Sprr2a2 (small proline-rich protein 2A2) - Rat Genome Database

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Gene: Sprr2a2 (small proline-rich protein 2A2) Mus musculus
Analyze
Symbol: Sprr2a2
Name: small proline-rich protein 2A2
RGD ID: 2313363
MGI Page MGI
Description: Is expressed in stomach and thymus primordium.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC19134; small proline-rich protein 2A; Small proline-rich protein 2A1; Small proline-rich protein 2A3; Sprr2a; Sprr2a1; Sprr2a3
RGD Orthologs
Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39392,157,982 - 92,164,610 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl392,123,227 - 92,164,031 (+)EnsemblGRCm39 Ensembl
GRCm38392,250,647 - 92,257,304 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl392,215,920 - 92,256,724 (+)EnsemblGRCm38mm10GRCm38
MGSCv37392,054,569 - 92,061,226 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera394,790,455 - 94,793,871 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map340.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9888996   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12584609   PMID:16141072   PMID:16141073   PMID:21267068   PMID:34735226  


Genomics

Comparative Map Data
Sprr2a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39392,157,982 - 92,164,610 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl392,123,227 - 92,164,031 (+)EnsemblGRCm39 Ensembl
GRCm38392,250,647 - 92,257,304 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl392,215,920 - 92,256,724 (+)EnsemblGRCm38mm10GRCm38
MGSCv37392,054,569 - 92,061,226 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera394,790,455 - 94,793,871 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map340.14NCBI
Sprr2a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82180,415,180 - 180,415,485 (+)NCBIGRCr8
mRatBN7.22177,719,576 - 177,719,845 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2177,719,576 - 177,719,845 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.02192,147,229 - 192,148,625 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2192,147,998 - 192,148,267 (+)EnsemblRnor6.0rn6Rnor6.0
Celera2172,525,572 - 172,526,968 (-)NCBICelera
Cytogenetic Map2q34NCBI

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:946
Count of miRNA genes:532
Interacting mature miRNAs:597
Transcripts:ENSMUST00000071805, ENSMUST00000090871
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
1301398Rapop3_mradiation-induced apoptosis 3 (mouse)Not determined390511217100464137Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369625509100655290Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse
10766455Sle22_msystematic lupus erythematosus susceptibility 22 (mouse)390376936124377072Mouse
14747001Mancz4_mmandible centroid size 4 (mouse)390378017124378017Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389139967137453008Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35890730792907307Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
1302052Etohcta4_methanol conditioned taste aversion 4 (mouse)Not determined391000105125008748Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000071805   ⟹   ENSMUSP00000102950
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl392,158,054 - 92,164,031 (+)Ensembl
GRCm38.p6 Ensembl392,250,747 - 92,256,724 (+)Ensembl
Ensembl Acc Id: ENSMUST00000090871   ⟹   ENSMUSP00000088386
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl392,123,227 - 92,161,871 (+)Ensembl
GRCm38.p6 Ensembl392,215,920 - 92,254,564 (+)Ensembl
RefSeq Acc Id: NM_001164787   ⟹   NP_001158259
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39392,157,982 - 92,164,610 (+)NCBI
GRCm38392,250,647 - 92,257,304 (+)ENTREZGENE
MGSCv37392,054,569 - 92,061,226 (+)RGD
Celera394,790,455 - 94,793,871 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001158259 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH10818 (Get FASTA)   NCBI Sequence Viewer  
  BAB25355 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000083330.5
  ENSMUSP00000088386.3
  ENSMUSP00000088387.5
  ENSMUSP00000102950
  ENSMUSP00000102950.2
  ENSMUSP00000142110.2
GenBank Protein Q9CQK8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001158259   ⟸   NM_001164787
- UniProtKB: O70553 (UniProtKB/Swiss-Prot),   Q9CQK8 (UniProtKB/Swiss-Prot),   Q4KL71 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000102950   ⟸   ENSMUST00000071805
Ensembl Acc Id: ENSMUSP00000088386   ⟸   ENSMUST00000090871

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KL71-F1-model_v2 AlphaFold Q4KL71 1-83 view protein structure
AF-Q9CQK8-F1-model_v2 AlphaFold Q9CQK8 1-83 view protein structure

Promoters
RGD ID:6881382
Promoter ID:EPDNEW_M4142
Type:multiple initiation site
Name:Sprr2a1_2
Description:Mus musculus small proline-rich protein 2A1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4144  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38392,250,675 - 92,250,735EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000068893 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSG00000074445 UniProtKB/Swiss-Prot
  ENSMUSG00000078664 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000071805 ENTREZGENE
  ENSMUST00000071805.4 UniProtKB/Swiss-Prot
  ENSMUST00000074449.7 UniProtKB/Swiss-Prot
  ENSMUST00000090871.3 UniProtKB/Swiss-Prot
  ENSMUST00000090872.7 UniProtKB/Swiss-Prot
  ENSMUST00000193337.2 UniProtKB/Swiss-Prot
InterPro SPRR2 UniProtKB/Swiss-Prot
KEGG Report mmu:100042514 UniProtKB/Swiss-Prot
  mmu:100303744 UniProtKB/Swiss-Prot
  mmu:20755 UniProtKB/Swiss-Prot
MGD MGI:3845026 ENTREZGENE
NCBI Gene 100303744 ENTREZGENE
Pfam SPRR2 UniProtKB/Swiss-Prot
PhenoGen Sprr2a2 PhenoGen
PRINTS PRORICH UniProtKB/Swiss-Prot
UniProt O70553 ENTREZGENE
  Q4KL71 ENTREZGENE
  Q9CQK8 ENTREZGENE
  SP2A3_MOUSE UniProtKB/Swiss-Prot
  SPR2A_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary O70553 UniProtKB/Swiss-Prot