| 620004 | Angptl2 | angiopoietin-like 2 | INVOLVED IN blood coagulation (inferred); ASSOCIATED WITH dermatomyositis (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 36914876 | 36944715 | Rat | 124 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 733949 | ANGPTL2 | angiopoietin like 2 | Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 prot ein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008] | 9 | 127087348 | 127122635 | Human | 129 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 733950 | Angptl2 | angiopoietin-like 2 | Predicted to enable signaling receptor binding activity. Predicted to be involved in blood coagulation. Located in extracellular space. Is expressed in several structures, including brain; intraembryonic coelom; limb segment; meninges; and skeleton. Used to study dermatomyositis. Orthologous to huma n ANGPTL2 (angiopoietin like 2). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 33105963 | 33137737 | Mouse | 132 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8739935 | Angptl2 | angiopoietin like 2 | ASSOCIATED WITH dermatomyositis (ortholog) | NW_004955419 | 1417773 | 1450199 | Chinchilla | 2 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11898037 | ANGPTL2 | angiopoietin like 2 | INVOLVED IN blood coagulation (inferred); ASSOCIATED WITH dermatomyositis (ortholog); FOUND IN extracellular region (inferred) | 9 | 98206703 | 98242169 | Bonobo | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12217844 | ANGPTL2 | angiopoietin like 2 | INVOLVED IN angiogenesis (inferred); blood coagulation (inferred); ASSOCIATED WITH dermatomyositis (ortholog); FOUND IN extracellular region (inferred) | 9 | 56184298 | 56220309 | Dog | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12619770 | Angptl2 | angiopoietin like 2 | INVOLVED IN blood coagulation (inferred); ASSOCIATED WITH dermatomyositis (ortholog); FOUND IN extracellular region (inferred) | NW_004936487 | 14889533 | 14923265 | Squirrel | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626124382 | Angptl2 | angiopoietin like 2 | ASSOCIATED WITH dermatomyositis (ortholog) | | | | Black Rat | 2 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18936006 | Angptl2 | angiopoietin like 2 | INVOLVED IN blood coagulation (inferred); ASSOCIATED WITH dermatomyositis (ortholog); FOUND IN extracellular region (inferred) | | | | Naked Mole-Rat | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237357 | angptl2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14282804 | ANGPTL2 | angiopoietin like 2 | INVOLVED IN angiogenesis (inferred); blood coagulation (inferred); ASSOCIATED WITH dermatomyositis (ortholog); FOUND IN extracellular region (inferred) | | | | Pig | 8 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18479954 | ANGPTL2 | angiopoietin like 2 | INVOLVED IN blood coagulation (inferred); ASSOCIATED WITH dermatomyositis (ortholog); FOUND IN extracellular region (inferred) | | | | Green Monkey | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237356 | angptl2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155238618 | angptl2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1344384 | ANGPTL4 | angiopoietin like 4 | This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also ac t as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013] | 19 | 8364155 | 8374370 | Human | 445 | description , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |