RGD:58204921 Rat Genome Database

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Variant: RGD:58204921 -  Rattus norvegicus

RGD ID: 58204921
Genic Status: GENIC
Type: SNV (SO:0001483) 
Associated Genes: Casp8ap2  
Reference Nucleotide: A
Variant Nucleotide: G
Position
Assembly Chr Position
Rnor_5.0 5 52,475,857
JBrowse: View Region in Genome Browser (JBrowse)
Model




Gene Symbol:Casp8ap2
Accession:NM_001107921
Location:EXON
Amino Acid Prediction: K to R (nonsynonymous)
Amino Acid Position: 732
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment   NO -1.381 -3.277 +1.896 143   NP_001101391   +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MAADDDNGDGTGLFDVCPASPLKNNDEGSLDIYAGLDSTVSDSTARSCVSFRNCLDLYEEILTEEGTAKEATYSDLQIEY
GKCQQQMKDLMKRFKEIQTQNLNLKNENQSLKKNISALIKTARVEINRKDEEINHLHQRLSEFPHFRNNHKTARTKDSRS
KSPHLDNCSKTDHGVKSDVQKDIHPNTSQPNLEKEGKSHSEAQNSLHLSTGIEKHCTNNVWSRSPYQVSEGNSNEDNRRG
RNGVRHSQGSRGTDRTQKDLNSSCNDGEPRDKEAASRLHGNPEKHGSSEARAENKISEIKSSTGLGNKSERSASSWEKET
SRERPHTRVEPQNDKNLERQNERLQNTHRKELQSQDKAERKGDVKFKPAGEEQGHRGRVDRALPPHSKNDMKYYGFNKYH
PEERRGREDGKRDRGMSSHGFQDRRCSSSLSSNRNSKYPHSKEVSVAHQWENTPFKAERHRTEDRRKRERENKEESRHVK
SDKKSPPEHLQRTHKDTKKSTANGKRQTEQKHGKGPVSTSELSKGTDNRECTMKVENGPNEAKGKDLKLSFMEKLNLTLS
PAKKQPVCQDNEHQIIGVPKPSGVCDSQSLEKTETVACLPSVSEQDREEPKSELPEPKEALSATSQPRTSIPENKVKEEN
RLLFKSVENTVPCELLACGTEISFPAPVEIEQARCLVQSMEVEETCAGARAAASVVMRVLPEHASEDFSQELGTKRHDDI
NSCDISEGGKKRVVLSPKAAAASESHLEPVVEEPSISPVNCSGDNNPKLEPSLEERPKVENKSSPLEPCLPKEMFVPSPQ
KTELIDHKIDTGESNSVYQDDDNSVLSIDFNNLRPIPEPISPLNSPVRPVSKVLSMESSCTIPLYDSSHKDEFPSNSTLS
TFKSQSDLNKENEKPVPKLDKCSEAESCKNLSVDELEEGEIRSDDEESVAQKRLEKSARPRTSTEVPPGKISPGSRRSTV
HVHKDNGRTVVKLPRDRITWSQRSNESRPSNTERKSKTMSISSLEKILPLILAPSSVWEVMHMLRLLGKHVRKNYMKFKI
KFSLTQFHRIIESAILSFTSLIRYLDLSKICKSVSTLQKSLCDVIESNLKQVKKNGIVDRLFEQQQTDMKKKLWKFVDEQ
LDYLFEKLKKILLKFCDSVKHENDSSEGKLGKKYKERAQHSNCQKKKMDNKEIRREKVLKSENTVNFKSSLGCEKFEEKH
QDQNKTNTTTVKHDVKRTFSTCTDNNTKNSECKEQFLGMNCPSTPRPGETEGNVEEGTPAAQHACVKSERGFEILTEQQA
