RGD:94625860 Rat Genome Database

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Variant: RGD:94625860 -  Canis lupus familiaris

RGD ID: 94625860
Genic Status: GENIC
Type: SNV (SO:0001483) 
Associated Genes: PKD2L2  
Reference Nucleotide: G
Variant Nucleotide: A
Position
Assembly Chr Position
CanFam3.1 11 25,618,524
JBrowse: View Region in Genome Browser (JBrowse)
Model
Breeds: Kunming Dog




Gene Symbol:PKD2L2
Accession:XM_005626598
Location:EXON
Amino Acid Prediction: G to D (nonsynonymous)
Amino Acid Position: 504
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
possibly damaging alignment     -1.379 -3.563 +2.184 273   XP_005626655   +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MAEASRWHRGGTPKPKLHYRKEVEIRTTLQELALYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGDERTNFKS
IRSITDFWKFMEGPLLEGLYWDSWYTNKTLYDLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMNECYDKYTS
KSEDMDEFGLKQETEWKYAAPTSSSPWHWGFVGVYQNGGFIFTLSKSKSETKNKFVDLKLNSWITRGTRVIFIDFSLYNA
NVNLFCIIRLAAEFPATGGIITSWQFYSVKLLRYVSYYDYIIASCEITFCIFLIVFTTQEAQKIREFKSAYFKSVWNWLE
LLLLVLCFVTVTFNIYCNVQIFLLLGDLLKNTEKYSDFYFLAYWHTYYNNVIAITIFFAWIKIFKFISFNKTMSQLSSTL
SRCLKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNAIFAQFRIVLGDFNFAGIQQANRILGPIYFITFIFFVFF
VLLNMFLAIINDTYSEVKADYSIDRRPDFELGKMIKKSYNNALEKLRLKKPEQDEDISMKGDLAEQARREGFDENEIQSA
EQMKKWKDRLEKKYYSTEIQDDYQPVTQQEFRELFLYAVELEKELHYVSLKLNRVMRKLSALQS*

Gene Symbol:PKD2L2
Accession:XM_022425338
Location:EXON
Amino Acid Prediction: G to D (nonsynonymous)
Amino Acid Position: 528
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -1.176 -3.280 +2.104 183   XP_022281046   +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MAEASRWHRGGTPKPKLHYRKEVEIRTTLQELALYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGDERTNFKS
IRSITDFWKFMEGPLLEGLYWDSWYTNKTLYDLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMNECYDKYTS
KSEDMDEFGLKQETEYRKFLEYISVRLSRLSIILFIPNRWKYAAPTSSSPWHWGFVGVYQNGGFIFTLSKSKSETKNKFV
DLKLNSWITRGTRVIFIDFSLYNANVNLFCIIRLAAEFPATGGIITSWQFYSVKLLRYVSYYDYIIASCEITFCIFLIVF
TTQEAQKIREFKSAYFKSVWNWLELLLLVLCFVTVTFNIYCNVQIFLLLGDLLKNTEKYSDFYFLAYWHTYYNNVIAITI
FFAWIKIFKFISFNKTMSQLSSTLSRCLKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNAIFAQFRIVLGDFNF
AGIQQANRILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIDRRPDFELGKMIKKSYNNALEKLRLKKPEQDED
ISMKGDLAEQARREGFDENEIQSAEQMKKWKDRLEKKYYSTEIQDDYQPVTQQEFRESCVTSELENFANIRPVRKCHFGN
QTEMCSTVGLEISVDFGFLRKHRT*

Gene Symbol:PKD2L2
Accession:XM_022425339
Location:EXON
Amino Acid Prediction: G to D (nonsynonymous)
Amino Acid Position: 528
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
possibly damaging alignment     -1.379 -3.563 +2.184 273   XP_022281047   +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MAEASRWHRGGTPKPKLHYRKEVEIRTTLQELALYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGDERTNFKS
IRSITDFWKFMEGPLLEGLYWDSWYTNKTLYDLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMNECYDKYTS
KSEDMDEFGLKQETEYRKFLEYISVRLSRLSIILFIPNRWKYAAPTSSSPWHWGFVGVYQNGGFIFTLSKSKSETKNKFV
DLKLNSWITRGTRVIFIDFSLYNANVNLFCIIRLAAEFPATGGIITSWQFYSVKLLRYVSYYDYIIASCEITFCIFLIVF
TTQEAQKIREFKSAYFKSVWNWLELLLLVLCFVTVTFNIYCNVQIFLLLGDLLKNTEKYSDFYFLAYWHTYYNNVIAITI
FFAWIKIFKFISFNKTMSQLSSTLSRCLKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNAIFAQFRIVLGDFNF
AGIQQANRILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIDRRPDFELGKMIKKSYNNALEKLRLKKPEQDED
ISMKGDLAEQARREGFDENEIQSAEQMKKWKDRLEKKYYSTEIQDDYQPVTQQEFRELFLYAVELEKELHYVSLKLNRVM
RKLSALQS*

