GWAS809975_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS809975_H (hemoglobin measurement QTL GWAS809975 (human)) Homo sapiens

Symbol: GWAS809975_H
Name: hemoglobin measurement QTL GWAS809975 (human)
RGD ID: 407160999
Trait: hemoglobin measurement
Measurement Type: hemoglobin measurement   (CMO:0000508)    
LOD Score: Not Available
P Value: 1E-100
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38626,072,764 - 26,072,765RGD_MAPPER_PIPELINEGRCh38
GRCh37626,072,992 - 26,072,993RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS809975_HHumanhemoglobin measurement  IAGPrs144861591405850206Based on the EFO term IDGWAS_CATALOGPMID:37596262

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS809975_HHumanhemoglobin measurement  IAGPrs144861591405850206 GWAS_CATALOGPMID:37596262
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs144861591)
Human AssemblyChrPosition (strand)Source
GRCh38626,072,764 - 26,072,765RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407416649GWAS1065625_Hneuroimaging measurement QTL GWAS1065625 (human)1e-20neuroimaging measurement62607276426072765Human
407405129GWAS1054105_Hmean corpuscular volume QTL GWAS1054105 (human)3e-640mean corpuscular volumemean corpuscular volume (CMO:0000038)62607276426072765Human
407416650GWAS1065626_Hneuroimaging measurement QTL GWAS1065626 (human)2e-22neuroimaging measurement62607276426072765Human
407414284GWAS1063260_Hmean corpuscular volume QTL GWAS1063260 (human)6e-727mean corpuscular volumemean corpuscular volume (CMO:0000038)62607276426072765Human
407416654GWAS1065630_Hneuroimaging measurement QTL GWAS1065630 (human)2e-19brain volume measurementbrain morphological measurement (CMO:0000136)62607276426072765Human
407416655GWAS1065631_Hneuroimaging measurement QTL GWAS1065631 (human)1e-19neuroimaging measurement62607276426072765Human
407419663GWAS1068639_Hhemoglobin A1 measurement QTL GWAS1068639 (human)9e-185hemoglobin A1 measurement62607276426072765Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
407369480GWAS1018456_Hhemoglobin measurement QTL GWAS1018456 (human)1e-162hemoglobin measurementhemoglobin measurement (CMO:0000508)62607276426072765Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
407367122GWAS1016098_Hmean corpuscular volume QTL GWAS1016098 (human)1e-340mean corpuscular volumemean corpuscular volume (CMO:0000038)62607276426072765Human
407124189GWAS773165_Hphospholipids:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS773165 (human)1e-18phospholipids:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)62607276426072765Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
407121561GWAS770537_Hcholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS770537 (human)4e-16cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)62607276426072765Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human
407389655GWAS1038631_Hobsolete_red blood cell distribution width QTL GWAS1038631 (human)7e-216obsolete_red blood cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)62607276426072765Human
407417704GWAS1066680_Hglycoprotein measurement QTL GWAS1066680 (human)2e-08glycoprotein measurement62607276426072765Human
407127206GWAS776182_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS776182 (human)4e-11low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)62607276426072765Human
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
407160999GWAS809975_Hhemoglobin measurement QTL GWAS809975 (human)1e-100hemoglobin measurementhemoglobin measurement (CMO:0000508)62607276426072765Human
407367714GWAS1016690_Hhematocrit QTL GWAS1016690 (human)7e-65hematocrithematocrit (CMO:0000037)62607276426072765Human
406960935GWAS609911_Htransferrin receptor protein 1 measurement QTL GWAS609911 (human)2e-23transferrin receptor protein 1 measurement62607276426072765Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