SSLTFNLVSDAQMGEIFKSLLQGSDLLDTGGTEKAEWELKTPEKQLLESLKCESAPACTTEELVSEAASLCPKVISDDNW
SLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSSNLALSKDNVYSSEKSKPCISSILLEDLAVSLTVPSPLKSDGHLSFL
KPEVLSTSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSWTSRSVASGFQYHPNLPMHAVIMEKSNDH
FIVKIRRATPSTSPGLKHGMVAEESLTPLPRTGKEADGAAEKEPTLFQSTVLNPVQDLENSDKSIDKSKPTHEDQNSIVQ
TQVPDIYEFLKDASNKVVHCDQVVDDCFKLHQVWEPKVSESLQELPSMEKNAHSVDDHLPNTHIDLTKDPATETKSLELM
DVTVLDIDHLEHSKPNLDQDAQITCTSLQHDAVDAFIDLTHDVSNESKNESNEPVLTVEGVGCQVICIDDDNHKEGKVGK
VNSSLECTVEETCIDLTSESAGSFEVKRHTLKSEPPSKSDCLELPETLGNGHKKRKNSPAVSHSSQKKQRKDMDLSSEKT
KRLSPNSDRTGDAHRKHGSKKREPAVSDTSLSSEVNPEVKGSTAPLATFPGSLSAKNVIKKKGEIIVSWTRNDDREILLE
CQKRMPSLKTFTHLAVKLNKNPNQVSERFQQLKKLFEKSKCR*

Gene Symbol:Casp8ap2
Accession:XM_006237973
Location:EXON
Amino Acid Prediction: K to R (nonsynonymous)
Amino Acid Position: 732
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment   NO -1.381 -3.277 +1.896 143   XP_006238035   +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MAADDDNGDGTGLFDVCPASPLKNNDEGSLDIYAGLDSTVSDSTARSCVSFRNCLDLYEEILTEEGTAKEATYSDLQIEY
GKCQQQMKDLMKRFKEIQTQNLNLKNENQSLKKNISALIKTARVEINRKDEEINHLHQRLSEFPHFRNNHKTARTKDSRS
KSPHLDNCSKTDHGVKSDVQKDIHPNTSQPNLEKEGKSHSEAQNSLHLSTGIEKHCTNNVWSRSPYQVSEGNSNEDNRRG
RNGVRHSQGSRGTDRTQKDLNSSCNDGEPRDKEAASRLHGNPEKHGSSEARAENKISEIKSSTGLGNKSERSASSWEKET
SRERPHTRVEPQNDKNLERQNERLQNTHRKELQSQDKAERKGDVKFKPAGEEQGHRGRVDRALPPHSKNDMKYYGFNKYH
PEERRGREDGKRDRGMSSHGFQDRRCSSSLSSNRNSKYPHSKEVSVAHQWENTPFKAERHRTEDRRKRERENKEESRHVK
SDKKSPPEHLQRTHKDTKKSTANGKRQTEQKHGKGPVSTSELSKGTDNRECTMKVENGPNEAKGKDLKLSFMEKLNLTLS
PAKKQPVCQDNEHQIIGVPKPSGVCDSQSLEKTETVACLPSVSEQDREEPKSELPEPKEALSATSQPRTSIPENKVKEEN
RLLFKSVENTVPCELLACGTEISFPAPVEIEQARCLVQSMEVEETCAGARAAASVVMRVLPEHASEDFSQELGTKRHDDI
NSCDISEGGKKRVVLSPKAAAASESHLEPVVEEPSISPVNCSGDNNPKLEPSLEERPKVENKSSPLEPCLPKEMFVPSPQ
KTELIDHKIDTGESNSVYQDDDNSVLSIDFNNLRPIPEPISPLNSPVRPVSKVLSMESSCTIPLYDSSHKDEFPSNSTLS
TFKSQSDLNKENEKPVPKLDKCSEAESCKNLSVDELEEGEIRSDDEESVAQKRLEKSARPRTSTEVPPGKISPGSRRSTV
HVHKDNGRTVVKLPRDRITWSQRSNESRPSNTERKSKTMSISSLEKILPLILAPSSVWEVMHMLRLLGKHVRKNYMKFKI
KFSLTQFHRIIESAILSFTSLIRYLDLSKICKSVSTLQKSLCDVIESNLKQVKKNGIVDRLFEQQQTDMKKKLWKFVDEQ
LDYLFEKLKKILLKFCDSVKHENDSSEGKLGKKYKERAQHSNCQKKKMDNKEIRREKVLKSENTVNFKSSLGCEKFEEKH
QDQNKTNTTTVKHDVKRTFSTCTDNNTKNSECKEQFLGMNCPSTPRPGETEGNVEEGTPAAQHACVKSERGFEILTEQQA
SSLTFNLVSDAQMGEIFKSLLQGSDLLDTGGTEKAEWELKTPEKQLLESLKCESAPACTTEELVSEAASLCPKVISDDNW
SLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSSNLALSKDNVYSSEKSKPCISSILLEDLAVSLTVPSPLKSDGHLSFL
KPEVLSTSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSWTSRSVASGFQYHPNLPMHAVIMEKSNDH
FIVKIRRATPSTSPGLKHGMVAEESLTPLPRTGKEADGAAEKEPTLFQSTVLNPVQDLENSDKSIDKSKPTHEDQNSIVQ
TQVPDIYEFLKDASNKVVHCDQVVDDCFKLHQVWEPKVSESLQELPSMEKNAHSVDDHLPNTHIDLTKDPATETKSLELM
DVTVLDIDHLEHSKPNLDQDAQITCTSLQHDAVDAFIDLTHDVSNESKNESNEPVLTVEGVGCQVICIDDDNHKEGKVGK
VNSSLECTVEETCIDLTSESAGSFEVKRHTLKSEPPSKSDCLELPETLGNGHKKRKNSPAVSHSSQKKQRKDMDLSSEKT
KRLSPNSDRTGDAHRKHGSKKREPAVSDTSLSSEVNPEVKGSTAPLATFPGSLSAKNVIKKKGEIIVSWTRNDDREILLE
CQKRMPSLKTFTHLAVKLNKNPNQVSERFQQLKKLFEKSKCR*

Gene Symbol:Casp8ap2
Accession:XM_006237974
Location:EXON
Amino Acid Prediction: K to R (nonsynonymous)
Amino Acid Position: 732
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment   NO -1.381 -3.277 +1.896 143   XP_006238036   +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MAADDDNGDGTGLFDVCPASPLKNNDEGSLDIYAGLDSTVSDSTARSCVSFRNCLDLYEEILTEEGTAKEATYSDLQIEY
GKCQQQMKDLMKRFKEIQTQNLNLKNENQSLKKNISALIKTARVEINRKDEEINHLHQRLSEFPHFRNNHKTARTKDSRS
KSPHLDNCSKTDHGVKSDVQKDIHPNTSQPNLEKEGKSHSEAQNSLHLSTGIEKHCTNNVWSRSPYQVSEGNSNEDNRRG
RNGVRHSQGSRGTDRTQKDLNSSCNDGEPRDKEAASRLHGNPEKHGSSEARAENKISEIKSSTGLGNKSERSASSWEKET
SRERPHTRVEPQNDKNLERQNERLQNTHRKELQSQDKAERKGDVKFKPAGEEQGHRGRVDRALPPHSKNDMKYYGFNKYH
PEERRGREDGKRDRGMSSHGFQDRRCSSSLSSNRNSKYPHSKEVSVAHQWENTPFKAERHRTEDRRKRERENKEESRHVK
SDKKSPPEHLQRTHKDTKKSTANGKRQTEQKHGKGPVSTSELSKGTDNRECTMKVENGPNEAKGKDLKLSFMEKLNLTLS
PAKKQPVCQDNEHQIIGVPKPSGVCDSQSLEKTETVACLPSVSEQDREEPKSELPEPKEALSATSQPRTSIPENKVKEEN
RLLFKSVENTVPCELLACGTEISFPAPVEIEQARCLVQSMEVEETCAGARAAASVVMRVLPEHASEDFSQELGTKRHDDI
NSCDISEGGKKRVVLSPKAAAASESHLEPVVEEPSISPVNCSGDNNPKLEPSLEERPKVENKSSPLEPCLPKEMFVPSPQ
KTELIDHKIDTGESNSVYQDDDNSVLSIDFNNLRPIPEPISPLNSPVRPVSKVLSMESSCTIPLYDSSHKDEFPSNSTLS
TFKSQSDLNKENEKPVPKLDKCSEAESCKNLSVDELEEGEIRSDDEESVAQKRLEKSARPRTSTEVPPGKISPGSRRSTV
HVHKDNGRTVVKLPRDRITWSQRSNESRPSNTERKSKTMSISSLEKILPLILAPSSVWEVMHMLRLLGKHVRKNYMKFKI
KFSLTQFHRIIESAILSFTSLIRYLDLSKICKSVSTLQKSLCDVIESNLKQVKKNGIVDRLFEQQQTDMKKKLWKFVDEQ
LDYLFEKLKKILLKFCDSVKHENDSSEGKLGKKYKERAQHSNCQKKKMDNKEIRREKVLKSENTVNFKSSLGCEKFEEKH
QDQNKTNTTTVKHDVKRTFSTCTDNNTKNSECKEQFLGMNCPSTPRPGETEGNVEEGTPAAQHACVKSERGFEILTEQQA
SSLTFNLVSDAQMGEIFKSLLQGSDLLDTGGTEKAEWELKTPEKQLLESLKCESAPACTTEELVSEAASLCPKVISDDNW
SLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSSNLALSKDNVYSSEKSKPCISSILLEDLAVSLTVPSPLKSDGHLSFL
KPEVLSTSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSWTSRSVASGFQYHPNLPMHAVIMEKSNDH
FIVKIRRATPSTSPGLKHGMVAEESLTPLPRTGKEADGAAEKEPTLFQSTVLNPVQDLENSDKSIDKSKPTHEDQNSIVQ
TQVPDIYEFLKDASNKVVHCDQVVDDCFKLHQVWEPKVSESLQELPSMEKNAHSVDDHLPNTHIDLTKDPATETKSLELM
DVTVLDIDHLEHSKPNLDQDAQITCTSLQHDAVDAFIDLTHDVSNESKNESNEPVLTVEGVGCQVICIDDDNHKEGKVGK
VNSSLECTVEETCIDLTSESAGSFEVKRHTLKSEPPSKSDCLELPETLGNGHKKRKNSPAVSHSSQKKQRKDMDLSSEKT
KRLSPNSDRTGDAHRKHGSKKREPAVSDTSLSSEVNPEVKGSTAPLATFPGSLSAKNVIKKKGEIIVSWTRNDDREILLE
CQKRMPSLKTFTHLAVKLNKNPNQVSERFQQLKKLFEKSKCR*

Gene Symbol:Casp8ap2
Accession:XM_006237975
Location:EXON
Amino Acid Prediction: K to R (nonsynonymous)
Amino Acid Position: 732
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
probably damaging alignment   NO -1.381 -3.277 +1.896 143   XP_006238037   +
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MAADDDNGDGTGLFDVCPASPLKNNDEGSLDIYAGLDSTVSDSTARSCVSFRNCLDLYEEILTEEGTAKEATYSDLQIEY
GKCQQQMKDLMKRFKEIQTQNLNLKNENQSLKKNISALIKTARVEINRKDEEINHLHQRLSEFPHFRNNHKTARTKDSRS
KSPHLDNCSKTDHGVKSDVQKDIHPNTSQPNLEKEGKSHSEAQNSLHLSTGIEKHCTNNVWSRSPYQVSEGNSNEDNRRG
RNGVRHSQGSRGTDRTQKDLNSSCNDGEPRDKEAASRLHGNPEKHGSSEARAENKISEIKSSTGLGNKSERSASSWEKET
SRERPHTRVEPQNDKNLERQNERLQNTHRKELQSQDKAERKGDVKFKPAGEEQGHRGRVDRALPPHSKNDMKYYGFNKYH
PEERRGREDGKRDRGMSSHGFQDRRCSSSLSSNRNSKYPHSKEVSVAHQWENTPFKAERHRTEDRRKRERENKEESRHVK
SDKKSPPEHLQRTHKDTKKSTANGKRQTEQKHGKGPVSTSELSKGTDNRECTMKVENGPNEAKGKDLKLSFMEKLNLTLS
PAKKQPVCQDNEHQIIGVPKPSGVCDSQSLEKTETVACLPSVSEQDREEPKSELPEPKEALSATSQPRTSIPENKVKEEN
RLLFKSVENTVPCELLACGTEISFPAPVEIEQARCLVQSMEVEETCAGARAAASVVMRVLPEHASEDFSQELGTKRHDDI
NSCDISEGGKKRVVLSPKAAAASESHLEPVVEEPSISPVNCSGDNNPKLEPSLEERPKVENKSSPLEPCLPKEMFVPSPQ
KTELIDHKIDTGESNSVYQDDDNSVLSIDFNNLRPIPEPISPLNSPVRPVSKVLSMESSCTIPLYDSSHKDEFPSNSTLS
TFKSQSDLNKENEKPVPKLDKCSEAESCKNLSVDELEEGEIRSDDEESVAQKRLEKSARPRTSTEVPPGKISPGSRRSTV
HVHKDNGRTVVKLPRDRITWSQRSNESRPSNTERKSKTMSISSLEKILPLILAPSSVWEVMHMLRLLGKHVRKNYMKFKI
KFSLTQFHRIIESAILSFTSLIRYLDLSKICKSVSTLQKSLCDVIESNLKQVKKNGIVDRLFEQQQTDMKKKLWKFVDEQ
LDYLFEKLKKILLKFCDSVKHENDSSEGKLGKKYKERAQHSNCQKKKMDNKEIRREKVLKSENTVNFKSSLGCEKFEEKH
QDQNKTNTTTVKHDVKRTFSTCTDNNTKNSECKEQFLGMNCPSTPRPGETEGNVEEGTPAAQHACVKSERGFEILTEQQA
SSLTFNLVSDAQMGEIFKSLLQGSDLLDTGGTEKAEWELKTPEKQLLESLKCESAPACTTEELVSEAASLCPKVISDDNW
SLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSSNLALSKDNVYSSEKSKPCISSILLEDLAVSLTVPSPLKSDGHLSFL
KPEVLSTSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSWTSRSVASGFQYHPNLPMHAVIMEKSNDH
FIVKIRRATPSTSPGLKHGMVAEESLTPLPRTGKEADGAAEKEPTLFQSTVLNPVQDLENSDKSIDKSKPTHEDQNSIVQ
TQVPDIYEFLKDASNKVVHCDQVVDDCFKLHQVWEPKVSESLQELPSMEKNAHSVDDHLPNTHIDLTKDPATETKSLELM
DVTVLDIDHLEHSKPNLDQDAQITCTSLQHDAVDAFIDLTHDVSNESKNESNEPVLTVEGVGCQVICIDDDNHKEGKVGK
VNSSLECTVEETCIDLTSESAGSFEVKRHTLKSEPPSKSDCLELPETLGNGHKKRKNSPAVSHSSQKKQRKDMDLSSEKT
KRLSPNSDRTGDAHRKHGSKKREPAVSDTSLSSEVNPEVKGSTAPLATFPGSLSAKNVIKKKGEIIVSWTRNDDREILLE
CQKRMPSLKTFTHLAVKLNKNPNQVSERFQQLKKLFEKSKCR*
IS/Kyo (KyushuU) IS-Tlk/Kyo (KyushuU)