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Gene: HERC4 (HECT and RLD domain containing E3 ubiquitin protein ligase 4) Chlorocebus sabaeus

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Symbol:

HERC4

Name:

HECT and RLD domain containing E3 ubiquitin protein ligase 4

RGD ID:

18522210

Description:

ENCODES a protein that exhibits ubiquitin-protein transferase activity (inferred); INVOLVED IN negative regulation of smoothened signaling pathway (inferred); spermatogenesis (inferred); ASSOCIATED WITH Autosomal Dominant Intellectual Developmental Disorder 70 (ortholog); FOUND IN cytosol (inferred); fibrillar center (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

probable E3 ubiquitin-protein ligase HERC4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	63,311,619 - 63,460,621 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	63,311,651 - 63,461,536 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	24,079,840 - 24,229,746 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Autosomal Dominant Intellectual Developmental Disorder 70 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of smoothened signaling pathway (IEA)

spermatogenesis (IEA)

Cellular Component

cytosol (IEA)

fibrillar center (IEA)

Molecular Function

ubiquitin-protein transferase activity (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

HERC4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	63,311,619 - 63,460,621 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	63,311,651 - 63,461,536 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	24,079,840 - 24,229,746 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

HERC4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	67,921,905 - 68,075,283 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	67,921,899 - 68,075,301 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	69,681,662 - 69,835,040 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	69,351,662 - 69,505,109 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	69,352,252 - 69,505,019	NCBI
Celera	10	62,956,525 - 63,109,715 (-)	NCBI		Celera
Cytogenetic Map	10	q21.3	NCBI
HuRef	10	63,681,241 - 63,834,644 (-)	NCBI		HuRef
CHM1_1	10	69,963,663 - 70,116,856 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	68,790,646 - 68,944,156 (-)	NCBI		T2T-CHM13v2.0

Herc4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	63,079,122 - 63,153,660 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	63,079,589 - 63,153,657 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	63,243,751 - 63,317,881 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	63,243,810 - 63,317,878 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	62,706,733 - 62,780,625 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	62,639,342 - 62,713,234 (+)	NCBI		MGSCv36	mm8
Celera	10	64,344,505 - 64,417,884 (+)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI
cM Map	10	32.56	NCBI

Herc4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	25,329,005 - 25,403,443 (-)	NCBI		GRCr8
mRatBN7.2	20	25,329,972 - 25,404,657 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	25,330,280 - 25,404,657 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	26,023,208 - 26,097,568 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	25,376,231 - 25,450,593 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	25,962,772 - 26,037,143 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	26,755,948 - 26,831,267 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	26,755,911 - 26,830,931 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	8,063,820 - 8,139,150 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	25,591,774 - 25,665,597 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	25,605,573 - 25,679,395 (+)	NCBI
Celera	20	26,628,361 - 26,702,717 (-)	NCBI		Celera
Cytogenetic Map	20	p11	NCBI

Herc4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	20,309,449 - 20,418,338 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	20,310,264 - 20,418,154 (-)	NCBI	ChiLan1.0	ChiLan1.0

HERC4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	80,084,224 - 80,238,793 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	80,090,126 - 80,244,093 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	64,405,164 - 64,559,651 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	66,717,537 - 66,870,774 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	66,716,761 - 66,870,774 (-)	Ensembl	panpan1.1		panPan2

HERC4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	19,223,525 - 19,352,490 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	19,210,166 - 19,351,709 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	19,352,188 - 19,484,809 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	19,489,565 - 19,622,141 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	19,489,565 - 19,622,026 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	19,372,156 - 19,504,936 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	19,594,124 - 19,726,917 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	19,937,349 - 20,070,205 (-)	NCBI		UU_Cfam_GSD_1.0

Herc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	61,683,669 - 61,800,939 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	10,176,132 - 10,292,845 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	10,176,191 - 10,294,761 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HERC4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	71,122,792 - 71,269,424 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	71,126,100 - 71,269,517 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	77,237,996 - 77,279,396 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Herc4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	2,336,163 - 2,466,862 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	2,335,585 - 2,466,955 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007963287	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007963288	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007963289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007963290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007963292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007963293	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007963294	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038009171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038009172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038009173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038009174	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000005564 ⟹ ENSCSAP00000003782

