Dpp7 (dipeptidylpeptidase 7) - Rat Genome Database

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Gene: Dpp7 (dipeptidylpeptidase 7) Rattus norvegicus
Analyze
Symbol: Dpp7
Name: dipeptidylpeptidase 7
RGD ID: 71073
Description: Enables dipeptidyl-peptidase activity. Involved in protein catabolic process. Predicted to be located in Golgi apparatus and lysosome. Predicted to be active in vesicle. Orthologous to human DPP7 (dipeptidyl peptidase 7); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: dipeptidyl aminopeptidase II; dipeptidyl peptidase 2; dipeptidyl peptidase 7; dipeptidyl peptidase II; dipeptidyl-peptidase 2; dipeptidyl-peptidase II; DPP II; Dpp2; quiescent cell proline dipeptidase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,563,240 - 28,567,492 (-)NCBIGRCr8
mRatBN7.238,165,091 - 8,169,343 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,165,091 - 8,169,355 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx311,270,225 - 11,274,475 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,856,455 - 19,860,705 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0318,046,298 - 18,050,548 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,569,135 - 2,573,387 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,569,135 - 2,573,387 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,550,548 - 2,554,800 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,514,968 - 3,519,220 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.133,514,967 - 3,519,220 (-)NCBI
Celera32,991,272 - 2,995,524 (-)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 12 of 12 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dpp7RatAdams-Oliver Syndrome 5  ISODPP7 (Homo sapiens)8554872ClinVar Annotator: match by term: Adams-Oliver syndrome 5ClinVarPMID:16025100 more ...
Dpp7Ratautosomal dominant intellectual developmental disorder 8  ISODPP7 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorder with or without hyperkinetic movements and seizures and autosomal dominantClinVarPMID:28492532
Dpp7Ratautosomal dominant nocturnal frontal lobe epilepsy 5  ISODPP7 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal dominant nocturnal frontal lobe epilepsy 5ClinVarPMID:28492532
Dpp7Ratdevelopmental and epileptic encephalopathy 14  ISODPP7 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:19264732 more ...
Dpp7Ratdevelopmental and epileptic encephalopathy 14  ISODPP7 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16025100 more ...
Dpp7Ratepilepsy  ISODPP7 (Homo sapiens)8554872ClinVar Annotator: match by term: EpilepsyClinVar 
Dpp7RatJoubert syndrome 1  ISODPP7 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial aplasia of the vermisClinVarPMID:16025100 more ...
Dpp7RatKleefstra syndrome 1  ISODPP7 (Homo sapiens)8554872ClinVar Annotator: match by term: Kleefstra syndrome 1ClinVarPMID:19264732 more ...
Dpp7RatLeigh disease  ISODPP7 (Homo sapiens)8554872ClinVar Annotator: match by term: Leigh syndromeClinVarPMID:28492532
Dpp7Ratprimary coenzyme Q10 deficiency 7  ISODPP7 (Homo sapiens)8554872ClinVar Annotator: match by term: Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndromeClinVarPMID:28492532
Dpp7RatRafiq syndrome  ISODPP7 (Homo sapiens)8554872ClinVar Annotator: match by term: Rafiq syndromeClinVarPMID:24566669 more ...
Dpp7Rattuberous sclerosis 1  ISODPP7 (Homo sapiens)8554872ClinVar Annotator: match by term: Tuberous sclerosis 1ClinVarPMID:28492532
1 to 12 of 12 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dpp7RatExperimental Liver Cirrhosis  ISODPP7 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136
Dpp7RatNecrosis  ISODPP7 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16725115

