Gene: Robo4 (roundabout guidance receptor 4) Rattus norvegicus
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Symbol: Robo4
Name: roundabout guidance receptor 4
Description: ENCODES a protein that exhibits signaling receptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); negative regulation of cell migration (ortholog); signal transduction (ortholog); ASSOCIATED WITH aortic valve disease (ortholog); autistic disorder (ortholog); bicuspid aortic valve disease (ortholog); FOUND IN external side of plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; benzo[a]pyrene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Magic roundabout; roundabout homolog 4; roundabout homolog 4 (Drosophila); roundabout homolog 4 (drosophilia); roundabout, axon guidance receptor, homolog 4; roundabout, axon guidance receptor, homolog 4 (Drosophila)
Orthologs:
Homo sapiens (human) : ROBO4 (roundabout guidance receptor 4)  HGNC  Alliance
Mus musculus (house mouse) : Robo4 (roundabout guidance receptor 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Robo4 (roundabout guidance receptor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ROBO4 (roundabout guidance receptor 4)
Canis lupus familiaris (dog) : ROBO4 (roundabout guidance receptor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Robo4 (roundabout guidance receptor 4)
Sus scrofa (pig) : ROBO4 (roundabout guidance receptor 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: GeneIDs: 100911068 and 300518 are annotated independently on Rnor_6.0 (Annotation Release 105) but may be redundant loci. [24 Feb 2015]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0839,082,693 - 39,093,344 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0839,089,746 - 39,099,696 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,655,072 - 38,665,022 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1838,663,837 - 38,673,788 (+)NCBI
Celera837,322,941 - 37,332,891 (-)NCBICelera
Cytogenetic Map8q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Robo4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 727947
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE