| 2948 | Aadat | aminoadipate aminotransferase | ENCODES a protein that exhibits 2-aminoadipate transaminase activity; kynurenine-glyoxylate transaminase activity; kynurenine-oxoglutarate transaminase activity; INVOLVED IN 2-oxoglutarate metabolic process (ortholog); glutamate metabolic process (ortholog); kynurenine metabolic process (ortholog); PARTICIPATES IN tryptophan metabolic pathway; 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aciduria type I pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol; mitochondrial matrix; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 16 | 34520236 | 34566388 | Rat | 174 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 735758 | Aadat | aminoadipate aminotransferase | Predicted to enable protein homodimerization activity and transaminase activity. Predicted to be involved in 2-oxoglutarate metabolic process; glutamate metabolic process; and kynurenine metabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; bra in; heart; liver; and metanephros. Orthologous to human AADAT (aminoadipate aminotransferase). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 60958877 | 60998711 | Mouse | 185 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1606004 | AADAT | aminoadipate aminotransferase | This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L- lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] | 4 | 170060222 | 170094292 | Human | 162 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 11989261 | AADAT | aminoadipate aminotransferase | ENCODES a protein that exhibits kynurenine-oxoglutarate transaminase activity (ortholog); INVOLVED IN 2-oxoglutarate metabolic process (inferred); alpha-amino acid metabolic process (inferred); glutamate metabolic process (inferred); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutar ic aciduria type I pathway; hyperlysinemia pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog) | 4 | 162283569 | 162313720 | Bonobo | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12144529 | AADAT | aminoadipate aminotransferase | ENCODES a protein that exhibits kynurenine-oxoglutarate transaminase activity (ortholog); INVOLVED IN 2-oxoglutarate metabolic process (inferred); glutamate metabolic process (inferred); kynurenine metabolic process (inferred); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aci duria type I pathway; hyperlysinemia pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH bisphenol A | 25 | 20920118 | 20944251 | Dog | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12674541 | Aadat | aminoadipate aminotransferase | ENCODES a protein that exhibits kynurenine-oxoglutarate transaminase activity (ortholog); INVOLVED IN 2-oxoglutarate metabolic process (inferred); alpha-amino acid metabolic process (inferred); glutamate metabolic process (inferred); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutar ic aciduria type I pathway; hyperlysinemia pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog) | NW_004936516 | 2030032 | 2052025 | Squirrel | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626115361 | Aadat | aminoadipate aminotransferase | ENCODES a protein that exhibits 2-aminoadipate transaminase activity (ortholog); glycine:2-oxoglutarate aminotransferase activity (ortholog); kynurenine-glyoxylate transaminase activity (ortholog); INVOLVED IN 2-oxoglutarate metabolic process (ortholog); glutamate metabolic process (ortholog); kynur enine metabolic process (ortholog); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aciduria type I pathway; hyperlysinemia pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog) | | | | Black Rat | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18424658 | AADAT | aminoadipate aminotransferase | ENCODES a protein that exhibits kynurenine-oxoglutarate transaminase activity (ortholog); INVOLVED IN 2-oxoglutarate metabolic process (inferred); alpha-amino acid metabolic process (inferred); glutamate metabolic process (inferred); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutar ic aciduria type I pathway; hyperlysinemia pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog) | | | | Green Monkey | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18909337 | Aadat | aminoadipate aminotransferase | ENCODES a protein that exhibits glycine:2-oxoglutarate aminotransferase activity (ortholog); kynurenine-oxoglutarate transaminase activity (ortholog); methionine-glyoxylate transaminase activity (ortholog); INVOLVED IN 2-oxoglutarate metabolic process (ortholog); glutamate metabolic process (ortholo g); kynurenine metabolic process (ortholog); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aciduria type I pathway; hyperlysinemia pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog) | | | | Naked Mole-Rat | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13853465 | AADAT | aminoadipate aminotransferase | ENCODES a protein that exhibits kynurenine-oxoglutarate transaminase activity (ortholog); INVOLVED IN 2-oxoglutarate metabolic process (inferred); glutamate metabolic process (inferred); kynurenine metabolic process (inferred); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aci duria type I pathway; hyperlysinemia pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog) | | | | Pig | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155253013 | aadat | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155233650 | aadat.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155247519 | aadat.S | | | | | | African Clawed Frog | | symbol | gene, null |