LOC108169208 (Pomc promoter region) - Rat Genome Database

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Gene: LOC108169208 (Pomc promoter region) Mus musculus
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Symbol: LOC108169208
Name: Pomc promoter region
RGD ID: 39130088
Description: This region represents the proximal promoter of the proopiomelanocortin (Pomc) gene. This region is stimulated by binding of signal transducer and activator of transcription 3 (Stat3) and RELA proto-oncogene, NF-kB subunit. Methylation of this region results in association by methyl-CpG binding protein 2 and epigenetic suppression of transcription. [provided by RefSeq, Jun 2016]
Type: biological-region
RefSeq Status: REVIEWED
Previously known as: Rr366691
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39124,004,447 - 4,005,032 (+)NCBIGRCm39GRCm39mm39
GRCm38123,954,447 - 3,955,032 (+)NCBIGRCm38GRCm38mm10GRCm38
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:6303853   PMID:6314261   PMID:8284022   PMID:15064421   PMID:15761497   PMID:17023536   PMID:17038560   PMID:17043312   PMID:17698954   PMID:21609458   PMID:22166984   PMID:23337531  
PMID:23370526   PMID:24078059   PMID:24379351   PMID:24506071   PMID:25510553   PMID:25936720   PMID:26792828   PMID:27217481  


Genomics

Comparative Map Data
LOC108169208
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39124,004,447 - 4,005,032 (+)NCBIGRCm39GRCm39mm39
GRCm38123,954,447 - 3,955,032 (+)NCBIGRCm38GRCm38mm10GRCm38
LOC108167315
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38225,168,454 - 25,169,266 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37225,391,323 - 25,392,135 (+)NCBIGRCh37GRCh37hg19GRCh37
T2T-CHM13v2.0225,202,908 - 25,203,720 (+)NCBIT2T-CHM13v2.0

Variants

.
Variants in LOC108169208
28 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884410Bzwq15_mbi-zygomatic width QTL 15, 16 week (mouse)12365000029749999Mouse
1301393Dyscalc3_mdystrophic cardiac calcinosis 3 (mouse)Not determined12122418579Mouse
12910983Pifs1_mpeptide-induced fatal syndrome 1 (mouse)12130433078Mouse
4141436Chldq7_mcholesterol and HDL QTL 7 (mouse)Not determined12127920733Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1234013434340302Mouse
1301143Skull17_mskull morphology 17 (mouse)Not determined12122418579Mouse
1301655Bmd12_mbone mineral density 12 (mouse)Not determined12124662697Mouse
1301207Circp1_mcircadian photosensitivity 1 (mouse)Not determined12133430339Mouse
11039525Tbbr2_mTrypanosoma brucei brucei response 2 (mouse)12122418579Mouse
4141296Femwf9_mfemur work to failure 9 (mouse)Not determined127920733Mouse
1301925Ath6_matherosclerosis 6 (mouse)Not determined12132758756Mouse
1357519Vtbt12_mvertebral trabecular bone trait 12 (mouse)Not determined12124662697Mouse
10402496Lmr22_mleishmaniasis resistance 22 (mouse)Not determined12122418579Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_050906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC111092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information

Database Acc Id Source(s)
NCBI Gene LOC108169208 ENTREZGENE
PhenoGen LOC108169208 PhenoGen