NAAA (N-acylethanolamine acid amidase)

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Gene: NAAA (N-acylethanolamine acid amidase) Chlorocebus sabaeus

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Symbol:

NAAA

Name:

N-acylethanolamine acid amidase

RGD ID:

18538945

Description:

ENCODES a protein that exhibits DNA-binding transcription factor binding (inferred); fatty acid amide hydrolase activity (inferred); hydrolase activity (inferred); INVOLVED IN fatty acid metabolic process (inferred); N-acylethanolamine metabolic process (inferred); N-acylphosphatidylethanolamine metabolic process (inferred); ASSOCIATED WITH progressive myoclonus epilepsy (ortholog); FOUND IN cytoplasm (inferred); lysosome (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

N-acylethanolamine-hydrolyzing acid amidase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	24,420,378 - 24,450,010 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	24,423,052 - 24,449,793 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	2,765,526 - 2,792,410 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

progressive myoclonus epilepsy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fatty acid metabolic process (IEA)

N-acylethanolamine metabolic process (IEA)

N-acylphosphatidylethanolamine metabolic process (IEA)

sphingosine metabolic process (IEA)

Cellular Component

cytoplasm (IEA)

lysosome (IEA)

membrane (IEA)

Molecular Function

DNA-binding transcription factor binding (IEA)

fatty acid amide hydrolase activity (IEA)

hydrolase activity (IEA)

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (IEA)

N-(long-chain-acyl)ethanolamine deacylase activity (IEA)

N-acylsphingosine amidohydrolase activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

NAAA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	24,420,378 - 24,450,010 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	24,423,052 - 24,449,793 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	2,765,526 - 2,792,410 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

NAAA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	75,910,655 - 75,941,013 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	75,910,655 - 75,941,013 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	76,831,808 - 76,862,166 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	77,050,832 - 77,081,190 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	77,195,814 - 77,219,325	NCBI
Celera	4	74,132,297 - 74,162,693 (-)	NCBI		Celera
Cytogenetic Map	4	q21.1	NCBI
HuRef	4	72,584,423 - 72,614,591 (-)	NCBI		HuRef
CHM1_1	4	76,808,474 - 76,838,830 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	79,251,154 - 79,281,501 (-)	NCBI		T2T-CHM13v2.0

Naaa
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	92,405,519 - 92,426,040 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	92,405,518 - 92,426,029 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	92,257,660 - 92,278,181 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	92,257,659 - 92,278,170 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	92,686,686 - 92,707,207 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	93,333,459 - 93,353,381 (-)	NCBI		MGSCv36	mm8
Celera	5	90,401,548 - 90,422,177 (-)	NCBI		Celera
Cytogenetic Map	5	E2	NCBI
cM Map	5	46.35	NCBI

Naaa
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	16,061,599 - 16,080,703 (+)	NCBI		GRCr8
mRatBN7.2	14	15,777,306 - 15,796,411 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	15,777,306 - 15,796,410 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	15,786,134 - 15,805,104 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	17,104,987 - 17,123,957 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	15,800,429 - 15,819,399 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	17,283,262 - 17,302,364 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	17,283,124 - 17,302,366 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	17,199,739 - 17,218,991 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	17,338,759 - 17,358,274 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	17,338,760 - 17,356,973 (+)	NCBI
Celera	14	15,171,712 - 15,190,788 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

Naaa
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955433	630,483 - 674,675 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955433	630,627 - 674,675 (-)	NCBI	ChiLan1.0	ChiLan1.0

NAAA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	54,131,808 - 54,162,106 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	54,321,585 - 54,351,911 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	48,264,567 - 48,294,872 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	54,102,384 - 54,133,725 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	54,102,384 - 54,128,776 (+)	Ensembl	panpan1.1		panPan2

NAAA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	483,317 - 504,304 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	41,379,385 - 41,398,991 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	507,696 - 527,349 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	32	507,868 - 527,523 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	460,034 - 485,704 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	39,688,753 - 39,708,408 (+)	NCBI		UU_Cfam_GSD_1.0

Naaa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	11,590,682 - 11,604,990 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936598	42,751 - 56,261 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NAAA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	71,573,788 - 71,603,338 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	71,573,783 - 71,603,256 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	75,709,382 - 75,738,808 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Naaa
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624757	15,074,189 - 15,099,876 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624757	15,074,137 - 15,101,342 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007998924	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007998926	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007998927	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007998928	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005237442	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000002704 ⟹ ENSCSAP00000000999

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	7	24,423,052 - 24,449,793 (-)	Ensembl

RefSeq Acc Id:

XM_007998924 ⟹ XP_007997115

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	7	24,423,046 - 24,450,010 (-)	NCBI
Vero_WHO_p1.0	NW_023666037	2,765,526 - 2,792,403 (-)	NCBI