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	9	63,311,651 - 63,461,536 (+)	Ensembl

RefSeq Acc Id:

XM_007963290 ⟹ XP_007961481

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	9	63,311,619 - 63,460,621 (+)	NCBI
Vero_WHO_p1.0	NW_023666048	24,079,840 - 24,229,746 (+)	NCBI

Sequence:

show sequence

GCCAGCCCCTCCCCCGCCTCCCTCGCGTGGCCACCTCCCCCTCTGCCTTCTCCTACCCAGTCTC
TTTCCCCAACTCTCCCCACCCCTCGTGCTCTGCGCTCCGCTTGCCTCCTGTTCTTCCCCGCCCG
CTCCATCCGGGTCGCTGACGGCTGTCTCTGGACTGGACAGCAGTGGCGTCCGCTTTTCTCTAAG
GAACCCGATAAGAACTTCCATTTTCTGTTGATGTGGAGACATAGGGTACCTCCAACTTTCCGGG
GTTTCAGAAGAGAATTTTTTATTGAAACTGGAAGACCAAAATAATTACAAGCATGTTGTGCTGG
GGCAATGCATCCTTTGGACAGCTAGGTTTGGGTGGAATTGATGAAGAAATTGTACTAGAGCCCA
GAAAAAGTGACTTCTTTATAAATAAAAAGGTCCGAGATGTAGGATGTGGACTCAGACATACTGT
ATTTGTTCTGGATGATGGAACAGTGTACACTTGTGGATGTAATGATCTAGGACAGCTAGGTCAT
GAAAAATCCAGAAAGAAACCAGAGCAGGTTGTTGCCCTGGATGCCCAAAATATCGTAGCTGTTT
CATGTGGAGAAGCTCATACGTTAGCGCTAAATGACAAAGGCCAGGTGTATGCTTGGGGTCTCGA
TTCTGATGGACAGCTTGGCCTGCTAGGATCAGAGGAATGCATCAGAGTACCCAGAAATATTAAA
AGTTTGTCAGATATCCAGATTATACAGGTTGCTTGTGGTTACTATCATTCACTTGCACTTTCTA
AAGCAAGTGAAGTCTTCTGTTGGGGACAGAATAAATATGGCCAATTGGGTTTAGGTACTGACTG
TAAAAAGCAAACTTCACCACAGCTGATTAAGTCTTTGCTTGGAATCCCTTTCATGCAAGTTGCA
GCAGGAGGAGCCCATAGTTTTGTACTCACCCTTTCTGGAGCTATCTTTGGATGGGGACGCAACA
AGTTTGGTCAGCTAGGTCTTAATGATGAAAATGATAGGTATGTTCCTAATTTACTAAAGTCACT
AAGATCTCAGAAAATAGTTTATATTTGTTGTGGAGAAGATCATACTGCTGCACTAACCAAGGAA
GGTGGAGTGTTTACTTTTGGAGCTGGAGGGTATGGTCAGTTGGGCCATAATTCTACCAGTCATG
AAATAAACCCAAGGAAAGTTTTTGAACTTATGGGAAGCATTGTCACTCAGATTGCTTGTGGACG
GCAGCACACTTCTGCTTTTGTTCCTTCATCAGGACGAATTTACTCTTTTGGGCTTGGTGGTAAT
GGGCAGCTGGGAACCGGTTCAACAAGCAACAGAAAAAGTCCCTTTACTGTAAAAGGAAATTGGT
ACCCTTATAATGGGCAATGTCTACCAGATACTGATTCTGAAGAATATTTCTGTGTGAAAAGAAT
TTTCTCAGGGGGAGATCAAAGCTTTTCACATTACTCTAATCCCCAGAACTGTGGGCCACCAGAT
GACTTCAGATGTCCCGATCCTACAAAGCAGATCTGGACAGTGAATGAAGTTCTAATTCAGAAAT
GGCTGAGCTATCCTTCTGGAAGGTTTCCTGTGGAGATAGCCAATGAGATAGATGGAACATTTTC
TTCCTCTGGTTGCCTAAATGGAAGTTTTTTAGCTGTTAGCAATGATGATCACTATAGAACAGGT
ACCAGATTTTCAGGGGTTGATATGAATGCTGCTAGGCTTTTATTCCACAAACTTATACAACCTG
ATCATCCGCAGATATCTCAGCAGGTGGCAGCTAGTTTGGAAAAGAATCTTATTCCTAAACTGAC
TAGCTCCTTACCTGATGTTGAAGCATTGAGGTTTTATCTTACTCTACCAGAATGTCCCCTGATG
AGTGATTCCAACAATTTTACAACAATAGCAATTCCCTTTGGTACAGCTCTTGTGAACCTAGAAA
AGGCACCACTGAAAGTACTTGAAAACTGGTGGTCAGTACTTGAACCTCCACTGTTCCTCAAGAT
AGTAGAACTTTTTAAGGAAGTTGTGGTACATCTTTTGAAACTCTACAAGATCGGTATTCCCCCT
TCTGAAAGAAGAATTTTCAACAGTTTTCTTCATACTGCATTAAAGGTTTTAGAAATACTGCATA
GGGTAAATGAGAAAACGGGACAGATTATACAGTATGATAAATTTTATATACATGAAGTACAAGA
ATTGATAGACATAAGGAATGATTATATCAACTGGGTCCAACAACAGGCCTATGGAATGGATGTC
AACCATGGATTAACTGAGTTGGCAGATATCCCTGTTACAATCTGTACATATCCATTTGTATTTG
ATGCCCAAGCAAAAACTACTCTGTTACAGACTGATGCAGTCTTACAGATGCAGATGGCTATTGA
TCAGGCCCACAGGCAGAACGTCTCCTCTCTTTTTCTCCCAGTGATTGAATCTGTGAATCCCTGC
CTAATTCTAGTGGTGCGTAGAGAAAATATTGTAGGAGATGCAATGGAAGTCCTTAGGAAAACAA
AGAACATAGATTACAAGAAGCCACTCAAGGTTATATTTGTTGGAGAAGATGCTGTGGATGCAGG
AGGGGTGCGCAAAGAATTTTTCTTGCTCATCATGAGGGAATTATTGGATCCTAAGTATGGCATG
TTTAGGTATTATGAAGATTCCAGGCTCATTTGGTTTTCTGATAAGACGTTTGAAGACAGTGATT
TGTTCCATTTGATTGGTGTTATCTGTGGCTTAGCAATTTATAATTTTACTATTGTGGACCTCCA
TTTTCCTTTGGCTTTATATAAGAAACTACTGAAAAAGAAGCCATCCTTGGATGATTTGAAAGAA
CTAATGCCTGATGTTGGGAGAAGCATGCAACAGTTACTGGATTATCCAGAAGATGACATAGAGG
AAACATTTTGTCTTAATTTTACGATCACAGTTGAAAACTTTGGTGCAACAGAAGTCAAAGAGCT
GGTTCTAAATGGTGCAGACACAGCTGTTAACAAACAAAATCGACAAGAGTTTGTTGATGCTTAT
GTGGATTACATATTCAATAAATCAGTGGCTTCCTTATTTGATGCTTTTCATGCGGGCTTTCATA
AGGTCTGTGGAGGAAAAGTCCTTCTGCTCTTTCAGCCTAATGAACTACAAGCAATGGTCATTGG
AAATACAAATTATGATTGGAAGGAACTGGAAAAGAATACAGAATACAAAGGGGAATATTGGGCA
GAACATCCTACGATAAAAATTTTTTGGGAAGTATTTCACGAATTACCATTGGAAAAGAAGAAGC
AGTTTCTGTTATTTTTGACAGGTAGTGATCGCATTCCTATTCTTGGTATGAAGAGTCTGAAACT
AGTCATCCAGTCAACAGGAGGTGGTGAGGAATATCTCCCAGTTTCCCATACTTGTTTTAATCTT
CTGGATCTTCCAAAATATACAGATAAAGAAACTCTACGCTCTAAACTGATCCAAGCTATTGATC
ACAATGAAGGCTTCAGTTTAATATAACTTTGGAGTTCAACTATTCAGTTTAGTGCAAAAGCATT
AAACTATTTGTGTTTTTCTTGTGGTGATGAATTCAGCAAGGTGACAGAGGTACTATTATAATTC
TTACTTGCAGAATGTTCAATCTACGAGTGTTCATGGAAGTCAAAACATTAAAGGAAAATGAACA
AACTGTTAATATTATTGTACAGAACCATGGATTTTTTTGACCATCTTCCAATAAACATAACAAG
TATTGTGAATACATTAAAGTTCTACTAACATGAGTTTTAAGAGTTTGCATATTTCAGAAATGAT
CTGGTGTGAGTGCATGGAAATATTGCTTAATTTTTCTTCAATCATTGAGTGAAAAACCTTTAAC
TTTGGCCTGCAATAGTCATTTCATTATTTTTTCATTTTGTAAATAATGTTAAGTTTTGTAATAA
AATAGTTATGTTCTGATACCAGTA

hide sequence

RefSeq Acc Id:

XM_007963292 ⟹ XP_007961483

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	9	63,311,619 - 63,460,618 (+)	NCBI
Vero_WHO_p1.0	NW_023666048	24,079,840 - 24,229,746 (+)	NCBI

Sequence:

show sequence

GCCAGCCCCTCCCCCGCCTCCCTCGCGTGGCCACCTCCCCCTCTGCCTTCTCCTACCCAGTCTC
TTTCCCCAACTCTCCCCACCCCTCGTGCTCTGCGCTCCGCTTGCCTCCTGTTCTTCCCCGCCCG
CTCCATCCGGGTCGCTGACGGCTGTCTCTGGACTGGACAGCAGTGGCGTCCGCTTTTCTCTAAG
GAACCCGATAAGAACTTCCATTTTCTGTTGATGTGGAGACATAGGGTACCTCCAACTTTCCGGG
GTTTCAGAAGAGAATTTTTTATTGAAACTGGAAGACCAAAATAATTACAAGCATGTTGTGCTGG
GGCAATGCATCCTTTGGACAGCTAGGTTTGGGTGGAATTGATGAAGAAATTGTACTAGAGCCCA
GAAAAAGTGACTTCTTTATAAATAAAAAGGTCCGAGATGTAGGATGTGGACTCAGACATACTGT
ATTTGTTCTGGATGATGGAACAGTGTACACTTGTGGATGTAATGATCTAGGACAGCTAGGTCAT
GAAAAATCCAGAAAGAAACCAGAGCAGGTTGTTGCCCTGGATGCCCAAAATATCGTAGCTGTTT
CATGTGGAGAAGCTCATACGTTAGCGCTAAATGACAAAGGCCAGGTGTATGCTTGGGGTCTCGA
TTCTGATGGACAGCTTGGCCTGCTAGGATCAGAGGAATGCATCAGAGTACCCAGAAATATTAAA
AGTTTGTCAGATATCCAGATTATACAGGTTGCTTGTGGTTACTATCATTCACTTGCACTTTCTA
AAGCAAGTGAAGTCTTCTGTTGGGGACAGAATAAATATGGCCAATTGGGTTTAGGTACTGACTG
TAAAAAGCAAACTTCACCACAGCTGATTAAGTCTTTGCTTGGAATCCCTTTCATGCAAGTTGCA
GCAGGAGGAGCCCATAGTTTTGTACTCACCCTTTCTGGAGCTATCTTTGGATGGGGACGCAACA
AGTTTGGTCAGCTAGGTCTTAATGATGAAAATGATAGGTATGTTCCTAATTTACTAAAGTCACT
AAGATCTCAGAAAATAGTTTATATTTGTTGTGGAGAAGATCATACTGCTGCACTAACCAAGGAA
GGTGGAGTGTTTACTTTTGGAGCTGGAGGGTATGGTCAGTTGGGCCATAATTCTACCAGTCATG
AAATAAACCCAAGGAAAGTTTTTGAACTTATGGGAAGCATTGTCACTCAGATTGCTTGTGGACG
GCAGCACACTTCTGCTTTTGTTCCTTCATCAGGACGAATTTACTCTTTTGGGCTTGGTGGTAAT
GGGCAGCTGGGAACCGGTTCAACAAGCAACAGAAAAAGTCCCTTTACTGTAAAAGGAAATTGGT
ACCCTTATAATGGGCAATGTCTACCAGATACTGATTCTGAAGAATATTTCTGTGTGAAAAGAAT
TTTCTCAGGGGGAGATCAAAGCTTTTCACATTACTCTAATCCCCAGAACTGTGGGCCACCAGAT
GACTTCAGATGTCCCGATCCTACAAAGCAGATCTGGACAGTGAATGAAGTTCTAATTCAGAAAT
GGCTGAGCTATCCTTCTGGAAGGTTTCCTGTGGAGATAGCCAATGAGATAGATGGAACATTTTC
TTCCTCTGGTTGCCTAAATGGAAGTTTTTTAGCTGTTAGCAATGATGATCACTATAGAACAGGT
ACCAGATTTTCAGGGGTTGATATGAATGCTGCTAGGCTTTTATTCCACAAACTTATACAACCTG
ATCATCCGCAGATATCTCAGCAGGTGGCAGCTAGTTTGGAAAAGAATCTTATTCCTAAACTGAC
TAGCTCCTTACCTGATGTTGAAGCATTGAGGTTTTATCTTACTCTACCAGAATGTCCCCTGATG
AGTGATTCCAACAATTTTACAACAATAGCAATTCCCTTTGGTACAGCTCTTGTGAACCTAGAAA
AGGCACCACTGAAAGTACTTGAAAACTGGTGGTCAGTACTTGAACCTCCACTGTTCCTCAAGAT
AGTAGAACTTTTTAAGGAAGTTGTGGTACATCTTTTGAAACTCTACAAGATCGGTATTCCCCCT
TCTGAAAGAAGAATTTTCAACAGTTTTCTTCATACTGCATTAAAGGTTTTAGAAATACTGCATA
GGGTAAATGAGAAAACGGGACAGATTATACAGTATGATAAATTTTATATACATGAAGTACAAGA
ATTGATAGACATAAGGAATGATTATATCAACTGGGTCCAACAACAGGCCTATGGAATGTTGGCA
GATATCCCTGTTACAATCTGTACATATCCATTTGTATTTGATGCCCAAGCAAAAACTACTCTGT
TACAGACTGATGCAGTCTTACAGATGCAGATGGCTATTGATCAGGCCCACAGGCAGAACGTCTC
CTCTCTTTTTCTCCCAGTGATTGAATCTGTGAATCCCTGCCTAATTCTAGTGGTGCGTAGAGAA
AATATTGTAGGAGATGCAATGGAAGTCCTTAGGAAAACAAAGAACATAGATTACAAGAAGCCAC
TCAAGGTTATATTTGTTGGAGAAGATGCTGTGGATGCAGGAGGGGTGCGCAAAGAATTTTTCTT
GCTCATCATGAGGGAATTATTGGATCCTAAGTATGGCATGTTTAGGTATTATGAAGATTCCAGG
CTCATTTGGTTTTCTGATAAGACGTTTGAAGACAGTGATTTGTTCCATTTGATTGGTGTTATCT
GTGGCTTAGCAATTTATAATTTTACTATTGTGGACCTCCATTTTCCTTTGGCTTTATATAAGAA
ACTACTGAAAAAGAAGCCATCCTTGGATGATTTGAAAGAACTAATGCCTGATGTTGGGAGAAGC
ATGCAACAGTTACTGGATTATCCAGAAGATGACATAGAGGAAACATTTTGTCTTAATTTTACGA
TCACAGTTGAAAACTTTGGTGCAACAGAAGTCAAAGAGCTGGTTCTAAATGGTGCAGACACAGC
TGTTAACAAACAAAATCGACAAGAGTTTGTTGATGCTTATGTGGATTACATATTCAATAAATCA
GTGGCTTCCTTATTTGATGCTTTTCATGCGGGCTTTCATAAGGTCTGTGGAGGAAAAGTCCTTC
TGCTCTTTCAGCCTAATGAACTACAAGCAATGGTCATTGGAAATACAAATTATGATTGGAAGGA
ACTGGAAAAGAATACAGAATACAAAGGGGAATATTGGGCAGAACATCCTACGATAAAAATTTTT
TGGGAAGTATTTCACGAATTACCATTGGAAAAGAAGAAGCAGTTTCTGTTATTTTTGACAGGTA
GTGATCGCATTCCTATTCTTGGTATGAAGAGTCTGAAACTAGTCATCCAGTCAACAGGAGGTGG
TGAGGAATATCTCCCAGTTTCCCATACTTGTTTTAATCTTCTGGATCTTCCAAAATATACAGAT
AAAGAAACTCTACGCTCTAAACTGATCCAAGCTATTGATCACAATGAAGGCTTCAGTTTAATAT
AACTTTGGAGTTCAACTATTCAGTTTAGTGCAAAAGCATTAAACTATTTGTGTTTTTCTTGTGG
TGATGAATTCAGCAAGGTGACAGAGGTACTATTATAATTCTTACTTGCAGAATGTTCAATCTAC
GAGTGTTCATGGAAGTCAAAACATTAAAGGAAAATGAACAAACTGTTAATATTATTGTACAGAA
CCATGGATTTTTTTGACCATCTTCCAATAAACATAACAAGTATTGTGAATACATTAAAGTTCTA
CTAACATGAGTTTTAAGAGTTTGCATATTTCAGAAATGATCTGGTGTGAGTGCATGGAAATATT
GCTTAATTTTTCTTCAATCATTGAGTGAAAAACCTTTAACTTTGGCCTGCAATAGTCATTTCAT
TATTTTTTCATTTTGTAAATAATGTTAAGTTTTGTAATAAAATAGTTATGTTCTGATACCA

hide sequence

RefSeq Acc Id:

XM_038009171 ⟹ XP_037865099

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	24,080,049 - 24,229,746 (+)	NCBI

RefSeq Acc Id:

XM_038009172 ⟹ XP_037865100

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	24,080,359 - 24,229,746 (+)	NCBI

RefSeq Acc Id:

XM_038009173 ⟹ XP_037865101

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	24,080,055 - 24,229,746 (+)	NCBI

RefSeq Acc Id:

XM_038009174 ⟹ XP_037865102

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	24,079,859 - 24,229,746 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_007961481	(Get FASTA)	NCBI Sequence Viewer
	XP_007961483	(Get FASTA)	NCBI Sequence Viewer
	XP_037865099	(Get FASTA)	NCBI Sequence Viewer
	XP_037865100	(Get FASTA)	NCBI Sequence Viewer
	XP_037865101	(Get FASTA)	NCBI Sequence Viewer
	XP_037865102	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000003782
	ENSCSAP00000003782.1

RefSeq Acc Id:	XP_007961481 ⟸ XM_007963290
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9R593 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007961483 ⟸ XM_007963292
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSCSAP00000003782 ⟸ ENSCSAT00000005564

RefSeq Acc Id:	XP_037865102 ⟸ XM_038009174
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_037865099 ⟸ XM_038009171
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9R593 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037865101 ⟸ XM_038009173
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9R593 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037865100 ⟸ XM_038009172
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9R593 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000007517	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000005564.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.30	UniProtKB/TrEMBL
	Hect, E3 ligase catalytic domain	UniProtKB/TrEMBL
	Hect, E3 ligase catalytic domain	UniProtKB/TrEMBL
	Hect, E3 ligase catalytic domains	UniProtKB/TrEMBL
InterPro	HECT_dom	UniProtKB/TrEMBL
	Hect_E3_ubiquitin_ligase	UniProtKB/TrEMBL
	RCC1/BLIP-II	UniProtKB/TrEMBL
	Reg_chr_condens	UniProtKB/TrEMBL
	Ub_ligase/GEF_domain	UniProtKB/TrEMBL
NCBI Gene	HERC4	ENTREZGENE
PANTHER	BTB DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	REGULATOR OF CHROMOSOME CONDENSATION	UniProtKB/TrEMBL
Pfam	HECT	UniProtKB/TrEMBL
	RCC1	UniProtKB/TrEMBL
PRINTS	RCCNDNSATION	UniProtKB/TrEMBL
PROSITE	HECT	UniProtKB/TrEMBL
	RCC1_2	UniProtKB/TrEMBL
	RCC1_3	UniProtKB/TrEMBL
SMART	HECTc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50985	UniProtKB/TrEMBL
	SSF56204	UniProtKB/TrEMBL
UniProt	A0A0D9R593	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar