Abo (ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Abo (ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase) Rattus norvegicus
Analyze
Symbol: Abo
Name: ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
RGD ID: 2307241
Description: Enables alpha-1,3-galactosyltransferase activity and glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity. Involved in several processes, including negative regulation of apoptotic process; response to nematode; and response to retinoic acid. Predicted to be located in Golgi cisterna membrane and extracellular region. Predicted to be active in Golgi apparatus and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; graft-versus-host disease; leukemia (multiple); lung disease (multiple); and severe acute respiratory syndrome. Orthologous to human ABO (ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase); PARTICIPATES IN lacto-series glycosphingolipid metabolic pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: a transferase; ABO blood group (alpha 1-3-N-acetylgalactosaminyltransferase, alpha 1-3-galactosyltransferase); ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase); Abo2; b blood group galactosyltransferase; b transferase; blood group A glycosyltransferase 2; cis-AB transferase 2; fucosylglycoprotein 3-alpha-galactosyltransferase; fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; glycoprotein-fucosylgalactoside alpha-galactosyltransferase; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; histo-blood group A transferase; histo-blood group ABO system transferase 2; histo-blood group B transferase; LOC296504; NAGAT 2; putative blood group A transferase T2; transferase B, alpha 1-3-galactosyltransferase)
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8330,560,172 - 30,604,758 (-)NCBIGRCr8
mRatBN7.2310,162,087 - 10,182,835 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl310,162,096 - 10,191,423 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx313,210,402 - 13,231,083 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0321,795,803 - 21,816,484 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0320,051,101 - 20,071,782 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.034,374,679 - 4,394,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl34,374,602 - 4,394,428 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.039,729,921 - 9,749,616 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.435,730,553 - 5,751,204 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera34,960,630 - 4,981,265 (-)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Original Reference(s)
AboRatAcute Liver Failure treatmentISOABO (Homo sapiens)39938835associated with Chronic Hepatitis B RGD 
AboRatacute lymphoblastic leukemia susceptibilityISOABO (Homo sapiens)11100012 RGD 
AboRatAdenoviridae Infections susceptibilityISOABO (Homo sapiens)39938844DNA:polymorphism:cds:allele AB (human)RGD 
AboRatasthma no_associationISOABO (Homo sapiens)5128835 RGD 
AboRatasthma  ISOABO (Homo sapiens)5128831 RGD 
AboRatCOVID-19 susceptibilityISOABO (Homo sapiens)35668862DNA:polymorphism:cds:allele A and allele O (human)RGD 
AboRatechinococcosis  ISOABO (Homo sapiens)5128834 RGD 
AboRatgallbladder carcinoma  ISOABO (Homo sapiens)2317512 RGD 
AboRatgraft-versus-host disease  ISOABO (Homo sapiens)11100006 RGD 
AboRatHematologic Neoplasms susceptibilityISOABO (Homo sapiens)11100003 RGD 
AboRathemolytic anemia  ISOABO (Homo sapiens)11100010 RGD 
AboRathepatitis susceptibilityISOABO (Homo sapiens)35668862associated with COVID-19 and DNA:polymorphism:cds:allele A (human)RGD 
AboRatHuman Influenza  ISOABO (Homo sapiens)5128836 RGD 
AboRatHuman Influenza susceptibilityISOABO (Homo sapiens)39938844DNA:polymorphism:cds:allele AB (human)RGD 
AboRathypertension susceptibilityISOABO (Homo sapiens)35668862associated with COVID-19 and DNA:polymorphism:cds:allele A (human)RGD 
AboRatleukemia susceptibilityISOABO (Homo sapiens)11100002DNA:hypermethylation:promoter:RGD 
AboRatpancreatic cancer  ISOABO (Homo sapiens)2317511 RGD 
AboRatPlasmodium falciparum malaria susceptibilityISOABO (Homo sapiens)39938831DNA:SNPs and haplotype:multipleRGD 
AboRatpneumonia severityISOABO (Homo sapiens)39938844DNA:polymorphism:cds:allele A (human)RGD 
AboRatPseudomonas Infections susceptibilityISOABO (Homo sapiens)38455983DNA:polymorphism:cds:allele B (human)RGD 
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Original Reference(s)
AboRatCoronary Disease  ISOABO (Homo sapiens)8554872ClinVar Annotator: match by term: Three Vessel Coronary DiseaseClinVarPMID:25741868
AboRatdevelopmental and epileptic encephalopathy 14  ISOABO (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 14ClinVarPMID:28492532
AboRatEhlers-Danlos syndrome classic type 1  ISOABO (Homo sapiens)8554872ClinVar Annotator: match by term: Ehlers-Danlos syndrome and classic typeClinVarPMID:28492532
AboRatLeigh disease  ISOABO (Homo sapiens)8554872ClinVar Annotator: match by term: Leigh syndromeClinVarPMID:28492532
AboRatprimary coenzyme Q10 deficiency 7  ISOABO (Homo sapiens)8554872ClinVar Annotator: match by term: Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndromeClinVarPMID:28492532
AboRatRafiq syndrome  ISOABO (Homo sapiens)8554872ClinVar Annotator: match by term: Rafiq syndromeClinVarPMID:28492532
AboRattuberous sclerosis 1  ISOABO (Homo sapiens)8554872ClinVar Annotator: match by term: Tuberous sclerosis 1ClinVarPMID:28492532
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Original Reference(s)
AboRatcoronary artery disease  ISOABO (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21378990
AboRatCOVID-19  ISOABO (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:32558485
AboRatCritical Illness  ISOABO (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:32558485
AboRatduodenal ulcer  ISOABO (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22387998
AboRatovarian carcinoma  ISOABO (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25581431
AboRatpancreatic cancer  ISOABO (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19648918 and PMID:26098869
AboRatProstatic Neoplasms  ISOABO (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17013881
AboRatrespiratory failure  ISOABO (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:32558485
AboRatStroke  ISOABO (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:29531354
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1 to 20 of 28 rows

