Ube2frt (ubiquitin-conjugating enzyme E2F (putative), retrotransposed) - Rat Genome Database

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Gene: Ube2frt (ubiquitin-conjugating enzyme E2F (putative), retrotransposed) Mus musculus
Analyze
No known orthologs.
Symbol: Ube2frt
Name: ubiquitin-conjugating enzyme E2F (putative), retrotransposed
RGD ID: 1615475
MGI Page MGI
Description: Predicted to enable NEDD8 conjugating enzyme activity. Predicted to be involved in protein neddylation. Predicted to be active in cytosol and nucleus. Orthologous to human UBE2F (ubiquitin conjugating enzyme E2 F (putative)).
Type: pseudo (Ensembl: transcribed_processed_pseudogene)
RefSeq Status: VALIDATED
Previously known as: EG432649; Gm5434
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: Ube2f  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391236,140,378 - 36,141,828 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1236,140,378 - 36,141,828 (+)EnsemblGRCm39 Ensembl
GRCm381236,090,379 - 36,091,829 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1236,090,379 - 36,091,829 (+)EnsemblGRCm38mm10GRCm38
MGSCv371236,816,966 - 36,818,416 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361236,600,649 - 36,602,051 (+)NCBIMGSCv36mm8
Celera1237,544,363 - 37,545,813 (+)NCBICelera
Cytogenetic Map12A3NCBI
cM Map1216.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
protein neddylation  (IBA,IEA,ISO,ISS)

Cellular Component
cytosol  (IBA)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21677750   PMID:21873635  


Genomics

Variants

.
Variants in Ube2frt
63 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:230
Count of miRNA genes:199
Interacting mature miRNAs:207
Transcripts:ENSMUST00000071825
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300818Bbaa10_mB.burgdorferi-associated arthritis 10 (mouse)Not determined123509100465511019Mouse
1301723Fcsa7_mfemoral cross-sectional area 7 (mouse)Not determined12949100443491112Mouse
4142002Tbqt3_mtibia bone quality traits 3 (mouse)Not determined1235285496109936243Mouse
15039339Nmrs29_mNAFLD-associated magnetic resonance shift 29 (mouse)121782585251825852Mouse
1302172Skts5_mskin tumor susceptibility 5 (mouse)Not determined122214886656149016Mouse
1300636Gct2_mgranulosa cell tumorigenesis 2 (mouse)Not determined122916068563160884Mouse
10043977Obq34_mobesity QTL 34 (mouse)Not determined121514733149147331Mouse
10043848Hdlq90_mHDL QTL 90 (mouse)Not determined121783993951840081Mouse
14696690Rfq1_mrearing frequency QTL 1, males (mouse)123604999937049999Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
1301574Lmblgq5_mlimb length QTL 5 (mouse)Not determined121759644780956883Mouse
1300870Ath18_matherosclerosis 18 (mouse)Not determined121825996652260067Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
14747008Mancz10_mmandible centroid size 10 (mouse)122986352263863522Mouse
10402492Dipa8_mdrug induced psychomotor activation 8 (mouse)Not determined123493387268934019Mouse
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
13524843Ppiq8_mprepulse inhibition QTL 8 (mouse)121104319450945796Mouse
26884413Bzwq9_mbi-zygomatic width QTL 9, 10 week (mouse)121615000147746783Mouse
13524839Ppiq10_mprepulse inhibition QTL 10 (mouse)121304319554945798Mouse
4141843Moen3_mmodifier of engrailed QTL 3 (mouse)Not determined122980158463801733Mouse
13208568Bmiq11_mbody mass index QTL 11 (mouse)12805000040049999Mouse
4141516slwr_mslowlearner (mouse)Not determined1239247546392614Mouse
1301989Hdlq18_mHDL QTL 18 (mouse)Not determined122916068563160884Mouse
1301163Eae16_msusceptibility to experimental allergic encephalomyelitis 16 (mouse)Not determined12772315841723301Mouse
12904956Edlmmq10_mextensor digitorum longus muscle mass QTL 10 (mouse)121973983353739833Mouse
14746972Manh72_mmandible shape 72 (mouse)121061528144615281Mouse
1301037Cd4ts5_mCD4 T cell subset 5 (mouse)Not determined12835244442352581Mouse
10401249Bglu15_mblood glucose level 15 (mouse)Not determined121062064244620809Mouse
12879483Asp1_maudiogenic seizure prone 1 (mouse)123528549646801733Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000071825
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1236,140,378 - 36,141,828 (+)Ensembl
GRCm38.p6 Ensembl1236,090,379 - 36,091,829 (+)Ensembl
RefSeq Acc Id: NR_003649
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391236,140,378 - 36,141,828 (+)NCBI
GRCm381236,090,379 - 36,091,829 (+)ENTREZGENE
MGSCv371236,816,966 - 36,818,416 (+)RGD
Celera1237,544,363 - 37,545,813 (+)RGD
cM Map12 ENTREZGENE
Sequence:
Protein Sequences
GenBank Protein BAE22861 (Get FASTA)   NCBI Sequence Viewer  
  Q3UWQ3 (Get FASTA)   NCBI Sequence Viewer  
Protein Domains
UBC core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3UWQ3-F1-model_v2 AlphaFold Q3UWQ3 1-185 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3646221 AgrOrtholog
Ensembl Genes ENSMUSG00000059301 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000071825 ENTREZGENE
Gene3D-CATH 3.10.110.10 UniProtKB/Swiss-Prot
InterPro Ub_conjugating_enzyme UniProtKB/Swiss-Prot
  UBQ-conjugat_E2 UniProtKB/Swiss-Prot
  UBQ-conjugating_AS UniProtKB/Swiss-Prot
  UBQ-conjugating_enzyme/RWD UniProtKB/Swiss-Prot
MGD MGI:3646221 ENTREZGENE
NCBI Gene 432649 ENTREZGENE
PANTHER NEDD8-CONJUGATING ENZYME UBC-12 UniProtKB/Swiss-Prot
  UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/Swiss-Prot
Pfam UQ_con UniProtKB/Swiss-Prot
PhenoGen Ube2frt PhenoGen
PROSITE UBIQUITIN_CONJUGAT_1 UniProtKB/Swiss-Prot
  UBIQUITIN_CONJUGAT_2 UniProtKB/Swiss-Prot
SMART UBCc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54495 UniProtKB/Swiss-Prot
UniProt Q3UWQ3 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-21 Ube2frt  ubiquitin-conjugating enzyme E2F (putative), retrotransposed  Gm5434  predicted gene 5434  Symbol and/or name updated 27372883 PROVISIONAL