RGD:78628396 Rat Genome Database

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Variant: RGD:78628396 -  Canis lupus familiaris

RGD ID: 78628396
Genic Status: GENIC
Type: SNV (SO:0001483) 
Associated Genes: SLC7A3  
Reference Nucleotide: C
Variant Nucleotide: G
Position
Assembly Chr Position
CanFam3.1 X 55,287,326
JBrowse: View Region in Genome Browser (JBrowse)
Model
Breeds: Chinese indigenous dogs, Tibetan Mastiff




Gene Symbol:SLC7A3
Accession:XM_005641454
Location:EXON
Amino Acid Prediction: G to A (nonsynonymous)
Amino Acid Position: 47
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -0.809 -2.670 +1.861 121   XP_005641511   -
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MLWQALRRFGQKLVRRRALEPGMAETRLARCLSTLDLVALGVGSTLAAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLA
GLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISQTLQGSISLHVPHVL
AEYPDFFAMGLVLLLTGLLALGASESALVTKVFTVVNLLVLGFVIISGFIKGDLHNWKLTEGDYKLTVAGLNDTYSLGPL
GSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQHSIPVGIVVSLFVCFLAYFGVSSALTLMMPYYQLQPESP
LPEAFLYTGWAPARYVVALGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARVHTGTHTPIVATVVSGIIAAFMAFL
FELTDLVDLMSIGTLLAYSLVAICVLILRYQPELKNEEDEVELQEENMAGAEKLTLQGLFCPLSSIPTPLSGQVVYVCSS
LVALLLTLLCLVLAQWPIPLVSGDPVWTVVVVLLLMLVTGITGVIWRQPQSSTPLHFKVPALPLLPLMSIFVNVYLMMQM
TAGTWARFGVWMLIGFAIYFGYGIQHSLEEVKSDQAPLKCRAKTVDLDLSNACTHSI*

Gene Symbol:SLC7A3
Accession:XM_005641455
Location:EXON
Amino Acid Prediction: G to A (nonsynonymous)
Amino Acid Position: 47
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -1.008 -2.534 +1.526 3   XP_005641512   -
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MLWQALRRFGQKLVRRRALEPGMAETRLARCLSTLDLVALGVGSTLAAGTASVARAWSSAFDNLIGNHISQTLQGSISLH
VPHVLAEYPDFFAMGLVLLLTGLLALGASESALVTKVFTVVNLLVLGFVIISGFIKGDLHNWKLTEGDYKLTVAGLNDTY
SLGPLGSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQHSIPVGIVVSLFVCFLAYFGVSSALTLMMPYYQL
QPESPLPEAFLYTGWAPARYVVALGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARVHTGTHTPIVATVVSGIIAA
FMAFLFELTDLVDLMSIGTLLAYSLVAICVLILRYQPELKNEEDEVELQEENMAGAEKLTLQGLFCPLSSIPTPLSGQVV
YVCSSLVALLLTLLCLVLAQWPIPLVSGDPVWTVVVVLLLMLVTGITGVIWRQPQSSTPLHFKVPALPLLPLMSIFVNVY
LMMQMTAGTWARFGVWMLIGFAIYFGYGIQHSLEEVKSDQAPLKCRAKTVDLDLSNACTHSI*

Gene Symbol:SLC7A3
Accession:XM_549065
Location:EXON
Amino Acid Prediction: G to A (nonsynonymous)
Amino Acid Position: 47
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment     -0.809 -2.670 +1.861 121   XP_549065   -
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MLWQALRRFGQKLVRRRALEPGMAETRLARCLSTLDLVALGVGSTLAAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLA
GLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISQTLQGSISLHVPHVL
AEYPDFFAMGLVLLLTGLLALGASESALVTKVFTVVNLLVLGFVIISGFIKGDLHNWKLTEGDYKLTVAGLNDTYSLGPL
GSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQHSIPVGIVVSLFVCFLAYFGVSSALTLMMPYYQLQPESP
LPEAFLYTGWAPARYVVALGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARVHTGTHTPIVATVVSGIIAAFMAFL
FELTDLVDLMSIGTLLAYSLVAICVLILRYQPELKNEEDEVELQEENMAGAEKLTLQGLFCPLSSIPTPLSGQVVYVCSS
LVALLLTLLCLVLAQWPIPLVSGDPVWTVVVVLLLMLVTGITGVIWRQPQSSTPLHFKVPALPLLPLMSIFVNVYLMMQM
TAGTWARFGVWMLIGFAIYFGYGIQHSLEEVKSDQAPLKCRAKTVDLDLSNACTHSI*
Chinese indigenous dogs (LJ2) Chinese indigenous dogs (LJ6) Chinese indigenous dogs (LJ9) Tibetan Mastiff (TM10)