  
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Original Reference(s)
AboRat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionEXP 64804642 more ...CTDPMID:27291303
AboRat2,3',4,4',5-Pentachlorobiphenyl increases expressionISOAbo (Mus musculus)64804642 more ...CTDPMID:31388691
AboRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOAbo (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of ABO mRNACTDPMID:21570461
AboRat2-hydroxypropanoic acid decreases expressionISOABO (Homo sapiens)6480464Lactic Acid results in decreased expression of ABO mRNACTDPMID:30851411
AboRatacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of ABO mRNACTDPMID:28959563
AboRataflatoxin B1 increases methylationISOABO (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of ABO intronCTDPMID:30157460
AboRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of ABO mRNACTDPMID:16483693
AboRatbenzo[a]pyrene increases methylationISOABO (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of ABO promoterCTDPMID:27901495
AboRatbenzo[a]pyrene affects methylationISOABO (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of ABO intronCTDPMID:30157460
AboRatbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of ABO mRNACTDPMID:25181051
AboRatcadmium dichloride increases methylationEXP 6480464Cadmium Chloride results in increased methylation of ABO promoterCTDPMID:22457795
AboRatCGP 52608 multiple interactionsISOABO (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to ABO gene]CTDPMID:28238834
AboRatchlordecone increases expressionISOAbo (Mus musculus)6480464Chlordecone results in increased expression of ABO mRNACTDPMID:33711761
AboRatchlorpyrifos decreases expressionISOAbo (Mus musculus)6480464Chlorpyrifos results in decreased expression of ABO mRNACTDPMID:32715474
AboRatflavonoids decreases expressionEXP 6480464Flavonoids results in decreased expression of ABO mRNACTDPMID:18035473
AboRatfuran increases expressionEXP 6480464furan results in increased expression of ABO mRNACTDPMID:27387713
AboRatgentamycin decreases expressionEXP 6480464Gentamicins results in decreased expression of ABO mRNACTDPMID:22061828
AboRatMuraglitazar increases expressionEXP 6480464muraglitazar results in increased expression of ABO mRNACTDPMID:21515302
AboRatparacetamol decreases expressionISOABO (Homo sapiens)6480464Acetaminophen results in decreased expression of ABO mRNACTDPMID:22230336
AboRatparaquat increases expressionEXP 6480464Paraquat results in increased expression of ABO mRNACTDPMID:32680482

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Biological Process
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Original Reference(s)
AboRatcarbohydrate metabolic process involved_inIEAInterPro:IPR0050761600115GO_REF:0000002InterProGO_REF:0000002
AboRatcarbohydrate metabolic process involved_inISOABO (Homo sapiens)1624291 PMID:15987364RGDPMID:15987364
AboRatlipid glycosylation involved_inIBAPANTHER:PTN000049004 and A3galt2 (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
AboRatnegative regulation of apoptotic process  IMP 2315741 RGD 
AboRatoligosaccharide biosynthetic process involved_inISOAbo (Mus musculus)1624291 PMID:11278752RGDPMID:11278752
AboRatpositive regulation of cell population proliferation  IMP 2315741resistance of tumor cells to immune systemRGD 
AboRatprotein glycosylation involved_inIEAUniPathway:UPA003781600115GO_REF:0000041UniProtGO_REF:0000041
AboRatresponse to nematode  IEP 625392 RGD 
AboRatresponse to retinoic acid  IEP 1600915 RGD 
1 to 9 of 9 rows

