Krtap4-21 (keratin associated protein 4-21) - Rat Genome Database

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Gene: Krtap4-21 (keratin associated protein 4-21) Mus musculus
Analyze
No known orthologs.
Symbol: Krtap4-21 (Ensembl: Gm11569)
Name: keratin associated protein 4-21 (Ensembl:predicted gene 11569)
RGD ID: 2301650
MGI Page MGI
Description: Orthologous to human KRTAP4-3 (keratin associated protein 4-3) and KRTAP4-9 (keratin associated protein 4-9).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Gm11569; keratin associated protein 4 family member
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,688,890 - 99,689,758 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,688,890 - 99,689,758 (-)EnsemblGRCm39 Ensembl
GRCm381199,798,064 - 99,798,932 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1199,798,064 - 99,798,932 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,659,378 - 99,660,246 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361199,659,387 - 99,660,250 (-)NCBIMGSCv36mm8
Celera11110,425,829 - 110,426,727 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Krtap4-21
21 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:97
Count of miRNA genes:90
Interacting mature miRNAs:94
Transcripts:ENSMUST00000105057
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
13513918Heal55_mwound healing/ regeneration 55 (mouse)1199672251100232454Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001099312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL590997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000105057   ⟹   ENSMUSP00000100678
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1199,688,890 - 99,689,758 (-)Ensembl
GRCm38.p6 Ensembl1199,798,064 - 99,798,932 (-)Ensembl
RefSeq Acc Id: NM_001099312   ⟹   NP_001092782
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391199,688,890 - 99,689,758 (-)NCBI
GRCm381199,798,064 - 99,798,932 (-)ENTREZGENE
MGSCv371199,659,378 - 99,660,246 (-)RGD
Celera11110,425,829 - 110,426,727 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001092782 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000100678
  ENSMUSP00000100678.2
Reference Protein Sequences
RefSeq Acc Id: NP_001092782   ⟸   NM_001099312
- UniProtKB: B1AQB1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000100678   ⟸   ENSMUST00000105057

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1AQB1-F1-model_v2 AlphaFold B1AQB1 1-180 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3709346 AgrOrtholog
Ensembl Genes ENSMUSG00000078260 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000105057 ENTREZGENE
  ENSMUST00000105057.2 UniProtKB/TrEMBL
InterPro Keratin_B2 UniProtKB/TrEMBL
KEGG Report mmu:670472 UniProtKB/TrEMBL
MGD MGI:3709346 ENTREZGENE
NCBI Gene 670472 ENTREZGENE
PANTHER KERATIN-ASSOCIATED PROTEIN 4-11-RELATED UniProtKB/TrEMBL
  Keratin_B2 UniProtKB/TrEMBL
Pfam Keratin_B2_2 UniProtKB/TrEMBL
PhenoGen Krtap4-21 PhenoGen
UniProt B1AQB1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-02-19 Krtap4-21  keratin associated protein 4-21  Gm11569  predicted gene 11569  Symbol and/or name updated 27372883 PROVISIONAL