1 to 20 of 88 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dpp7Rat(1->4)-beta-D-glucan multiple interactionsISODpp7 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of DPP7 mRNACTDPMID:36331819
Dpp7Rat1,2-dimethylhydrazine multiple interactionsISODpp7 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of DPP7 mRNACTDPMID:22206623
Dpp7Rat1,2-dimethylhydrazine increases expressionISODpp7 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of DPP7 mRNACTDPMID:22206623
Dpp7Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of DPP7 mRNACTDPMID:25380136
Dpp7Rat17beta-estradiol increases expressionISODPP7 (Homo sapiens)6480464Estradiol results in increased expression of DPP7 mRNACTDPMID:18556351
Dpp7Rat17beta-estradiol multiple interactionsISODpp7 (Mus musculus)6480464[Estradiol co-treated with Progesterone] results in increased expression of DPP7 mRNACTDPMID:18556351
Dpp7Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of DPP7 mRNACTDPMID:21215274 and PMID:32109520
Dpp7Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of DPP7 mRNACTDPMID:34747641
Dpp7Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISODpp7 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of DPP7 mRNACTDPMID:21570461
Dpp7Rat2,5-hexanedione multiple interactionsEXP 6480464[carbendazim co-treated with 2 and 5-hexanedione] results in decreased expression of DPP7 mRNACTDPMID:22382377
Dpp7Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of DPP7 mRNACTDPMID:28522335
Dpp7Rat4,4'-diaminodiphenylmethane increases expressionEXP 64804644 and 4'-diaminodiphenylmethane results in increased expression of DPP7 mRNACTDPMID:25380136
Dpp7Rat4,4'-sulfonyldiphenol decreases expressionISODpp7 (Mus musculus)6480464bisphenol S results in decreased expression of DPP7 mRNACTDPMID:39298647
Dpp7Rat4,4'-sulfonyldiphenol increases expressionISODPP7 (Homo sapiens)6480464bisphenol S results in increased expression of DPP7 proteinCTDPMID:34186270
Dpp7Rat4-hydroxyphenyl retinamide decreases expressionISODpp7 (Mus musculus)6480464Fenretinide results in decreased expression of DPP7 mRNACTDPMID:28973697
Dpp7Rat4-nitroaniline multiple interactionsISODPP7 (Homo sapiens)6480464[DPP7 protein results in increased cleavage of Dipeptides] which results in increased abundance of 4-nitroaniline more ...CTDPMID:16725115
Dpp7Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of DPP7 mRNACTDPMID:31881176
Dpp7Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of DPP7 mRNACTDPMID:16483693
Dpp7RatAroclor 1254 increases expressionISODpp7 (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in increased expression of DPP7 mRNACTDPMID:25270620
Dpp7Ratarsane increases expressionEXP 6480464Arsenic results in increased expression of DPP7 mRNACTDPMID:18315880

1 to 20 of 88 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dpp7Ratlysosomal protein catabolic process acts_upstream_of_or_withinISODpp7 (Mus musculus)1624291 PMID:28728022RGDPMID:28728022
Dpp7Ratlysosomal protein catabolic process acts_upstream_of_or_withinIEAUniProtKB:Q9ET22 and ensembl:ENSMUSP000000283321600115GO_REF:0000107EnsemblGO_REF:0000107
Dpp7Ratprotein catabolic process  IDA 70800 RGD 
Dpp7Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Dpp7Ratproteolysis involved_inIEAInterPro:IPR0087581600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dpp7Ratcytoplasmic vesicle located_inIEAUniProtKB-KW:KW-09681600115GO_REF:0000043UniProtGO_REF:0000043
Dpp7Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Dpp7Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Dpp7RatGolgi apparatus located_inISODPP7 (Homo sapiens)1624291 RGDGO_REF:0000052
Dpp7Ratintracellular membrane-bounded organelle located_inISODPP7 (Homo sapiens)1624291 RGDGO_REF:0000052
Dpp7Ratlysosome located_inISODpp7 (Mus musculus)1624291 PMID:29514215RGDPMID:29514215
Dpp7Ratlysosome located_inIEAUniProtKB:Q9ET22 and ensembl:ENSMUSP000000283321600115GO_REF:0000107EnsemblGO_REF:0000107
Dpp7Ratlysosome located_inIEAUniProtKB-KW:KW-04581600115GO_REF:0000043UniProtGO_REF:0000043
Dpp7Ratlysosome located_inIEAUniProtKB-SubCell:SL-01581600115GO_REF:0000044UniProtGO_REF:0000044
Dpp7Ratvesicle part_ofISODPP7 (Homo sapiens)1624291 PMID:11067927RGDPMID:11067927
Dpp7Ratvesicle is_active_inIBAPANTHER:PTN000110173 and UniProtKB:Q9UHL41600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 11 of 11 rows