Cellular Component

  
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Original Reference(s)
AboRatextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
AboRatGolgi apparatus is_active_inIBAPANTHER:PTN000049004 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
AboRatGolgi cisterna membrane located_inIEAUniProtKB-SubCell:SL-01361600115GO_REF:0000044UniProtGO_REF:0000044
AboRatmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
AboRatvesicle is_active_inIBAPANTHER:PTN000049004 and A3galt2 (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
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Imported Annotations - KEGG (archival)

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Original Reference(s)
AboRatlacto-series glycosphingolipid metabolic pathway  IEA 6907045 KEGGrno:00601

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#
Reference Title
Reference Citation
1. Distribution of ABO blood groups in childhood acute leukemia. Alavi S, etal., Pediatr Hematol Oncol. 2006 Dec;23(8):611-7.
2. ABO compatibility and acute graft-versus-host disease following allogeneic bone marrow transplantation. Bacigalupo A, etal., Transplantation. 1988 Jun;45(6):1091-4.
3. Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease. Banales JM, etal., Am J Pathol. 2008 Dec;173(6):1637-46. Epub 2008 Nov 6.
4. DNA methylation of the ABO promoter underlies loss of ABO allelic expression in a significant proportion of leukemic patients. Bianco-Miotto T, etal., PLoS One. 2009;4(3):e4788. doi: 10.1371/journal.pone.0004788. Epub 2009 Mar 10.
5. Lack of association between asthma and ABO blood group. Bijanzadeh M, etal., Lung. 2009 Nov-Dec;187(6):389-92. Epub 2009 Sep 22.
6. Influence of infectious diseases on hereditary polymorphism with respect to the blood groups of the ABO system. Bubnov YI, etal., Sov Genet. 1974 Nov 15;9(1):105-8.
7. ABO/secretor genetic complex is associated with the susceptibility of childhood asthma in Taiwan. Chen YL, etal., Clin Exp Allergy. 2005 Jul;35(7):926-32.
8. ABO blood group and susceptibility to severe acute respiratory syndrome. Cheng Y, etal., JAMA. 2005 Mar 23;293(12):1450-1.
9. [The distribution of ABO system blood groups in patients with unilocular echinococcosis]. Chobanov RE and Salekhov AA, Med Parazitol (Mosk). 1990 Mar-Apr;(2):18-20.
10. [Correlations of the antigenic specificity of human blood with the levels of antihemagglutinins to influenza viruses]. Fedorova GI, etal., Vopr Virusol. 1983 Jan-Feb;28(1):54-7.
11. Microarray analysis of retinoid-dependent gene activity during rat embryogenesis: increased collagen fibril production in a model of retinoid insufficiency. Flentke GR, etal., Dev Dyn. 2004 Apr;229(4):886-98.
12. Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria. Fry AE, etal., Hum Mol Genet. 2008 Feb 15;17(4):567-76. doi: 10.1093/hmg/ddm331. Epub 2007 Nov 13.
13. Enzymes that synthesize the IB4 epitope are not sufficient to impart IB4 binding in dorsal root ganglia of rat. Fullmer JM, etal., J Comp Neurol. 2007 Mar 1;501(1):70-82.
14. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
15. Induction of red blood cell destruction by graft-derived antibodies after minor ABO-mismatched heart and lung transplantation. Hunt BJ, etal., Transplantation. 1988 Aug;46(2):246-9.
16. [Clinical efficacies of ABO-incompatible adult liver transplantation]. Ju WQ, etal., Zhonghua Yi Xue Za Zhi. 2011 Sep 27;91(36):2558-60.
17. The clinical implications of ABO blood groups in Pseudomonas aeruginosa sepsis in children. Kuo KC, etal., J Microbiol Immunol Infect. 2013 Apr;46(2):109-14. doi: 10.1016/j.jmii.2012.01.003. Epub 2012 Mar 29.
18. Association between ABO blood groups and risk of SARS-CoV-2 pneumonia. Li J, etal., Br J Haematol. 2020 Jul;190(1):24-27. doi: 10.1111/bjh.16797. Epub 2020 May 26.
19. Expression of histo-blood group A antigen increases resistance to apoptosis and facilitates escape from immune control of rat colon carcinoma cells. Marionneau S, etal., Glycobiology. 2002 Dec;12(12):851-6.
20. Blood group A glycosyltransferase occurring as alleles with high sequence difference is transiently induced during a Nippostrongylus brasiliensis parasite infection. Olson FJ, etal., J Biol Chem 2002 Apr 26;277(17):15044-52.
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PMID:11278752   PMID:12180981   PMID:12198488   PMID:12237302  



