Sult6b1 (sulfotransferase family, cytosolic, 6B, member 1) - Rat Genome Database

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Gene: Sult6b1 (sulfotransferase family, cytosolic, 6B, member 1) Mus musculus
Analyze
Symbol: Sult6b1
Name: sulfotransferase family, cytosolic, 6B, member 1
RGD ID: 1617484
MGI Page MGI
Description: Predicted to enable sulfotransferase activity. Predicted to be involved in sulfation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human SULT6B1 (sulfotransferase family 6B member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2410078J06Rik; AV101767; ST6B1; sulfotransferase 6B1; Thyroxine sulfotransferase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391779,192,314 - 79,214,421 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1779,191,367 - 79,214,421 (-)EnsemblGRCm39 Ensembl
GRCm381778,884,885 - 78,906,992 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,883,938 - 78,906,992 (-)EnsemblGRCm38mm10GRCm38
MGSCv371779,283,278 - 79,306,332 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361778,789,954 - 78,812,050 (-)NCBIMGSCv36mm8
Celera1783,202,249 - 83,225,316 (-)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1749.6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
RASopathy  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
sulfation  (IBA)

Cellular Component
cytoplasm  (IBA)
cytosol  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:14610273   PMID:16141072   PMID:16141073   PMID:17062627   PMID:18799693   PMID:19468303   PMID:19505954  
PMID:21677750   PMID:21873635  


Genomics

Comparative Map Data
Sult6b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391779,192,314 - 79,214,421 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1779,191,367 - 79,214,421 (-)EnsemblGRCm39 Ensembl
GRCm381778,884,885 - 78,906,992 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,883,938 - 78,906,992 (-)EnsemblGRCm38mm10GRCm38
MGSCv371779,283,278 - 79,306,332 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361778,789,954 - 78,812,050 (-)NCBIMGSCv36mm8
Celera1783,202,249 - 83,225,316 (-)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1749.6NCBI
SULT6B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38237,167,820 - 37,196,087 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl237,167,820 - 37,196,598 (-)EnsemblGRCh38hg38GRCh38
GRCh37237,394,963 - 37,423,230 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36237,248,467 - 37,269,194 (-)NCBINCBI36Build 36hg18NCBI36
Celera237,235,972 - 37,256,698 (-)NCBICelera
Cytogenetic Map2p22.2NCBI
HuRef237,134,927 - 37,155,656 (-)NCBIHuRef
CHM1_1237,324,264 - 37,345,036 (-)NCBICHM1_1
T2T-CHM13v2.0237,174,929 - 37,203,178 (-)NCBIT2T-CHM13v2.0
Sult6b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8621,914,535 - 21,939,264 (+)NCBIGRCr8
mRatBN7.2616,162,382 - 16,187,116 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,162,150 - 16,187,116 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx616,477,674 - 16,502,616 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0616,799,884 - 16,824,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,281,151 - 16,305,883 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.061,468,083 - 1,493,670 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl61,468,083 - 1,493,670 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.061,458,526 - 1,484,401 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera615,827,201 - 15,849,554 (+)NCBICelera
Cytogenetic Map6q12NCBI
Sult6b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554414,971,283 - 4,994,219 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554414,971,283 - 4,994,219 (-)NCBIChiLan1.0ChiLan1.0
SULT6B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21289,281,777 - 89,316,470 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A89,285,753 - 89,316,057 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A37,194,931 - 37,224,700 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A37,959,377 - 37,989,621 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A37,959,377 - 37,980,695 (-)Ensemblpanpan1.1panPan2
SULT6B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11729,536,943 - 29,556,092 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1729,537,940 - 29,555,961 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01730,187,521 - 30,205,593 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1730,187,555 - 30,205,654 (-)EnsemblROS_Cfam_1.0 Ensembl
Sult6b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629242,429,010 - 42,447,905 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366631,094,532 - 1,113,261 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366631,094,532 - 1,113,261 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SULT6B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3103,012,000 - 103,034,140 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13103,011,043 - 103,034,818 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SULT6B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11470,204,427 - 70,227,680 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1470,205,121 - 70,226,977 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604541,723,015 - 41,753,815 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sult6b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473818,784,239 - 18,808,370 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473818,783,413 - 18,808,941 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sult6b1
985 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:732
Count of miRNA genes:433
Interacting mature miRNAs:500
Transcripts:ENSMUST00000042683, ENSMUST00000146474, ENSMUST00000159710, ENSMUST00000169544
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141758Pstc5_mperiosteal circumference 5 (mouse)Not determined175710765191107803Mouse
4142201Obrq15_mobesity resistance QTL 15 (mouse)Not determined5753444780885776Mouse
4141879Chlq9_mcirculating hormone level QTL 9 (mouse)Not determined175175842585758612Mouse
1357532Bmch7_mbone mechanical trait 7 (mouse)Not determined175175842585758612Mouse
11528551Sluc32_msusceptibility to lung cancer 32 (mouse)176230101095294699Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
12910536Nrq8a_mnoise-induced hearing loss resistant QTL 8a (mouse)175710765191107803Mouse
1357528Nhdlq3_mnon-HDL QTL 3 (mouse)Not determined177339513295294699Mouse
12910537Nrq8_mnoise-induced hearing loss resistant QTL 8 (mouse)175710765191107803Mouse
4141040Hmtb9_mhemostasis and thrombosis rebleeding time 9 (mouse)Not determined5758908991589197Mouse
4142256Nilac12_mnicotine induced locomotor activity 12 (mouse)Not determined176894131995294699Mouse
1302017Aliq3_macute lung injury QTL 3 (mouse)Not determined176388554895294699Mouse
1357447Heal13_mwound healing/regeneration 13 (mouse)Not determined175710765191107803Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174651092682407429Mouse
14928308Manh82_mmandible shape 82 (mouse)176631524395294699Mouse
1357646Axtq3_manxiety QTL 3 (mouse)Not determined177458908990395270Mouse
1301107Scc4_mcolon tumor susceptibility 4 (mouse)Not determined176230101095294699Mouse
11039498Ltpr7b_mLeishmania tropica response 7b (mouse)177070119895294699Mouse
11039499Ltpr7a_mLeishmania tropica response 7a (mouse)177070119895294699Mouse
11039500Ltpr7c_mLeishmania tropica response 7c (mouse)177070119895294699Mouse
1357552Aaj4_manxiety in A/J 4 (mouse)Not determined177458908990395270Mouse
4141011Bmd26_mbone mineral density 26 (mouse)Not determined175710765191107803Mouse
1300735Pgia20_mproteoglycan induced arthritis 20 (mouse)Not determined175710765191107803Mouse
1357754Ahl3_mage related hearing loss 3 (mouse)Not determined175020395784204103Mouse
4142414Pregq4_mpregnancy QTL 4 (mouse)Not determined175753444793507179Mouse
11039514Ltpr7_mLeishmania tropica response 7 (mouse)177070119895294699Mouse
1301728Ffal1_mfree fatty acid level 1 (mouse)Not determined176521493895294699Mouse
13464254Ifvrq3_minfluenza virus resistance QTL 3 (mouse)176795765583908089Mouse
4141195Nilac11_mnicotine induced locomotor activity 11 (mouse)Not determined177339513295294699Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
4141697Hbnr3_mHeligmosomoides bakeri nematode resistance 3 (mouse)Not determined7410765193507179Mouse