Molecular Function
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dpp7Rataminopeptidase activity enablesIEAUniProtKB-KW:KW-00311600115GO_REF:0000043UniProtGO_REF:0000043
Dpp7Ratdipeptidyl-peptidase activity  IDA 70800 RGD 
Dpp7Ratdipeptidyl-peptidase activity enablesIEAUniProtKB:Q9ET22 and ensembl:ENSMUSP000000283321600115GO_REF:0000107EnsemblGO_REF:0000107
Dpp7Ratdipeptidyl-peptidase activity enablesISODpp7 (Mus musculus)1624291 PMID:28728022RGDPMID:28728022
Dpp7Ratdipeptidyl-peptidase activity enablesIBAMGI:1933213 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dpp7Ratdipeptidyl-peptidase activity enablesIEAEC:3.4.14.21600115GO_REF:0000003UniProtGO_REF:0000003
Dpp7Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Dpp7Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Dpp7Ratserine-type exopeptidase activity enablesIEAInterPro:IPR0087581600115GO_REF:0000002InterProGO_REF:0000002
Dpp7Ratserine-type peptidase activity enablesIEAUniProtKB-KW:KW-07201600115GO_REF:0000043UniProtGO_REF:0000043
1 to 10 of 10 rows


1 to 10 of 10 rows
#
Reference Title
Reference Citation
1. Purification, molecular cloning, and immunohistochemical localization of dipeptidyl peptidase II from the rat kidney and its identity with quiescent cell proline dipeptidase. Araki H, etal., J Biochem (Tokyo) 2001 Feb;129(2):279-88.
2. Cloning and functional expression of rat kidney dipeptidyl peptidase II. Fukasawa KM, etal., Biochem J 2001 Jan 15;353(Pt 2):283-90.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Gene Data Set MGD Curation, June 12, 2002
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
1 to 10 of 10 rows
PMID:11067927   PMID:15489334   PMID:23376485   PMID:23533145   PMID:29514215  



Dpp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,563,240 - 28,567,492 (-)NCBIGRCr8
mRatBN7.238,165,091 - 8,169,343 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,165,091 - 8,169,355 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx311,270,225 - 11,274,475 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,856,455 - 19,860,705 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0318,046,298 - 18,050,548 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,569,135 - 2,573,387 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,569,135 - 2,573,387 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,550,548 - 2,554,800 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,514,968 - 3,519,220 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.133,514,967 - 3,519,220 (-)NCBI
Celera32,991,272 - 2,995,524 (-)NCBICelera
Cytogenetic Map3p13NCBI
DPP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,110,546 - 137,118,306 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9137,110,542 - 137,118,309 (-)EnsemblGRCh38hg38GRCh38
GRCh379140,004,998 - 140,009,185 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,124,813 - 139,129,016 (-)NCBINCBI36Build 36hg18NCBI36
Build 349137,280,936 - 137,285,002NCBI
Celera9110,519,219 - 110,522,731 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,466,325 - 109,469,873 (-)NCBIHuRef
CHM1_19140,153,770 - 140,157,892 (-)NCBICHM1_1
T2T-CHM13v2.09149,348,484 - 149,356,230 (-)NCBIT2T-CHM13v2.0
Dpp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,242,302 - 25,246,365 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,242,288 - 25,246,371 (-)EnsemblGRCm39 Ensembl
GRCm38225,352,290 - 25,356,389 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl225,352,276 - 25,356,359 (-)EnsemblGRCm38mm10GRCm38
MGSCv37225,207,810 - 25,211,852 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36225,174,299 - 25,178,341 (-)NCBIMGSCv36mm8
Celera225,079,828 - 25,083,870 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map217.19NCBI
Dpp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555135,106,430 - 5,109,483 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555135,105,833 - 5,109,676 (+)NCBIChiLan1.0ChiLan1.0
DPP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,269,365 - 2,288,713 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan191,210,294 - 2,291,046 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,170,361 - 108,189,498 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,140,493 - 137,143,599 (-)NCBIpanpan1.1PanPan1.1panPan2
DPP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,554,062 - 48,557,752 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,554,077 - 48,557,746 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,739,358 - 47,743,048 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,414,287 - 49,417,976 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,414,287 - 49,417,961 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,190,576 - 48,194,266 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,489,346 - 48,493,035 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,536,605 - 48,540,294 (-)NCBIUU_Cfam_GSD_1.0
Dpp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,502,036 - 202,506,169 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936669869,067 - 872,885 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936669868,889 - 872,982 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPP7
(Sus scrofa - pig)
No map positions available.
DPP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,062,639 - 1,079,143 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl121,074,811 - 1,079,550 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660584,224,922 - 4,229,393 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dpp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624760826,218 - 830,636 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624760825,992 - 829,670 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Dpp7
6 total Variants