407405408GWAS1054384_Hliver iron measurement QTL GWAS1054384 (human)4e-136liver iron measurementliver iron measurement (CMO:0003574)62607276426072765Human
407190828GWAS839804_Herythrocyte measurement QTL GWAS839804 (human)1e-82erythrocyte measurementred blood cell measurement (CMO:0001356)62607276426072765Human
407387425GWAS1036401_Hmean corpuscular hemoglobin QTL GWAS1036401 (human)1e-515mean corpuscular hemoglobinmean corpuscular hemoglobin (CMO:0000290)62607276426072765Human
407416994GWAS1065970_Hbrain volume measurement QTL GWAS1065970 (human)6e-16brain volume measurementbrain morphological measurement (CMO:0000136)62607276426072765Human
407122991GWAS771967_Hcholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS771967 (human)4e-15cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)62607276426072765Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
407123881GWAS772857_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS772857 (human)1e-09low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)62607276426072765Human
407169066GWAS818042_Herythrocyte measurement QTL GWAS818042 (human)1e-32erythrocyte measurementred blood cell measurement (CMO:0001356)62607276426072765Human
407027122GWAS676098_Hsex hormone-binding globulin measurement QTL GWAS676098 (human)2e-14sex hormone-binding globulin measurement62607276426072765Human
407408248GWAS1057224_Hsex hormone-binding globulin measurement QTL GWAS1057224 (human)5e-11sex hormone-binding globulin measurement62607276426072765Human
407084341GWAS733317_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS733317 (human)1e-10cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)62607276426072765Human
407414071GWAS1063047_Hmean corpuscular hemoglobin QTL GWAS1063047 (human)1e-1029mean corpuscular hemoglobinmean corpuscular hemoglobin (CMO:0000290)62607276426072765Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
None Available GCST004621 Red cell distribution width 171,529 European ancestry individuals T 0.0771 7E-216 215.155 rs144861591 0.2083623 Red cell distribution width (EFO:0009188)
 PMID:27863252
GWAS609911_H GCST90249979 Transferrin receptor protein 1 levels 10,708 European ancestry individuals T 0.06 2E-23 22.699 rs144861591 0.278 transferrin receptor protein 1 measurement (EFO:0802142)
 PMID:34648354
GWAS676098_H GCST90239821 Sex hormone-binding globulin levels 163,363 British ancestry men ? NR 2E-14 13.699 rs144861591 0.0463214 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:36653534
GWAS733317_H GCST90302008 Total cholesterol to total lipids ratio in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.0654 1E-10 10 rs144861591 0.0578 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS770537_H GCST90302080 Total cholesterol to total lipids ratio in small HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.0654 4E-16 15.398 rs144861591 0.0724 cholesterol:total lipids ratio (EFO:0020943)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS771967_H GCST90302082 Cholesteryl esters to total lipids ratio in small HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.0654 4E-15 14.398 rs144861591 0.07 cholesteryl esters:total lipids ratio (EFO:0020944)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS772857_H GCST90302044 Total cholesterol to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.0653 1E-9 9 rs144861591 0.0543 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS773165_H GCST90302088 Phospholipids to total lipids ratio in small HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.0662 1E-18 18 rs144861591 0.0756 phospholipids:total lipids ratio (EFO:0020946)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS776182_H GCST90302100 Phospholipids to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.0661 4E-11 10.398 rs144861591 0.0565 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
None Available GCST90302052 Phospholipids to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.066 1E-9 9 rs144861591 0.0522 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS809975_H GCST90281207 Hyper-haemoglobinised percentage of red cells 38,553 European ancestry individuals T 0.0769 1E-100 100 rs144861591 0.284133 hemoglobin measurement (EFO:0004509)
 PMID:37596262
GWAS818042_H GCST90281203 Red blood cell side fluorescence 30,551 European ancestry individuals T 0.0779 1E-32 32 rs144861591 0.174774 erythrocyte measurement (EFO:0005047)
 PMID:37596262
GWAS839804_H GCST90281202 Red blood cell side scatter 30,528 European ancestry individuals T 0.078 1E-82 82 rs144861591 0.275814 erythrocyte measurement (EFO:0005047)
 PMID:37596262
GWAS1016098_H GCST004602 Mean corpuscular volume 172,433 European ancestry individuals T 0.077 1E-340 340 rs144861591 0.2611127 mean corpuscular volume (EFO:0004526)
 PMID:27863252
GWAS1016690_H GCST004604 Hematocrit 173,039 European ancestry individuals T 0.0771 7E-65 64.155 rs144861591 0.112755 hematocrit (EFO:0004348)
 PMID:27863252
GWAS1018456_H GCST004615 Hemoglobin concentration 172,925 European ancestry individuals T 0.0771 1E-162 162 rs144861591 0.1809882 hemoglobin measurement (EFO:0004509)
 PMID:27863252
GWAS1036401_H GCST004630 Mean corpuscular hemoglobin 172,332 European ancestry individuals T 0.077 1E-515 515 rs144861591 0.3222512 mean corpuscular hemoglobin (EFO:0004527)
 PMID:27863252
GWAS1054105_H GCST90056174 Mean corpuscular volume 362,595 British ancestry individuals C 0.924 3E-640 639.523 rs144861591 1.1 mean corpuscular volume (EFO:0004526)
 PMID:34104963
GWAS1054384_H GCST90016674 Liver iron content 32,858 European ancestry individuals ? NR 4E-136 135.398 rs144861591 0.372 liver iron measurement (EFO:0010056)
 PMID:34128465
GWAS1057224_H GCST90027091 Sex hormone-binding globulin levels 148,248 British ancestry men T 0.08 5E-11 10.302 rs144861591 0.99 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:34321204
GWAS1063047_H GCST90018964 Mean corpuscular hemoglobin 350,472 European ancestry individuals, 128,028 East Asian ancestry individuals T NR 1E-1029 1029 rs144861591 0.3043 mean corpuscular hemoglobin (EFO:0004527)
 PMID:34594039
GWAS1063260_H GCST90018966 Mean corpuscular volume 350,473 European ancestry individuals, 129,832 East Asian ancestry individuals T NR 6E-727 726.222 rs144861591 0.2566 mean corpuscular volume (EFO:0004526)
 PMID:34594039
GWAS1065625_H GCST90003767 aseg lh intensity Cerebellum-Cortex 21,282 British ancestry individuals T 0.076 1E-20 20 rs144861591 0.171 neuroimaging measurement (EFO:0004346)
 PMID:33875891
GWAS1065626_H GCST90003770 aseg lh intensity Putamen 21,282 British ancestry individuals T 0.076 2E-22 21.699 rs144861591 0.179 neuroimaging measurement (EFO:0004346)
 PMID:33875891
GWAS1065630_H GCST90003781 aseg rh intensity Cerebellum-Cortex 21,282 British ancestry individuals T 0.076 2E-19 18.699 rs144861591 0.166 neuroimaging measurement (EFO:0004346)
 PMID:33875891
GWAS1065631_H GCST90003784 aseg rh intensity Putamen 21,282 British ancestry individuals T 0.076 1E-19 19 rs144861591 0.167 neuroimaging measurement (EFO:0004346)
 PMID:33875891
None Available GCST90002551 IDP T1 FAST ROIs L putamen 22,133 British ancestry individuals T 0.076 2E-19 18.699 rs144861591 0.162 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1065970_H GCST90002552 IDP T1 FAST ROIs R putamen 22,133 British ancestry individuals T 0.076 6E-16 15.222 rs144861591 0.146 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066680_H GCST90092821 Glycoprotein acetyls levels 115,082 European ancestry individuals C 0.924475 2E-8 7.699 rs144861591 0.0437027 glycoprotein measurement (EFO:0004555)
 PMID:35213538
GWAS1068639_H GCST90018958 Hemoglobin A1c levels 344,182 European ancestry individuals, 71,221 East Asian ancestry individuals T NR 9E-185 184.046 rs144861591 0.1254 hemoglobin A1 measurement (EFO:0007629)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90281207 GWAS Catalog

RGD Curation Notes
Note Type Note Reference