Abo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8330,560,172 - 30,604,758 (-)NCBIGRCr8
mRatBN7.2310,162,087 - 10,182,835 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl310,162,096 - 10,191,423 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx313,210,402 - 13,231,083 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0321,795,803 - 21,816,484 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0320,051,101 - 20,071,782 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.034,374,679 - 4,394,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl34,374,602 - 4,394,428 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.039,729,921 - 9,749,616 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.435,730,553 - 5,751,204 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera34,960,630 - 4,981,265 (-)NCBICelera
Cytogenetic Map3p13NCBI
ABO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389133,250,401 - 133,275,201 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9133,233,278 - 133,276,024 (-)EnsemblGRCh38hg38GRCh38
GRCh379136,125,788 - 136,150,617 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369135,120,384 - 135,140,451 (-)NCBINCBI36Build 36hg18NCBI36
Build 349133,160,116 - 133,180,184NCBI
Celera9106,672,476 - 106,692,536 (-)NCBICelera
Cytogenetic Map9q34.2NCBI
HuRef9105,623,316 - 105,642,515 (-)NCBIHuRef
CHM1_19136,280,691 - 136,300,722 (-)NCBICHM1_1
T2T-CHM13v2.09145,463,984 - 145,489,076 (-)NCBIT2T-CHM13v2.0
Abo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,732,508 - 26,754,973 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,732,515 - 26,754,991 (-)EnsemblGRCm39 Ensembl
GRCm38226,842,496 - 26,864,995 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,842,503 - 26,864,979 (-)EnsemblGRCm38mm10GRCm38
MGSCv37226,698,023 - 26,720,499 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36226,664,512 - 26,686,988 (-)NCBIMGSCv36mm8
Celera226,552,235 - 26,574,718 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.06NCBI
ABO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2116,077,519 - 6,122,488 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan196,079,855 - 6,124,240 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09104,354,115 - 104,399,057 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19132,989,574 - 132,997,271 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9132,989,574 - 133,010,324 (-)Ensemblpanpan1.1panPan2
ABO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1949,746,749 - 49,758,317 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl949,748,693 - 49,758,479 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha949,003,262 - 49,012,806 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0950,622,683 - 50,632,476 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl950,622,856 - 50,632,740 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1949,385,323 - 49,394,880 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0949,699,814 - 49,709,357 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0949,804,746 - 49,814,294 (-)NCBIUU_Cfam_GSD_1.0
Abo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,324,312 - 10,330,690 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365701,315,192 - 1,322,719 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11272,912,239 - 272,935,316 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ABO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1124,863,100 - 4,892,204 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl124,863,165 - 4,885,849 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607910,775,478 - 10,796,102 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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Variants in Abo
154 total Variants


Assembly: RGSC_v3.4
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
3 5734371 5734372 G A snv LCR/1Mco (UMich), HCR/1Mco (UMich) View more Information


Assembly: Rnor_5.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
3 9730856 9730857 C T snv IS-Tlk/Kyo (KyushuU), IS/Kyo (KyushuU) View more Information
3 9731015 9731016 C T snv DOB/Oda (KyushuU) View more Information
3 9733257 9733258 G A snv IS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU) View more Information


Assembly: Rnor_6.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
3 4375505 4375506 C T snv ACI/EurMcwi (2019) View more Information
3 4375773 4375774 C T snv ACI/EurMcwi (2019), DA/OlaHsd (2019), ACI/EurMcwi (MCW) View more Information
3 4378015 4378016 G A snv SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), WKY/NCrl (2019), HXB4/IpcvMcwi (2020), HXB31/IpcvMcwi (2019), WKY/N (2020), BXH2/CubMcwi (2020), HXB10/IpcvMcwi (2019) View more Information

Predicted Target Of
Summary Value
Count of predictions:291
Count of miRNA genes:194
Interacting mature miRNAs:222
Transcripts:ENSRNOT00000044775
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 15 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat

1 to 10 of 15 rows
RH132268  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2310,162,172 - 10,162,384 (+)MAPPERmRatBN7.2
mRatBN7.2310,028,107 - 10,028,319 (-)MAPPERmRatBN7.2
Rnor_6.035,386,026 - 5,386,237NCBIRnor6.0
Rnor_6.034,374,754 - 4,374,965NCBIRnor6.0
Rnor_5.039,729,996 - 9,730,207UniSTSRnor5.0
Rnor_5.0310,737,095 - 10,737,306UniSTSRnor5.0
RGSC_v3.435,596,564 - 5,596,775UniSTSRGSC3.4
RGSC_v3.435,730,628 - 5,730,839UniSTSRGSC3.4
Celera34,960,705 - 4,960,916UniSTS
Celera34,829,378 - 4,829,589UniSTS
Cytogenetic Map3p12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 90 89 58 25 58 6 217 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000044775   ⟹   ENSRNOP00000039997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl310,162,099 - 10,182,799 (-)Ensembl
Rnor_6.0 Ensembl34,374,602 - 4,394,428 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000072025   ⟹   ENSRNOP00000067875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl310,162,096 - 10,168,647 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095709   ⟹   ENSRNOP00000095872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl310,162,096 - 10,168,505 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115517   ⟹   ENSRNOP00000077138
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl310,162,096 - 10,191,423 (-)Ensembl
RefSeq Acc Id: NM_001160263   ⟹   NP_001153735
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8330,560,174 - 30,580,876 (-)NCBI
mRatBN7.2310,162,095 - 10,182,799 (-)NCBI
Rnor_6.034,374,679 - 4,394,374 (-)NCBI
Rnor_5.039,729,921 - 9,749,616 (-)NCBI
RGSC_v3.435,730,553 - 5,751,204 (-)RGD
Celera34,960,630 - 4,981,265 (-)RGD
Sequence:
RefSeq Acc Id: XM_039104075   ⟹   XP_038960003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8330,560,172 - 30,580,909 (-)NCBI
mRatBN7.2310,162,087 - 10,182,835 (-)NCBI
RefSeq Acc Id: XM_063282943   ⟹   XP_063139013
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8330,560,172 - 30,604,758 (-)NCBI
RefSeq Acc Id: XM_063282944   ⟹   XP_063139014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8330,560,172 - 30,579,185 (-)NCBI
RefSeq Acc Id: XM_063282945   ⟹   XP_063139015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8330,560,172 - 30,604,725 (-)NCBI
RefSeq Acc Id: XM_063282946   ⟹   XP_063139016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8330,560,172 - 30,604,693 (-)NCBI
RefSeq Acc Id: XM_063282947   ⟹   XP_063139017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8330,560,172 - 30,579,185 (-)NCBI
1 to 5 of 11 rows
1 to 5 of 11 rows
RefSeq Acc Id: NP_001153735   ⟸   NM_001160263
- UniProtKB: Q8CFC4 (UniProtKB/Swiss-Prot),   A6JTH9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000039997   ⟸   ENSRNOT00000044775
RefSeq Acc Id: XP_038960003   ⟸   XM_039104075
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000077138   ⟸   ENSRNOT00000115517
Ensembl Acc Id: ENSRNOP00000067875   ⟸   ENSRNOT00000072025

Name Modeler Protein Id AA Range Protein Structure
AF-Q8CFC4-F1-model_v2 AlphaFold Q8CFC4 1-334 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 23 of 23 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-50333 BioCyc
Ensembl Genes ENSRNOG00000046958 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044775.5 UniProtKB/Swiss-Prot
  ENSRNOT00000072025.3 UniProtKB/TrEMBL
  ENSRNOT00000095709.1 UniProtKB/TrEMBL
  ENSRNOT00000115517.1 UniProtKB/TrEMBL
Gene3D-CATH Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glyco_trans_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:100301568 UniProtKB/Swiss-Prot
NCBI Gene 100301568 ENTREZGENE
PANTHER HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10462 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glyco_transf_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Abo PhenoGen
RatGTEx ENSRNOG00000046958 RatGTEx
Superfamily-SCOP SSF53448 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y5Y8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMH2_RAT UniProtKB/TrEMBL
  A6JTH9 ENTREZGENE, UniProtKB/TrEMBL
  BGAT2_RAT UniProtKB/Swiss-Prot
  M0RE11_RAT UniProtKB/TrEMBL
  Q8CFC4 ENTREZGENE
1 to 23 of 23 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-26 Abo  ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase  Abo  ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-05-22 Abo2  histo-blood group ABO system transferase 2      Symbol and Name status set to provisional 70820 PROVISIONAL