| 1310046 | Adamts16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN male gamete generation; regulation of cilium assembly; regulation of systemic arterial blood pressure; ASSOCIATED WITH decreased systemic arterial blood pressure; decreased systemic arterial diastolic blood pressure; decreased systemic arterial systolic blood pressure; ASSOCIATED WITH cryptorchidism; hypertension; male infertility; INTERACTS WITH alpha-Zearalanol; bisphenol A; paracetamol | 1 | 34258899 | 34388952 | Rat | 69 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1320722 | ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (T S) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may inhibit chondrosarcoma cell proliferation and migration. This gene may regulate blood pressure. [provided by RefSeq, May 2016] | 5 | 5140330 | 5320304 | Human | 64 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1320723 | Adamts16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is co-expressed with the Wilms tumor protein, Wt1, in the developing glomeruli of embryonic kidneys. The encoded preproprotein undergoes proteolytic processing to generate an active enzyme. [provided by RefSeq, Jul 2016] | 13 | 70875917 | 70989956 | Mouse | 77 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8788712 | Adamts16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); male gamete generation (ortholog); regulation of cilium assembly (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); cryptorchidism (ortholog); hypertension (ortholog) | NW_004955504 | 3167142 | 3320632 | Chinchilla | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11939904 | ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); male gamete generation (ortholog); regulation of cilium assembly (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); cryptorchidism (ortholog); hypertension (ortholog); FOUND IN extracellular matrix (inferred) | 5 | 5470841 | 5651360 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12331989 | ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); male gamete generation (ortholog); regulation of cilium assembly (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); cryptorchidism (ortholog); hypertension (ortholog) | 34 | 8196733 | 8346215 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12659680 | Adamts16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); male gamete generation (ortholog); regulation of cilium assembly (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); cryptorchidism (ortholog); hypertension (ortholog); FOUND IN extracellular matrix (inferred) | NW_004936634 | 1830252 | 1925622 | Squirrel | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13883122 | ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); male gamete generation (ortholog); regulation of cilium assembly (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); cryptorchidism (ortholog); hypertension (ortholog) | | | | Pig | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155233027 | adamts16 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18619613 | ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); male gamete generation (ortholog); regulation of cilium assembly (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); cryptorchidism (ortholog); hypertension (ortholog) | | | | Green Monkey | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625963733 | Adamts16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); male gamete generation (ortholog); regulation of cilium assembly (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); cryptorchidism (ortholog); hypertension (ortholog) | | | | Black Rat | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20867357 | ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN extracellular matrix organization (inferred); proteolysis (inferred); FOUND IN extracellular matrix (inferred) | | | | Green Monkey | 13 | symbol | gene, protein-coding |
| 18931597 | Adamts16 | ADAM metallopeptidase with thrombospondin type 1 motif 16 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); male gamete generation (ortholog); regulation of cilium assembly (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); cryptorchidism (ortholog); hypertension (ortholog); FOUND IN extracellular matrix (inferred) | | | | Naked Mole-Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155233028 | adamts16.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 16558921 | ADAMTS16-DT | ADAMTS16 divergent transcript | INTERACTS WITH triclosan; valproic acid | 5 | 5132085 | 5140054 | Human | 2 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 407570627 | ADAMTS16-AS1 | ADAMTS16 antisense RNA 1 | | 5 | 5142138 | 5176214 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 13437613 | Adamts16em1Bj | ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj | ASSOCIATED WITH decreased systemic arterial diastolic blood pressure; decreased systemic arterial systolic blood pressure; extended life span; ASSOCIATED WITH cryptorchidism; hypertension; male infertility | | | | Rat | 12 | symbol , old_gene_symbol | gene, allele |
| 1318082 | ADAMTS19 | ADAM metallopeptidase with thrombospondin type 1 motif 19 | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS ) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. [provided by RefSeq, Jul 2008] | 5 | 129460298 | 129738683 | Human | 104 | description | gene, protein-coding, REVIEWED [RefSeq] |