Sequence:

show sequence

ATGCGCTGCGGGGACGGGAGGTGTCGCCTCTCCGGCTCGCCGGTGACAGGGGCGGGCGGGTCGT
GCGCGGGCCCCACCTCCAGCGGCCCCGCCCCAGGTCCTCCTCCTCCACGGCTTACCCGGGCTCC
GACAGCGGCTGCAGCTCTCCGAGTTGCGGCCGCAGGAGCCGGAGCCATGCGGACAGTAGACCCG
GAGGCGCGCCCGGGGCTTCTGCCCCTGCTGCTGCTGCTGCTGCTGGCCGAGGCCGGACTGTCCG
CCGCCTCACCCCCAGCAGCACCGCGCTTCAACGTGAGCCTGGATGCGGCCCCCGAGCTGCGCTG
GCTGCCAGTGCTGCGGCACTACGACTTGGACTTGGTGCGCGCAGCGATGGCGCAAGTCATCGGG
GATAGAGTCCCCAAGTGGGTGCACGTGTTGATCGGAAAAGTGGTCCTGGAGCTGGAGCGCTTCC
TGCCCCAGCCCTTCACCGGCGAGATCCGCGGCATGTGTGACTTCCTGAACCTCAGCCTGGCGGA
CTGCCTCCTGGTCAACCTGGCCTACGAGTCCTCCGCATTCTGCACCAGTATTGTGGCTCAAGAC
TCCAGAGGGCACATTTACCATGGTCGGAATCTGGATTATCCTTTTGGGAATGTCTTACGCAAGT
TGACCGTGGATGTGCAATTCTTAAAGAATGGGCAGATTGCATTCACAGGAACTACTTTTATTGG
CTATGTAGGATTATGGACTGGCCAGAGCCCACACAAGTTTACAGTTTCTGGTGATGAACGAGAT
AAAGGCTGGTGGTGGGAGAATGCTATCGCTGCCCTGTTTCAGAGACACATTCCGGTCAGCTGGC
TGATCCGCGCTACCCTGAATGAGTCAGAAAACTTCGAAGCAGCTGTTGGCAAGTTGGCCAAGAC
TCCCCTCATTGCTGATGTTTATTACATTGTTGGTGGCACCTCCCCCCAGGAGGGGGTGGTCATC
ACGAGGAACAGAGATGGCCCCGCAGACATTTGGCCTCTAGATCCTTTGAATGGAGTGTGGTTCC
GAGTTGAGACAAATTATGACCACTGGAAGCCAGCACCCAAGCGAGATGACCGGAGAACACCTGC
CATCAAGGCCCTTAATGCTACGGGACAAGCAAACCTCAGCCTGGAGGCACTTTTCCAGGTTTTG
TCGGTGGTTCCAGTTTGTAACAACCTCACAATTTATACTACGGTAATGAGCGCCGGTAGCCCAG
ACAAGTACATAAGTAGGATCAGAAACCCAAGTCGAAAGTAAGTCAGCAGAAGAGCGAGTTCATC
CGTGCTGTGAAAGATGATTTTTTAAAATGAAATTCTTGAAGAGCTGCACCTTAAAAAATCAGAG
AAAGTGAAAGTATTGTGTTATATTACGAACAATGCAGGCTCCTTCCTCATTTAACTTTTCAACC
TTGCGAAGTGGGGCCAGAAGTTTGATTTGGAGTTTGTGGTAAAGCCTGTAATGGGCATTGTCCT
GCACCCGCTTCCCTTCGTGGTTTGCCTCGATCCTCTCTAAGCTTACATCCTGGCCTGAATAACG
CAAAGATAATTGGTCTCAGAGTTCAAGCCATATCCTCAGACCTTATTTCCATCTTCTCATAAAT
CTGCCATCATACCTTTGCTTCTCCACTAATGAAATGAGCTGGCAAGACCTCTGTTCATTATGAA
GTGCTTCTGAAAGAGCCTAAAAAAAGGCTCATCTGAAAGAAATGGAGAGCTCTATTTCGAACCA
AGCCTGTTTGAATGTGTGTTAGTCTGATCTTTGATCATGTATTTCTATGTAATGGGAGTCTTGT
TTTTTATAATGTTTCTAATGTTTTATTGAAAAACCTATGGACCTCTTTCTTTCTCAACATCTAC
TTTCTTACTGCTTTTTGAAAATAATGTGCAACCAAATTGTTTCTTAATATCACATAATTAAGTA
ATAAAATGTCAAAAGAAATGTTGGCAAGAAGAATAAAAAAATTTTCCAAGAAATTTA

hide sequence

RefSeq Acc Id:

XR_005237442

Type:

NON-CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666037	2,765,526 - 2,792,410 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_007997115	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000000999.1

RefSeq Acc Id:	XP_007997115 ⟸ XM_007998924
- UniProtKB:	A0A0D9QXB0 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000000999 ⟸ ENSCSAT00000002704

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000004670	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000002704.1	UniProtKB/TrEMBL
InterPro	CBAH/NAAA_C	UniProtKB/TrEMBL
NCBI Gene	NAAA	ENTREZGENE
PANTHER	ACID AMIDASE	UniProtKB/TrEMBL
	N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE	UniProtKB/TrEMBL
Pfam	CBAH	UniProtKB/TrEMBL
UniProt	A0A0D9QXB0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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