Gene Symbol:PKD2L2
Accession:XM_022425340
Location:EXON
Amino Acid Prediction: G to D (nonsynonymous)
Amino Acid Position: 528
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -1.264 -3.486 +2.222 272   XP_022281048   +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MAEASRWHRGGTPKPKLHYRKEVEIRTTLQELALYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGDERTNFKS
IRSITDFWKFMEGPLLEGLYWDSWYTNKTLYDLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMNECYDKYTS
KSEDMDEFGLKQETEYRKFLEYISVRLSRLSIILFIPNRWKYAAPTSSSPWHWGFVGVYQNGGFIFTLSKSKSETKNKFV
DLKLNSWITRGTRVIFIDFSLYNANVNLFCIIRLAAEFPATGGIITSWQFYSVKLLRYVSYYDYIIASCEITFCIFLIVF
TTQEAQKIREFKSAYFKSVWNWLELLLLVLCFVTVTFNIYCNVQIFLLLGDLLKNTEKYSDFYFLAYWHTYYNNVIAITI
FFAWIKIFKFISFNKTMSQLSSTLSRCLKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNAIFAQFRIVLGDFNF
AGIQQANRILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIDRRPDFELGKMIKKSYNNALEKLRLKKPEQDED
ISMKGDLAEQARREGFDENEIQSAEQMKKWKDRLEKKYYSTEIQDDYQPVTQQEFREFPQSYQQTAWPFLVLPILRAAAS
QET*

Gene Symbol:PKD2L2
Accession:XM_022425341
Location:EXON
Amino Acid Prediction: G to D (nonsynonymous)
Amino Acid Position: 504
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -1.264 -3.486 +2.222 265   XP_022281049   +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MAEASRWHRGGTPKPKLHYRKEVEIRTTLQELALYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGDERTNFKS
IRSITDFWKFMEGPLLEGLYWDSWYTNKTLYDLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMNECYDKYTS
KSEDMDEFGLKQETEWKYAAPTSSSPWHWGFVGVYQNGGFIFTLSKSKSETKNKFVDLKLNSWITRGTRVIFIDFSLYNA
NVNLFCIIRLAAEFPATGGIITSWQFYSVKLLRYVSYYDYIIASCEITFCIFLIVFTTQEAQKIREFKSAYFKSVWNWLE
LLLLVLCFVTVTFNIYCNVQIFLLLGDLLKNTEKYSDFYFLAYWHTYYNNVIAITIFFAWIKIFKFISFNKTMSQLSSTL
SRCLKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNAIFAQFRIVLGDFNFAGIQQANRILGPIYFITFIFFVFF
VLLNMFLAIINDTYSEVKADYSIDRRPDFELGKMIKKSYNNALEKLRLKKPEQDEDISMKGDLAEQARREGFDENEIQSA
EQMKKWKDRLEKKYYSTEIQDDYQPVTQQEFRESCVTSELENFANIRPVRKCHFGNQTEMCSTVGLEISVDFGFLRKHRT
*

Gene Symbol:PKD2L2
Accession:XM_022425342
Location:EXON
Amino Acid Prediction: G to D (nonsynonymous)
Amino Acid Position: 370
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -1.172 -3.026 +1.854 175   XP_022281050   +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MAEASRWHRGGTPKPKLHYRKEVEIRTTLQELALYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGDERTNFKS
IRSITDFWKFMEGPLLEGLYWDSWYTNKTLYDLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMNECYDKYTS
KSEDMDEFGLKQETEYRKFLEYISVRLSRLSIILFIPNRWKYAAPTSSSPWHWGFVGVYQNGGFIFTLSKSKSETKNKFV
DLKLNSWITRGTRVIFIDFSLYNANVNLFCIIRLAAEFPATGGIITSWQFYSVKLLRYVSYYDYIIASCEITFCIFLIVF
TTQEAQKIREFKSAYFKSVWNWLELLLLVNMFLAIINDTYSEVKADYSIDRRPDFELGKMIKKSYNNALEKLRLKKPEQD
EDISMKGDLAEQARREGFDENEIQSAEQMKKWKDRLEKKYYSTEIQDDYQPVTQQEFRESCVTSELENFANIRPVRKCHF
GNQTEMCSTVGLEISVDFGFLRKHRT*

Gene Symbol:PKD2L2
Accession:XR_002631392
Location:EXON;NON-CODING

Gene Symbol:PKD2L2
Accession:XR_002631391
Location:EXON;NON-CODING

Gene Symbol:PKD2L2
Accession:XR_002631390
Location:EXON;NON-CODING

Gene Symbol:PKD2L2
Accession:XR_002631393
Location:EXON;NON-CODING

Kunming Dog (KM6)