Strain Report - Rat Genome Database

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Strain: STOCK Aspaem34Kyo Hcn1A354V/Kyo

Symbol: STOCK Aspaem34Kyo Hcn1A354V/Kyo
Strain: STOCK Aspaem34Kyo Hcn1A354V
Substrain: Kyo
RGD ID: 13464320
Citation ID: RRID:RGD_13464320
Ontology ID: RS:0004572
Alleles: Hcn1A354V;   Aspaem34Kyo
Also known as: NBRP Rat No: 0870; STOCK Aspaem34Kyo Hcn1A354V/Kyo
Type: inbred
Source: National BioResource Project for the Rat in Japan
Origin: This double mutant strain was established by crossing WTC/Kyo (NBRP Rat No. 0020) and F344-Aspaem34Kyo (NBRP Rat No. 0806). WTC/Kyo has a missense mutation (Hcn1A354V) in Hcn1 (Hyperpolarization-activated cyclic nucleotide-gated channel 1) gene and F344-Aspaem34Kyo has a 16-bp deletion in the exon4 of Aspa (Aspartoacylase) gene (c.622_637del).
Coat Color: albino
Inbred Generations: F6
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View
Tremor  (IMP)


References

References - curated
1. Nishitani A, etal., Exp Anim. 2016 Jul 29;65(3):293-301. doi: 10.1538/expanim.16-0007. Epub 2016 Mar 30.

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-14 STOCK Aspaem34Kyo Hcn1A354V/Kyo    STOCK Aspaem34Kyo Hcn1A354V/Kyo    Symbol updated 68687 APPROVED
2018-03-14 STOCK Aspaem34Kyo Hcn1A354V/Kyo    STOCK Aspaem34Kyo Hcn1A354V/Kyo    Symbol updated 68687 APPROVED