UBR7 (ubiquitin protein ligase E3 component n-recognin 7) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: UBR7 (ubiquitin protein ligase E3 component n-recognin 7) Chlorocebus sabaeus
Analyze
Symbol: UBR7
Name: ubiquitin protein ligase E3 component n-recognin 7
RGD ID: 18747741
Description: ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); protein ubiquitination (inferred); ASSOCIATED WITH achondrogenesis type IA (ortholog); Developmental Disabilities (ortholog); DICER1 syndrome (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: putative E3 ubiquitin-protein ligase UBR7; ubiquitin protein ligase E3 component n-recognin 7 (putative)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12470,945,412 - 70,969,489 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2470,945,629 - 70,969,594 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605358,191,647 - 58,221,084 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UBR7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12470,945,412 - 70,969,489 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2470,945,629 - 70,969,594 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605358,191,647 - 58,221,084 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
UBR7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381493,207,256 - 93,229,215 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1493,207,241 - 93,229,215 (+)EnsemblGRCh38hg38GRCh38
GRCh371493,673,601 - 93,695,561 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361492,743,154 - 92,765,314 (+)NCBINCBI36Build 36hg18NCBI36
Build 341492,743,169 - 92,763,211NCBI
Celera1473,727,407 - 73,749,585 (+)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1473,853,819 - 73,875,859 (+)NCBIHuRef
CHM1_11493,611,452 - 93,633,593 (+)NCBICHM1_1
T2T-CHM13v2.01487,439,146 - 87,461,127 (+)NCBIT2T-CHM13v2.0
Ubr7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912102,724,234 - 102,743,960 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12102,724,226 - 102,743,966 (+)EnsemblGRCm39 Ensembl
GRCm3812102,757,975 - 102,777,701 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12102,757,967 - 102,777,707 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712103,996,185 - 104,015,911 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612103,159,025 - 103,178,751 (+)NCBIMGSCv36mm8
Celera12103,975,176 - 103,995,055 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1252.19NCBI
Ubr7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86127,663,454 - 127,683,302 (+)NCBIGRCr8
mRatBN7.26121,898,613 - 121,918,480 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6121,898,623 - 121,918,477 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6122,037,062 - 122,056,900 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06122,332,312 - 122,352,156 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06121,668,385 - 121,688,207 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06126,636,596 - 126,656,513 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6126,636,491 - 126,656,507 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06135,842,496 - 135,862,543 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46127,031,187 - 127,051,539 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16127,034,933 - 127,055,285 (+)NCBI
Celera6119,385,553 - 119,405,459 (+)NCBICelera
Cytogenetic Map6q32NCBI
Ubr7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543815,321,719 - 15,342,116 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543815,321,605 - 15,341,902 (+)NCBIChiLan1.0ChiLan1.0
UBR7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21594,364,758 - 94,386,911 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11493,581,263 - 93,603,416 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01473,839,702 - 73,861,830 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11493,176,149 - 93,198,156 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1493,176,149 - 93,198,150 (+)Ensemblpanpan1.1panPan2
UBR7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1862,410,589 - 62,426,436 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl862,410,640 - 62,435,677 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha861,987,543 - 62,003,406 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0862,681,294 - 62,697,384 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl862,681,319 - 62,707,820 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1862,360,209 - 62,376,067 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0862,411,591 - 62,427,462 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0862,741,076 - 62,756,952 (+)NCBIUU_Cfam_GSD_1.0
Ubr7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864012,319,842 - 12,339,891 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367331,127,145 - 1,147,210 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367331,127,150 - 1,147,192 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBR7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7114,590,945 - 114,609,858 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17114,590,920 - 114,609,867 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27121,176,292 - 121,195,060 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Ubr7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247349,630,964 - 9,652,428 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247349,630,810 - 9,651,395 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000009294   ⟹   ENSCSAP00000007418
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2470,945,629 - 70,969,594 (+)Ensembl
RefSeq Acc Id: XM_007987650   ⟹   XP_007985841
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12470,945,412 - 70,969,489 (+)NCBI
Vero_WHO_p1.0NW_02366605358,197,105 - 58,221,084 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007987651   ⟹   XP_007985842
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12470,945,634 - 70,969,489 (+)NCBI
Vero_WHO_p1.0NW_02366605358,197,276 - 58,221,084 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037984418   ⟹   XP_037840346
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605358,191,647 - 58,221,084 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007985841 (Get FASTA)   NCBI Sequence Viewer  
  XP_007985842 (Get FASTA)   NCBI Sequence Viewer  
  XP_037840346 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007418
  ENSCSAP00000007418.1
RefSeq Acc Id: XP_007985841   ⟸   XM_007987650
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RFM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007985842   ⟸   XM_007987651
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCSAP00000007418   ⟸   ENSCSAT00000009294
RefSeq Acc Id: XP_037840346   ⟸   XM_037984418
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011203 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009294.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro UBR7 UniProtKB/TrEMBL
  UBR7-like_UBR-box UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBR UniProtKB/TrEMBL
KEGG Report csab:103229585 UniProtKB/TrEMBL
NCBI Gene UBR7 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED UniProtKB/TrEMBL
  PTHR13513 UniProtKB/TrEMBL
Pfam zf-UBR UniProtKB/TrEMBL
PROSITE ZF_UBR UniProtKB/TrEMBL
SMART ZnF_UBR1 UniProtKB/TrEMBL
Superfamily-SCOP SSF57903 UniProtKB/TrEMBL
UniProt A0A0D9RFM9 ENTREZGENE, UniProtKB/TrEMBL