell motility (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasm (or tholog); cytoplasmic microtubule (ortholog); cytosol (ortholog) | NW_004955436 | 10470398 | 10642890 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11986070 | ARHGAP18 | Rho GTPase activating protein 18 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of actin cytoskeleton organization (inferred); regulation of actin filament polymerization (inferred); regulation of cell motility (inferred); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasm (in ferred); cytoplasmic microtubule (inferred); cytosol (inferred) | 6 | 127368377 | 127558136 | Bonobo | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12311155 | ARHGAP18 | Rho GTPase activating protein 18 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of actin cytoskeleton organization (inferred); regulation of actin filament polymerization (inferred); regulation of cell motility (inferred); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasm (in ferred); cytoplasmic microtubule (inferred); cytosol (inferred) | 1 | 68143702 | 68262440 | Dog | 20 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12668967 | Arhgap18 | Rho GTPase activating protein 18 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of actin cytoskeleton organization (inferred); regulation of actin filament polymerization (inferred); regulation of cell motility (inferred); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasm (in ferred); cytoplasmic microtubule (inferred); cytosol (inferred) | NW_004936639 | 68321 | 186169 | Squirrel | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626025337 | Arhgap18 | Rho GTPase activating protein 18 | ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN regulation of actin cytoskeleton organization (ortholog); regulation of actin filament polymerization (ortholog); regulation of cell motility (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasm (or tholog); cytoplasmic microtubule (ortholog); cytosol (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14117790 | ARHGAP18 | Rho GTPase activating protein 18 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of actin cytoskeleton organization (inferred); regulation of actin filament polymerization (inferred); regulation of cell motility (inferred); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasm (in ferred); cytoplasmic microtubule (inferred); cytosol (inferred) | | | | Pig | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18928437 | Arhgap18 | Rho GTPase activating protein 18 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of actin cytoskeleton organization (ortholog); regulation of cell motility (ortholog); regulation of cell shape (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasmic microtubule (ortholo g); cytosol (ortholog); ruffle (ortholog) | | | | Naked Mole-Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155240694 | arhgap18 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18463063 | ARHGAP18 | Rho GTPase activating protein 18 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of actin cytoskeleton organization (inferred); regulation of actin filament polymerization (inferred); regulation of cell motility (inferred); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN cytoplasm (in ferred); cytoplasmic microtubule (inferred); cytosol (inferred) | | | | Green Monkey | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237491 | arhgap18.L | | | | | | African Clawed Frog | | symbol | gene, null |
