Accn3 Gene Search Result

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4 records found for search term Accn3

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
708578	Asic3	acid sensing ion channel subunit 3	ENCODES a protein that exhibits ligand-gated sodium channel activity; pH-gated calcium channel activity; pH-gated sodium channel activity; INVOLVED IN detection of chemical stimulus involved in sensory perception of pain; membrane depolarization; monoatomic ion transmembrane transport; ASSOCIATED WI ... (more) TH Inflammation (ortholog); FOUND IN perinuclear region of cytoplasm; plasma membrane; INTERACTS WITH acetylsalicylic acid; ammonium chloride; ATP	4	11652946	11657415	Rat	112	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1332245	Asic3	acid-sensing ion channel 3	Enables enterobactin transmembrane transporter activity and monoatomic cation channel activity. Acts upstream of or within several processes, including detection of stimulus involved in sensory perception of pain; response to acidic pH; and response to heat. Located in plasma membrane. Is expressed ... (more) in cranial ganglion; dorsal root ganglion; and pectoral girdle and thoracic body wall muscle. Orthologous to human ASIC3 (acid sensing ion channel subunit 3). [provided by Alliance of Genome Resources, Apr 2025]	5	24618449	24622836	Mouse	159	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1353665	ASIC3	acid sensing ion channel subunit 3	This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine ... (more) residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]	7	151048292	151052756	Human	106	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
12333147	ASIC3	acid sensing ion channel subunit 3	ENCODES a protein that exhibits ligand-gated sodium channel activity (ortholog); pH-gated calcium channel activity (ortholog); INVOLVED IN detection of chemical stimulus involved in sensory perception (ortholog); detection of chemical stimulus involved in sensory perception of pain (ortholog); detec ... (more) tion of mechanical stimulus involved in sensory perception (ortholog); ASSOCIATED WITH Inflammation (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)	16	15099023	15104088	Dog	58	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]