| 1308270 | Acp4 | acid phosphatase 4 | ENCODES a protein that exhibits protein tyrosine phosphatase activity (ortholog); receptor tyrosine kinase binding (ortholog); INVOLVED IN negative regulation of ERBB4 signaling pathway (ortholog); negative regulation of neuron projection development (ortholog); negative regulation of protein proces sing (ortholog); PARTICIPATES IN riboflavin metabolic pathway; ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta type 1J (ortholog); FOUND IN glutamatergic synapse; postsynaptic membrane; synaptic membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; C60 fullerene | 1 | 103872922 | 103888418 | Rat | 55 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1317948 | ACP4 | acid phosphatase 4 | Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits a lower level of expression in testicular cancer tissues than in normal t issues. The protein encoded by this gene has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] | 19 | 50790415 | 50795219 | Human | 61 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1616331 | Acp4 | acid phosphatase 4 | Predicted to enable acid phosphatase activity; protein tyrosine phosphatase activity; and receptor tyrosine kinase binding activity. Predicted to be involved in several processes, including negative regulation of ERBB4 signaling pathway; negative regulation of protein metabolic process; and regulati on of neuronal synaptic plasticity. Predicted to be located in membrane. Predicted to be active in lysosome and postsynaptic membrane. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J. Orthologous to human ACP4 (acid phosphatase 4). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 43901427 | 43910814 | Mouse | 62 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 9012606 | Acp4 | acid phosphatase 4 | ENCODES a protein that exhibits protein tyrosine phosphatase activity (ortholog); receptor tyrosine kinase binding (ortholog); INVOLVED IN negative regulation of ERBB4 signaling pathway (ortholog); negative regulation of neuron projection development (ortholog); negative regulation of protein proces sing (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta type 1J (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic membrane (ortholog); synaptic membrane (ortholog) | NW_004955559 | 481953 | 488464 | Chinchilla | 15 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 11854273 | ACP4 | acid phosphatase 4 | ENCODES a protein that exhibits acid phosphatase activity (inferred); hydrolase activity (inferred); phosphatase activity (inferred); INVOLVED IN peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); am elogenesis imperfecta type 1J (ortholog); FOUND IN glutamatergic synapse (ortholog); synaptic membrane (ortholog) | 19 | 47754780 | 47760294 | Bonobo | 25 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12333184 | ACP4 | acid phosphatase 4 | ENCODES a protein that exhibits acid phosphatase activity (inferred); hydrolase activity (inferred); protein tyrosine phosphatase activity (inferred); INVOLVED IN peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity (ortholog); ASSOCIATED WITH amelogenesis imperfec ta (ortholog); amelogenesis imperfecta type 1J (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic membrane (ortholog); synaptic membrane (ortholog) | 1 | 106051901 | 106056137 | Dog | 23 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12599814 | Acp4 | acid phosphatase 4 | ENCODES a protein that exhibits acid phosphatase activity (inferred); hydrolase activity (inferred); phosphatase activity (inferred); INVOLVED IN peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); am elogenesis imperfecta type 1J (ortholog); FOUND IN glutamatergic synapse (ortholog); synaptic membrane (ortholog) | NW_004936889 | 510667 | 515831 | Squirrel | 26 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14182058 | ACP4 | acid phosphatase 4 | ENCODES a protein that exhibits acid phosphatase activity (inferred); hydrolase activity (inferred); protein tyrosine phosphatase activity (inferred); INVOLVED IN peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity (ortholog); ASSOCIATED WITH amelogenesis imperfec ta (ortholog); amelogenesis imperfecta type 1J (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic membrane (ortholog); synaptic membrane (ortholog) | | | | Pig | 23 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18925384 | Acp4 | acid phosphatase 4 | ENCODES a protein that exhibits acid phosphatase activity (inferred); hydrolase activity (inferred); phosphatase activity (inferred); INVOLVED IN negative regulation of neuron projection development (ortholog); negative regulation of protein processing (ortholog); odontogenesis (ortholog); ASSOCIATE D WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta type 1J (ortholog); FOUND IN glutamatergic synapse (ortholog); synaptic membrane (ortholog) | | | | Naked Mole-Rat | 22 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18785673 | ACP4 | acid phosphatase 4 | ENCODES a protein that exhibits acid phosphatase activity (inferred); hydrolase activity (inferred); phosphatase activity (inferred); INVOLVED IN peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); am elogenesis imperfecta type 1J (ortholog); FOUND IN glutamatergic synapse (ortholog); synaptic membrane (ortholog) | | | | Green Monkey | 25 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 16564961 | AC010325.2 | novel transcript, antisense to ACPT | | | | | Human | | name | gene, lncrna |