Krtap2-20 (keratin associated protein 2-20) - Rat Genome Database

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Gene: Krtap2-20 (keratin associated protein 2-20) Mus musculus
Analyze
Symbol: Krtap2-20
Name: keratin associated protein 2-20
RGD ID: 2314810
MGI Page MGI
Description: Orthologous to several human genes including KRTAP2-1 (keratin associated protein 2-1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gm11562; keratin associated protein 2-4-like; MGC157549; OTTMUSG00000002199
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,510,424 - 99,511,230 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,510,445 - 99,511,261 (-)EnsemblGRCm39 Ensembl
GRCm381199,619,598 - 99,620,404 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1199,619,619 - 99,620,435 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,480,920 - 99,481,686 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361199,481,276 - 99,481,686 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1162.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Krtap2-20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,510,424 - 99,511,230 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,510,445 - 99,511,261 (-)EnsemblGRCm39 Ensembl
GRCm381199,619,598 - 99,620,404 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1199,619,619 - 99,620,435 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,480,920 - 99,481,686 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361199,481,276 - 99,481,686 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1162.96NCBI
KRTAP2-2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,054,498 - 41,055,230 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,054,498 - 41,055,230 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,210,750 - 39,211,482 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,464,618 - 36,465,047 (-)NCBINCBI36Build 36hg18NCBI36
Celera1735,872,354 - 35,873,172 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,005,581 - 35,006,309 (-)NCBIHuRef
CHM1_11739,446,094 - 39,446,822 (-)NCBICHM1_1
T2T-CHM13v2.01741,919,008 - 41,919,845 (-)NCBIT2T-CHM13v2.0

Variants

.
Variants in Krtap2-20
18 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:109
Interacting mature miRNAs:110
Transcripts:ENSMUST00000073853
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001177537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL590997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000073853   ⟹   ENSMUSP00000073519
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1199,510,445 - 99,511,261 (-)Ensembl
GRCm38.p6 Ensembl1199,619,619 - 99,620,435 (-)Ensembl
RefSeq Acc Id: NM_001177537   ⟹   NP_001171008
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391199,510,424 - 99,511,230 (-)NCBI
GRCm381199,619,598 - 99,620,404 (-)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001171008 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000073519
  ENSMUSP00000073519.3
RefSeq Acc Id: NP_001171008   ⟸   NM_001177537
- UniProtKB: A0PK51 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000073519   ⟸   ENSMUST00000073853

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0PK51-F1-model_v2 AlphaFold A0PK51 1-136 view protein structure

Promoters
RGD ID:8676600
Promoter ID:EPDNEW_M16331
Type:multiple initiation site
Name:Gm11562_1
Description:Mus musculus predicted gene 11562 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381199,620,432 - 99,620,492EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3652059 AgrOrtholog
Ensembl Genes ENSMUSG00000062278 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000073853 ENTREZGENE
  ENSMUST00000073853.3 UniProtKB/TrEMBL
InterPro Keratin_B2 UniProtKB/TrEMBL
  KRTAP_type_2 UniProtKB/TrEMBL
KEGG Report mmu:100502803 UniProtKB/TrEMBL
MGD MGI:3652059 ENTREZGENE
NCBI Gene Krtap2-20 ENTREZGENE
PANTHER KERATIN-ASSOCIATED PROTEIN 2-1 UniProtKB/TrEMBL
  KERATIN-ASSOCIATED PROTEIN 2-1 UniProtKB/TrEMBL
Pfam Keratin_B2_2 UniProtKB/TrEMBL
PhenoGen Krtap2-20 PhenoGen
UniProt A0PK51 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-02-19 Krtap2-20  keratin associated protein 2-20  Gm11562  predicted gene 11562  Symbol and/or name updated 27372883 PROVISIONAL