H2-Q9 (histocompatibility 2, Q region locus 9) - Rat Genome Database

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Gene: H2-Q9 (histocompatibility 2, Q region locus 9) Mus musculus
Analyze
No known orthologs.
Symbol: H2-Q9
Name: histocompatibility 2, Q region locus 9
RGD ID: 1613285
MGI Page MGI
Description: Enables peptide antigen binding activity. Acts upstream of or within several processes, including defense response to symbiont; positive regulation of T cell mediated cytotoxicity; and positive regulation of type II interferon production. Located in external side of plasma membrane. Part of MHC class Ib protein complex. Is expressed in early conceptus; inner cell mass; and spleen.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: H-2 class I histocompatibility antigen, Q9 alpha chain; H-2Q9; MGC155791; Pe; Ped; Qa; Qa-; Qa-2; Qa-9; Qa9
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,752,074 - 35,756,659 (+)NCBIGRCm39GRCm39mm39
MGSCv371735,576,106 - 35,580,716 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Cytogenetic Map17B1NCBI
cM Map1719.21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2767053   PMID:3004940   PMID:3025084   PMID:3356450   PMID:3701254   PMID:6088985   PMID:6193187   PMID:6280871   PMID:6399516   PMID:7819451   PMID:8833240   PMID:8952959  
PMID:9604770   PMID:9746747   PMID:9809678   PMID:10208972   PMID:12389096   PMID:12466851   PMID:12477932   PMID:12707328   PMID:14691545   PMID:15383569   PMID:15747579   PMID:16887971  
PMID:18416856   PMID:18541714   PMID:21873635   PMID:22001201   PMID:27113764  


Genomics

Variants

.
Variants in H2-Q9
3 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1302189Dps3_mdelta power in slow-wave sleep 3 (mouse)Not determined173381972136250180Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173206165237644775Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse

Markers in Region
H2-Q7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371735,576,394 - 35,577,095UniSTSGRCm37
Cytogenetic Map17B1UniSTS
cM Map1719.21UniSTS
cM Map1719.2UniSTS
cM Map1719.19UniSTS
H2-Q7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,439,449 - 35,440,150UniSTSGRCm38
MGSCv371735,576,394 - 35,577,095UniSTSGRCm37
Cytogenetic Map17B1UniSTS


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: NM_001201460   ⟹   NP_001188389
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391735,752,074 - 35,756,659 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001404051   ⟹   NP_001390980
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391735,752,074 - 35,756,659 (+)NCBI
RefSeq Acc Id: NM_001404052   ⟹   NP_001390981
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391735,752,074 - 35,756,659 (+)NCBI
RefSeq Acc Id: NP_001188389   ⟸   NM_001201460
- Peptide Label: isoform 1 precursor
- UniProtKB: P14430 (UniProtKB/Swiss-Prot),   Q52PG7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001390980   ⟸   NM_001404051
- Peptide Label: isoform 2 precursor
RefSeq Acc Id: NP_001390981   ⟸   NM_001404052
- Peptide Label: isoform 3 precursor
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P14431-F1-model_v2 AlphaFold P14431 1-200 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95938 AgrOrtholog
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC_class-I_related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I_a_a1/a2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:110558 UniProtKB/TrEMBL
MGD MGI:95938 ENTREZGENE
NCBI Gene H2-Q9 ENTREZGENE
PANTHER CLASS IB MHC ANTIGEN QA-2-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC CLASS I-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1-set UniProtKB/TrEMBL
  MHC_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen H2-Q9 PhenoGen
PRINTS MHCCLASSI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
SMART IGc1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF54452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt HA19_MOUSE UniProtKB/Swiss-Prot
  P14430 ENTREZGENE
  P14431 ENTREZGENE
  Q52PG7 ENTREZGENE, UniProtKB/TrEMBL