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:40
Interacting mature miRNAs:44
Transcripts:ENSRNOT00000017271
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 11 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat

1 to 10 of 11 rows
RH130913  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.238,165,104 - 8,165,307 (+)MAPPERmRatBN7.2
Rnor_6.032,569,149 - 2,569,351NCBIRnor6.0
Rnor_5.032,550,562 - 2,550,764UniSTSRnor5.0
RGSC_v3.433,514,982 - 3,515,184UniSTSRGSC3.4
Celera32,991,286 - 2,991,488UniSTS
Cytogenetic Map3p13UniSTS
RH131536  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.238,164,634 - 8,164,825 (+)MAPPERmRatBN7.2
Rnor_6.032,568,679 - 2,568,869NCBIRnor6.0
Rnor_5.032,550,092 - 2,550,282UniSTSRnor5.0
RGSC_v3.433,514,512 - 3,514,702UniSTSRGSC3.4
Celera32,990,816 - 2,991,006UniSTS
Cytogenetic Map3p13UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000017271   ⟹   ENSRNOP00000017271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl38,165,091 - 8,169,355 (-)Ensembl
Rnor_6.0 Ensembl32,569,135 - 2,573,387 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115633   ⟹   ENSRNOP00000095189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl38,165,091 - 8,169,355 (-)Ensembl
RefSeq Acc Id: NM_031973   ⟹   NP_114179
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,563,240 - 28,567,492 (-)NCBI
mRatBN7.238,165,091 - 8,169,343 (-)NCBI
Rnor_6.032,569,135 - 2,573,387 (-)NCBI
Rnor_5.032,550,548 - 2,554,800 (-)NCBI
RGSC_v3.433,514,968 - 3,519,220 (-)RGD
Celera32,991,272 - 2,995,524 (-)RGD
Sequence:
1 to 10 of 10 rows
Protein RefSeqs NP_114179 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78783 (Get FASTA)   NCBI Sequence Viewer  
  BAB11691 (Get FASTA)   NCBI Sequence Viewer  
  BAB13500 (Get FASTA)   NCBI Sequence Viewer  
  EDL93599 (Get FASTA)   NCBI Sequence Viewer  
  EDL93600 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017271
  ENSRNOP00000017271.2
  ENSRNOP00000095189.1
GenBank Protein Q9EPB1 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_114179   ⟸   NM_031973
- Peptide Label: precursor
- UniProtKB: Q9EPB1 (UniProtKB/Swiss-Prot),   A6JT47 (UniProtKB/TrEMBL),   A0A8I6AJ69 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017271   ⟸   ENSRNOT00000017271
Ensembl Acc Id: ENSRNOP00000095189   ⟸   ENSRNOT00000115633

Name Modeler Protein Id AA Range Protein Structure
AF-Q9EPB1-F1-model_v2 AlphaFold Q9EPB1 1-500 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691872
Promoter ID:EPDNEW_R2397
Type:multiple initiation site
Name:Dpp7_1
Description:dipeptidylpeptidase 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.032,573,380 - 2,573,440EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-50460 BioCyc
Ensembl Genes ENSRNOG00000012640 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017271 ENTREZGENE
  ENSRNOT00000017271.4 UniProtKB/Swiss-Prot
  ENSRNOT00000115633.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.980 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7110490 IMAGE-MGC_LOAD
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S28 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser_carbopepase_S28_SKS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93328 IMAGE-MGC_LOAD
NCBI Gene 83799 ENTREZGENE
PANTHER DIPEPTIDYL PEPTIDASE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_S28 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dpp7 PhenoGen
RatGTEx ENSRNOG00000012640 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AJ69 ENTREZGENE, UniProtKB/TrEMBL
  A6JT47 ENTREZGENE, UniProtKB/TrEMBL
  A6JT48_RAT UniProtKB/TrEMBL
  DPP2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Dpp7  dipeptidylpeptidase 7      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

Note Type Note Reference
gene_protein 500 amino acids; mature enzyme contains 464 residues with predicted molecular weight of 51 kDa 70613