Markers in Region
AV101767  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381778,885,080 - 78,885,191UniSTSGRCm38
MGSCv371779,284,420 - 79,284,531UniSTSGRCm37
Celera1799,826,251 - 99,826,362UniSTS
Celera1783,203,388 - 83,203,499UniSTS
Cytogenetic Map17E3UniSTS
Whitehead/MRC_RH17934.45UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000042683   ⟹   ENSMUSP00000038282
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1779,192,495 - 79,214,328 (-)Ensembl
GRCm38.p6 Ensembl1778,885,066 - 78,906,899 (-)Ensembl
Ensembl Acc Id: ENSMUST00000146474
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1779,192,326 - 79,202,529 (-)Ensembl
GRCm38.p6 Ensembl1778,884,897 - 78,895,100 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159710   ⟹   ENSMUSP00000124309
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1779,192,495 - 79,214,328 (-)Ensembl
GRCm38.p6 Ensembl1778,885,066 - 78,906,899 (-)Ensembl
Ensembl Acc Id: ENSMUST00000169544   ⟹   ENSMUSP00000132823
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1779,191,367 - 79,214,421 (-)Ensembl
GRCm38.p6 Ensembl1778,883,938 - 78,906,992 (-)Ensembl
RefSeq Acc Id: NM_001163625   ⟹   NP_001157097
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391779,192,316 - 79,214,421 (-)NCBI
GRCm381778,884,887 - 78,906,992 (-)NCBI
MGSCv371779,283,278 - 79,306,332 (-)RGD
Celera1783,202,249 - 83,225,316 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011246656   ⟹   XP_011244958
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391779,192,314 - 79,212,435 (-)NCBI
GRCm381778,884,885 - 78,905,006 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001157097 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244958 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000038282
  ENSMUSP00000038282.7
  ENSMUSP00000124309.2
  ENSMUSP00000132823.2
GenBank Protein P0CC03 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001157097   ⟸   NM_001163625
- UniProtKB: P0CC03 (UniProtKB/Swiss-Prot),   E9QNJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244958   ⟸   XM_011246656
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000124309   ⟸   ENSMUST00000159710
Ensembl Acc Id: ENSMUSP00000038282   ⟸   ENSMUST00000042683
Ensembl Acc Id: ENSMUSP00000132823   ⟸   ENSMUST00000169544
Protein Domains
Sulfotransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0CC03-F1-model_v2 AlphaFold P0CC03 1-303 view protein structure

Promoters
RGD ID:13676804
Promoter ID:EPDNEW_M22551
Type:initiation region
Name:Sult6b1_1
Description:Mus musculus sulfotransferase family, cytosolic, 6B, member 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381778,895,099 - 78,895,159EPDNEW
RGD ID:6828734
Promoter ID:MM_KWN:24237
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:OTTMUST00000082375
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361779,294,126 - 79,294,626 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1920921 AgrOrtholog
Ensembl Genes ENSMUSG00000038045 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000042683 ENTREZGENE
  ENSMUST00000042683.7 UniProtKB/TrEMBL
  ENSMUST00000159710.2 UniProtKB/TrEMBL
  ENSMUST00000169544.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:73671 UniProtKB/Swiss-Prot
MGD MGI:1920921 ENTREZGENE
NCBI Gene 73671 ENTREZGENE
PANTHER SULFOTRANSFERASE 6B1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SULFOTRANSFERASE SULT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sult6b1 PhenoGen
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E0CYC7_MOUSE UniProtKB/TrEMBL
  E9QNJ5 ENTREZGENE, UniProtKB/TrEMBL
  P0CC03 ENTREZGENE, UniProtKB/Swiss-Prot