Ear3 (eosinophil-associated, ribonuclease A family, member 3) - Rat Genome Database

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Gene: Ear3 (eosinophil-associated, ribonuclease A family, member 3) Mus musculus
Analyze
No known orthologs.
Symbol: Ear3
Name: eosinophil-associated, ribonuclease A family, member 3
RGD ID: 1611454
MGI Page MGI
Description: Predicted to enable RNA nuclease activity and lipopolysaccharide binding activity. Predicted to be involved in chemotaxis; defense response to Gram-positive bacterium; and innate immune response in mucosa. Predicted to be active in extracellular space. Orthologous to human RNASE2 (ribonuclease A family member 2) and RNASE3 (ribonuclease A family member 3).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: eosinophil cationic-type ribonuclease 3; eosinophil-associated ribonuclease 3; mR; MR-3; mR3; murine ribonuclease 3; ribonuclease, RNase A family 3; Rn; Rnase3
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic Map14 NCBI


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9336452   PMID:15058383   PMID:21873635  


Genomics


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_017388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF017258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Protein Sequences
Protein RefSeqs NP_059084 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC53489 (Get FASTA)   NCBI Sequence Viewer  
  O35290 (Get FASTA)   NCBI Sequence Viewer  

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35290-F1-model_v2 AlphaFold O35290 1-156 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1858237 AgrOrtholog
Gene3D-CATH 3.10.130.10 UniProtKB/Swiss-Prot
InterPro RNaseA UniProtKB/Swiss-Prot
  RNaseA-like_dom_sf UniProtKB/Swiss-Prot
  RNaseA_AS UniProtKB/Swiss-Prot
  RNaseA_domain UniProtKB/Swiss-Prot
KEGG Report mmu:53876 UniProtKB/Swiss-Prot
MGD MGI:1858237 ENTREZGENE
NCBI Gene 53876 ENTREZGENE
PANTHER EOSINOPHIL CATIONIC PROTEIN UniProtKB/Swiss-Prot
  PTHR11437 UniProtKB/Swiss-Prot
Pfam RnaseA UniProtKB/Swiss-Prot
PhenoGen Ear3 PhenoGen
PRINTS RIBONUCLEASE UniProtKB/Swiss-Prot
PROSITE RNASE_PANCREATIC UniProtKB/Swiss-Prot
SMART RNAse_Pc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54076 UniProtKB/Swiss-Prot
UniProt ECP3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE