Strain Report - Rat Genome Database

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Strain: (F344.OLETF-(D14Rat23-D14Rat12)(D14Rat8-D14Rat26)/2Tj x F344.Cg-Leprfa(D7Mgh16-D7Mgh20))F1

Symbol: (F344.OLETF-(D14Rat23-D14Rat12)(D14Rat8-D14Rat26)/2Tj x F344.Cg-Leprfa(D7Mgh16-D7Mgh20))F1
Strain: (F344.OLETF-(D14Rat23-D14Rat12)(D14Rat8-D14Rat26)/2 x F344.Cg-Leprfa(D7Mgh16-D7Mgh20))F1
Substrain: Tj
RGD ID: 2305988
Citation ID: RRID:RGD_2305988
Ontology ID: RS:0001731
Also Known As: (F344.OLETF-(D14Rat23-D14Rat12)(D14Rat8-D14Rat26)/2Tj x F344.Cg-Leprfa(D7Mgh16-D7Mgh20))F1; (F.O-Nidd2OF Nidd10OF/2Tj x F.Cg-leprZFNidd1OF)F1; F.O-Nidd2-10/ofNSxF.ZF/O-lepr; Nidd1/of;NBRP Rat No: 0417; (F344.OLETF-(D14Rat23-D14Rat12)(D14Rat8-D14Rat26)/2Tj x F344.Cg-Leprfa(D7Mgh16-D7Mgh20))F1; (F344.OLETF-(D14Rat23-D14Rat12)(D14Rat8-D14Rat26)/2Tj x F344.Cg-Lepr^[fa](D7Mgh16-D7Mgh20))F1
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: Developed by the DEPOSITOR
Coat Color: Albino
Inbred Generations: F1
Last Known Status: Cryopreserved Embryo
Research Usage Diabetes Obesity


References - curated
# Reference Title Reference Citation
1. Single diabetic QTL derived from OLETF rat is a sufficient agent for severe diabetic phenotype in combination with leptin-signaling deficiency. Kose H, etal., Exp Diabetes Res. 2012;2012:858121. doi: 10.1155/2012/858121. Epub 2012 Dec 5.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_reproduction Poor breeding performance. 1302502