LOC119618083 (HLA class II histocompatibility antigen, DRB1 beta chain-like) - Rat Genome Database

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Gene: LOC119618083 (HLA class II histocompatibility antigen, DRB1 beta chain-like) Chlorocebus sabaeus
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Symbol: LOC119618083
Name: HLA class II histocompatibility antigen, DRB1 beta chain-like
RGD ID: 40896464
Description: ENCODES a protein that exhibits CD4 receptor binding (inferred); MHC class II receptor activity (inferred); peptide antigen binding (inferred); INVOLVED IN adaptive immune response (inferred); antigen processing and presentation (inferred); antigen processing and presentation of endogenous peptide antigen via MHC class II (inferred); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); immunological synapse (inferred)
Type: protein-coding
RefSeq Status: MODEL
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366615549,411 - 62,465 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response  (IEA)
antigen processing and presentation  (IEA)
antigen processing and presentation of endogenous peptide antigen via MHC class II  (IEA)
antigen processing and presentation of exogenous peptide antigen via MHC class II  (IEA)
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II  (IEA)
detection of bacterium  (IEA)
humoral immune response  (IEA)
immune response  (IEA)
inflammatory response to antigenic stimulus  (IEA)
macrophage differentiation  (IEA)
myeloid dendritic cell antigen processing and presentation  (IEA)
negative regulation of inflammatory response to antigenic stimulus  (IEA)
negative regulation of T cell proliferation  (IEA)
negative regulation of type II interferon production  (IEA)
peptide antigen assembly with MHC class II protein complex  (IEA)
positive regulation of canonical NF-kappaB signal transduction  (IEA)
positive regulation of CD4-positive, alpha-beta T cell activation  (IEA)
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation  (IEA)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of ERK1 and ERK2 cascade  (IEA)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (IEA)
positive regulation of MAPK cascade  (IEA)
positive regulation of memory T cell differentiation  (IEA)
positive regulation of monocyte differentiation  (IEA)
positive regulation of T cell mediated cytotoxicity  (IEA)
positive regulation of T cell mediated immune response to tumor cell  (IEA)
positive regulation of viral entry into host cell  (IEA)
protein tetramerization  (IEA)
regulation of interleukin-10 production  (IEA)
regulation of interleukin-4 production  (IEA)
regulation of T-helper cell differentiation  (IEA)
signal transduction  (IEA)
T cell receptor signaling pathway  (IEA)
T-helper 1 type immune response  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_037995561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_037995561   ⟹   XP_037851489
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366615549,411 - 62,465 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037851489 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000005635.1
RefSeq Acc Id: XP_037851489   ⟸   XM_037995561
- UniProtKB: A0A0D9RAJ6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009383 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007457.1 UniProtKB/TrEMBL
Gene3D-CATH Immunoglobulins UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC/Immunoglobulin UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_II_a/b_N UniProtKB/TrEMBL
  MHC_II_b_N UniProtKB/TrEMBL
NCBI Gene LOC119618083 ENTREZGENE
PANTHER HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1 BETA CHAIN UniProtKB/TrEMBL
  MHC CLASS II-RELATED UniProtKB/TrEMBL
Pfam C1-set UniProtKB/TrEMBL
  MHC_II_beta UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
SMART IGc1 UniProtKB/TrEMBL
  MHC_II_beta UniProtKB/TrEMBL
Superfamily-SCOP Immunoglobulin UniProtKB/TrEMBL
  MHC antigen-recognition domain UniProtKB/TrEMBL
UniProt A0A0D9RAJ6 ENTREZGENE, UniProtKB/TrEMBL